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Paediatric Pharmacokinetics: Stages of Child Development

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Paediatric Pharmacokinetics: Stages of Child Development

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Questions and Answers

What is the primary purpose of considering gestational age in paediatric pharmacokinetics?

To determine the fetal growth rate

To describe the progression of pregnancy (correct)

To identify the risk of fetal growth restriction

To establish the optimal dosage of medication

What is the main implication of fetal growth restriction on pharmacokinetics?

Altered drug distribution (correct)

Enhanced drug metabolism

Increased drug absorption

Unclear, as it is still a topic of research

What is the primary difference between licensed and unlicensed medications in paediatric practice?

Licensed medications are more expensive, while unlicensed medications are cheaper

Licensed medications have a higher efficacy, while unlicensed medications have a lower efficacy

Licensed medications are approved for paediatric use, while unlicensed medications are not (correct)

Licensed medications have a shorter half-life, while unlicensed medications have a longer half-life

Which age group is most likely to experience significant changes in pharmacokinetic and pharmacodynamic processes?

Neonates Signup and view all the answers

What is the primary advantage of the oral route of absorption in paediatric patients?

Ease of administration Signup and view all the answers

What is the primary challenge in prescribing medications in paediatric medicine?

Limited pharmacokinetic data Signup and view all the answers

What is the primary purpose of plotting a growth chart in paediatric pharmacokinetics?

To link stages of child development with ADME processes Signup and view all the answers

What is the primary implication of fetal growth restriction on drug absorption?

Altered expression of drug transport proteins Signup and view all the answers

Which of the following ADME processes is most affected by the difference between licensed and unlicensed medications?

Metabolism Signup and view all the answers

What is the primary challenge in considering medication errors in paediatric medicine?

Dosing calculations Signup and view all the answers

What is the primary reason why pharmacokinetic and pharmacodynamic changes occur at different stages of child development?

Changes in body composition Signup and view all the answers

What is the primary advantage of considering the stages of child development in pharmacokinetics?

It enables healthcare professionals to anticipate pharmacokinetic and pharmacodynamic changes Signup and view all the answers