27 Questions
Which neurotransmitter is involved in the efferent oculosympathetic pathway at the 1st order neuron trajectory?
Acetylcholine
What is the primary clinical use of 10% phenylephrine?
Posterior synechiae
Which direct sympathomimetic is structurally similar to epinephrine?
Phenylephrine
What is the effect of epinephrine on conjunctival vasoconstriction?
Conjunctival vasoconstriction
Which side effect is associated with topical epinephrine use?
Allergic dermatitis
What is the mechanism of action of 2.5% and 10% phenylephrine in clinical use?
Pupillary dilation
What is the primary neurotransmitter involved in the efferent oculosympathetic pathway at the 3rd order neuron trajectory?
Norepinephrine
Which side effect is associated with chronic use of phenylephrine?
Hypoxia of conjunctiva and iris
What are the systemic side effects associated with phenylephrine use?
Hypertension, tachycardia, subarachnoid hemorrhage
What clinical condition contraindicates the use of epinephrine in patients?
Narrow angles
What is the neurotransmitter in the sympathetic post-ganglionic synapse?
Norepinephrine
Which receptor type is involved in Ocular Autonomic Nervous System post-ganglionic structure?
Alpha (α) 1 receptors
What is the function of Iris Sphincter in the pupil?
Constriction via parasympathetic innervation
Which synapse in the sympathetic system has three components?
Post-ganglionic-organ effector synapse
In the Ocular Autonomic Nervous System, what neurotransmitter is present in some post-ganglionic sites?
Acetylcholine
Which nervous system regulates voluntary actions?
Somatic nervous system
What is the primary neurotransmitter in the central and pre-ganglionic synapse of the sympathetic system?
Acetylcholine
Which part of the eye dilates the pupil via sympathetic innervation?
Iris Dilator
Which drug interaction enhances the cardiovascular effect of tricyclic antidepressants and MAO inhibitors?
Guanethedine
What is the mode of action of 1% concentration paredrine?
Liberates norepinephrine from the pre-synaptic vesicle at the neuromuscular junction
What differentiates between central /2nd and 3rd neuron in Horner’s Syndrome?
Force duction test
What does a postcocaine anisocoria value of 0.8 mm indicate?
Horner's syndrome
What is the primary mode of action of Aproclonidine (Iopidine 0.5%)?
Decreases aqueous humor production
What is the mode of action of Brimonidine tartrate (Alphagan P 0.2%)?
Decreases aqueous production
What is the effect of Dapiprazole (Mydriolytic agent) on mydriasis?
Reversibly blocks ά-receptors on dilator muscle
Which ophthalmic beta blocker has a new mode of therapy with a maximum effect in 3 weeks?
Timolol Maleate (Timoptic)
'Rev-eyes 0.5%' is associated with which side effect?
Superficial punctate keratitis
Test your knowledge of ocular adrenergic agonist and antagonist drugs, as well as the nervous system related to the eye. This quiz covers topics such as efferent innervation, sympathetic and parasympathetic systems, and the autonomic nervous system.
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