Paediatric Pharmacokinetics: Stages of Child Development
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Questions and Answers

What is the primary purpose of considering gestational age in paediatric pharmacokinetics?

  • To determine the fetal growth rate
  • To describe the progression of pregnancy (correct)
  • To identify the risk of fetal growth restriction
  • To establish the optimal dosage of medication

What is the main implication of fetal growth restriction on pharmacokinetics?

  • Altered drug distribution (correct)
  • Enhanced drug metabolism
  • Increased drug absorption
  • Unclear, as it is still a topic of research

What is the primary difference between licensed and unlicensed medications in paediatric practice?

  • Licensed medications are more expensive, while unlicensed medications are cheaper
  • Licensed medications have a higher efficacy, while unlicensed medications have a lower efficacy
  • Licensed medications are approved for paediatric use, while unlicensed medications are not (correct)
  • Licensed medications have a shorter half-life, while unlicensed medications have a longer half-life

Which age group is most likely to experience significant changes in pharmacokinetic and pharmacodynamic processes?

<p>Neonates (A)</p> Signup and view all the answers

What is the primary advantage of the oral route of absorption in paediatric patients?

<p>Ease of administration (A)</p> Signup and view all the answers

What is the primary challenge in prescribing medications in paediatric medicine?

<p>Limited pharmacokinetic data (B)</p> Signup and view all the answers

What is the primary purpose of plotting a growth chart in paediatric pharmacokinetics?

<p>To link stages of child development with ADME processes (A)</p> Signup and view all the answers

What is the primary implication of fetal growth restriction on drug absorption?

<p>Altered expression of drug transport proteins (A)</p> Signup and view all the answers

Which of the following ADME processes is most affected by the difference between licensed and unlicensed medications?

<p>Metabolism (C)</p> Signup and view all the answers

What is the primary challenge in considering medication errors in paediatric medicine?

<p>Dosing calculations (C)</p> Signup and view all the answers

What is the primary reason why pharmacokinetic and pharmacodynamic changes occur at different stages of child development?

<p>Changes in body composition (C)</p> Signup and view all the answers

What is the primary advantage of considering the stages of child development in pharmacokinetics?

<p>It enables healthcare professionals to anticipate pharmacokinetic and pharmacodynamic changes (B)</p> Signup and view all the answers

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