Podcast
Questions and Answers
Which drug promotes relaxation during bladder filling without engaging muscarinic receptors?
Which drug promotes relaxation during bladder filling without engaging muscarinic receptors?
- Mirabegron (correct)
- Solifenacin
- Tolterodine
- Fesoterodine
Which drug inhibits calcium-dependent release of acetylcholine, adenosine triphosphate, and substance P in the detrusor muscle?
Which drug inhibits calcium-dependent release of acetylcholine, adenosine triphosphate, and substance P in the detrusor muscle?
- Vibegron (correct)
- Trospium
- Fesoterodine
- Mirabegron
Which drug can increase blood pressure and should be avoided in patients with renal disease or hypertension?
Which drug can increase blood pressure and should be avoided in patients with renal disease or hypertension?
- Mirabegron (correct)
- Solifenacin
- Vibegron
- Fesoterodine
Which drug is a substrate of CYP2D6 and CYP3A4 and is a moderate inhibitor of CYP2D6?
Which drug is a substrate of CYP2D6 and CYP3A4 and is a moderate inhibitor of CYP2D6?
Which drug has the main side effects of dry mouth and constipation and is a CYP2D6 and CYP3A4 Substrate?
Which drug has the main side effects of dry mouth and constipation and is a CYP2D6 and CYP3A4 Substrate?
Which drug achieves detrusor relaxation by activating beta-3-adrenoreceptors, resulting in activation of adenylyl cyclase and formation of cyclic adenosine monophosphate?
Which drug achieves detrusor relaxation by activating beta-3-adrenoreceptors, resulting in activation of adenylyl cyclase and formation of cyclic adenosine monophosphate?
Which drug requires dosage reduction for renal impairment?
Which drug requires dosage reduction for renal impairment?
Which drug inhibits calcium-dependent release of acetylcholine, adenosine triphosphate, and substance P in the detrusor muscle?
Which drug inhibits calcium-dependent release of acetylcholine, adenosine triphosphate, and substance P in the detrusor muscle?
Which drug may increase to 50 mg once daily after 4-8 weeks?
Which drug may increase to 50 mg once daily after 4-8 weeks?
Which drugs have been evaluated as non-traditional therapies for OAB?
Which drugs have been evaluated as non-traditional therapies for OAB?
Which drug is the third-line option for OAB?
Which drug is the third-line option for OAB?
What is the main reason for the high incidence of dry mouth as a side effect of oxybutynin?
What is the main reason for the high incidence of dry mouth as a side effect of oxybutynin?
Which drug has the greatest degree of M3 selectivity and is well-tolerated for overactive bladder?
Which drug has the greatest degree of M3 selectivity and is well-tolerated for overactive bladder?
What is the primary mechanism of action of oxybutynin?
What is the primary mechanism of action of oxybutynin?
Which medication can intensify the anticholinergic side effects when used in combination with oxybutynin?
Which medication can intensify the anticholinergic side effects when used in combination with oxybutynin?
What is the main side effect of darifenacin?
What is the main side effect of darifenacin?
Which formulation of oxybutynin is considered long-acting?
Which formulation of oxybutynin is considered long-acting?
What effect does darifenacin have on the M1 receptors in the brain and M2 receptors in the heart?
What effect does darifenacin have on the M1 receptors in the brain and M2 receptors in the heart?
Which factor can alter oxybutynin blood levels?
Which factor can alter oxybutynin blood levels?
What population is more likely to experience hallucinations and agitation as side effects of oxybutynin?
What population is more likely to experience hallucinations and agitation as side effects of oxybutynin?
Which medication has been reported to have both mydriasis and blurred vision as side effects?
Which medication has been reported to have both mydriasis and blurred vision as side effects?
What is a common side effect associated with the use of oxybutynin besides dry mouth?
What is a common side effect associated with the use of oxybutynin besides dry mouth?
What is the primary reason for the high incidence of dry mouth as a side effect of oxybutynin?
What is the primary reason for the high incidence of dry mouth as a side effect of oxybutynin?
Which formulation of oxybutynin is considered long-acting?
Which formulation of oxybutynin is considered long-acting?
Which drug has the greatest degree of M3 selectivity with minimal side effects on M1 and M2 receptors?
Which drug has the greatest degree of M3 selectivity with minimal side effects on M1 and M2 receptors?
What side effect is prominent in the pediatric and geriatric populations when using oxybutynin?
What side effect is prominent in the pediatric and geriatric populations when using oxybutynin?
Which medication can alter oxybutynin blood levels?
Which medication can alter oxybutynin blood levels?
Which drug can intensify the anticholinergic side effects when used in combination with oxybutynin?
Which drug can intensify the anticholinergic side effects when used in combination with oxybutynin?
Which drug promotes relaxation during bladder filling without engaging muscarinic receptors?
Which drug promotes relaxation during bladder filling without engaging muscarinic receptors?
Which drug achieves detrusor relaxation by activating beta-3-adrenoreceptors, resulting in activation of adenylyl cyclase and formation of cyclic adenosine monophosphate?
Which drug achieves detrusor relaxation by activating beta-3-adrenoreceptors, resulting in activation of adenylyl cyclase and formation of cyclic adenosine monophosphate?
What is the main side effect of darifenacin?
What is the main side effect of darifenacin?
What drug should be avoided in patients with renal disease or hypertension due to its potential to increase blood pressure?
What drug should be avoided in patients with renal disease or hypertension due to its potential to increase blood pressure?
What is the primary mechanism of action of mirabegron?
What is the primary mechanism of action of mirabegron?
Which drug can cause prolongation of the QT interval and should be avoided in patients with renal disease or hypertension?
Which drug can cause prolongation of the QT interval and should be avoided in patients with renal disease or hypertension?
What is the main side effect of trospium?
What is the main side effect of trospium?
Which drug achieves detrusor relaxation by inhibiting calcium-dependent release of neurotransmitters in the detrusor muscle?
Which drug achieves detrusor relaxation by inhibiting calcium-dependent release of neurotransmitters in the detrusor muscle?
What is the primary reason for avoiding mirabegron in patients with renal disease or hypertension?
What is the primary reason for avoiding mirabegron in patients with renal disease or hypertension?
What is the main side effect of fesoterodine?
What is the main side effect of fesoterodine?
Which drug is a substrate of CYP2D6 and CYP3A4 and is a moderate inhibitor of CYP2D6?
Which drug is a substrate of CYP2D6 and CYP3A4 and is a moderate inhibitor of CYP2D6?
What is the primary mechanism of action of oxybutynin?
What is the primary mechanism of action of oxybutynin?
What is the main side effect of tolterodine?
What is the main side effect of tolterodine?
What effect does solifenacin have on the QT interval at high doses?
What effect does solifenacin have on the QT interval at high doses?
Which medication achieves detrusor relaxation by causing flaccid paralysis in the detrusor and reducing bladder pressure?
Which medication achieves detrusor relaxation by causing flaccid paralysis in the detrusor and reducing bladder pressure?
