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Ocular Cholinergic Agonists and Antagonists

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Ocular Cholinergic Agonists and Antagonists

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Questions and Answers

What is the lethal dosage of Atropine in adults?

100mg (correct)

500mg

50mg

200mg

What is the antidote for Atropine overdose?

Scopolamine

Cyclopentolate

Physostigmine (correct)

Homatropine

What is the potency of Homatropine compared to Atropine?

10 times more potent than Atropine

Equal potency to Atropine

1/10 as potent as Atropine (correct)

Half as potent as Atropine

What is the primary use of Scopolamine?

As an alternative to Atropine in allergic patients Signup and view all the answers

What is the duration of Cyclopentolate's mydriatic and cycloplegic effect?

Less than 24 hours Signup and view all the answers

What is a common central nervous system effect of Cyclopentolate?

Drowsiness Signup and view all the answers

What is the commercial concentration of Tropicamide?

0.5% and 1.0% Signup and view all the answers

What is the clinical use of Tropicamide?

Dilated fundus examination Signup and view all the answers

What is a common ocular side effect of Atropine?

All of the above Signup and view all the answers

What is the primary difference between Atropine and Homatropine?

Potency Signup and view all the answers

Where does the efferent oculo-parasympathetic pathway originate?

E-W nucleus Signup and view all the answers

What is the neurotransmitter for both pre and post-ganglionic synapses?

Acetylcholine Signup and view all the answers

What is the name of the membrane-bound device used to deliver Pilocarpine?

Ocusertpilo-40 Signup and view all the answers

What is the mechanism of indirect Parasympathomimetics?

Blocking the breakdown of acetylcholine Signup and view all the answers

What is the name of the autoimmune disorder that affects voltage-gated calcium channels?

Lambert-Eaton Myasthenic Syndrome Signup and view all the answers

What is the name of the ocular cholinergic antagonist mentioned in the text?

Atropine Signup and view all the answers