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Questions and Answers
What type of glycosidic bonds connect glucose molecules in amylopectin?
What type of glycosidic bonds connect glucose molecules in amylopectin?
Which polysaccharide is not hydrolyzed by human enzymes due to its glycosidic bond type?
Which polysaccharide is not hydrolyzed by human enzymes due to its glycosidic bond type?
What are the primary enzymes in human saliva that digest starches?
What are the primary enzymes in human saliva that digest starches?
Which animal can break down cellulose due to the presence of specific enzymes provided by bacteria in their digestive system?
Which animal can break down cellulose due to the presence of specific enzymes provided by bacteria in their digestive system?
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What is the main difference between amylose and amylopectin structure?
What is the main difference between amylose and amylopectin structure?
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What is the most stable form of pentoses and hexoses?
What is the most stable form of pentoses and hexoses?
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What does the position of the –OH group on C1 determine in fructose?
What does the position of the –OH group on C1 determine in fructose?
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Which carbon determines the sweetness of fructose compared to sucrose?
Which carbon determines the sweetness of fructose compared to sucrose?
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In the formation of the Haworth structure, which group reacts with the carbonyl carbon?
In the formation of the Haworth structure, which group reacts with the carbonyl carbon?
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What distinguishes the α and β isomers of D-glucose?
What distinguishes the α and β isomers of D-glucose?
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What is the five-carbon sugar found in RNA?
What is the five-carbon sugar found in RNA?
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What type of bond is formed between the sugar and phosphate in adjacent nucleotides?
What type of bond is formed between the sugar and phosphate in adjacent nucleotides?
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What does the ‘folding’ of the carbon chain into a hexagon represent in sugar chemistry?
What does the ‘folding’ of the carbon chain into a hexagon represent in sugar chemistry?
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Which two carbons are primarily involved in the difference between the structural isomers of fructose?
Which two carbons are primarily involved in the difference between the structural isomers of fructose?
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What characterizes the primary structure of a nucleic acid?
What characterizes the primary structure of a nucleic acid?
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What suffix is added to nucleosides of DNA for differentiation?
What suffix is added to nucleosides of DNA for differentiation?
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What structural element forms the corners of the ring in the Haworth structure?
What structural element forms the corners of the ring in the Haworth structure?
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What is the main difference between the sugars found in DNA and RNA?
What is the main difference between the sugars found in DNA and RNA?
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Which statement about the sugar-phosphate backbone of nucleic acids is true?
Which statement about the sugar-phosphate backbone of nucleic acids is true?
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How are the names of nucleosides containing purines generally formed?
How are the names of nucleosides containing purines generally formed?
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What type of molecules are nucleic acids primarily composed of?
What type of molecules are nucleic acids primarily composed of?
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Which of the following monosaccharides is classified as an aldohexose?
Which of the following monosaccharides is classified as an aldohexose?
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How is the D or L isomer determined in Fischer projections of monosaccharides?
How is the D or L isomer determined in Fischer projections of monosaccharides?
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Which compound's accumulation can lead to galactosemia?
Which compound's accumulation can lead to galactosemia?
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Which of the following serves as a building block for sucrose and lactose?
Which of the following serves as a building block for sucrose and lactose?
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What characterizes D-glucose in terms of its structure?
What characterizes D-glucose in terms of its structure?
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Which of the following statements is true about the difference between D-glucose and D-galactose?
Which of the following statements is true about the difference between D-glucose and D-galactose?
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Which of the following compounds is identified as a ketopentose?
Which of the following compounds is identified as a ketopentose?
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What is the direction of the two strands in the sugar-phosphate backbone?
What is the direction of the two strands in the sugar-phosphate backbone?
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What process must HIV initiate to replicate its genetic material inside the host cell?
What process must HIV initiate to replicate its genetic material inside the host cell?
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What type of structure do monosaccharides typically form in solution?
What type of structure do monosaccharides typically form in solution?
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What function does reverse transcriptase serve in retroviruses like HIV?
What function does reverse transcriptase serve in retroviruses like HIV?
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Which drug acts as a nucleoside analog similar to thymidine?
Which drug acts as a nucleoside analog similar to thymidine?
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What is the newly formed viral DNA referred to after it integrates with the host cell DNA?
What is the newly formed viral DNA referred to after it integrates with the host cell DNA?
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How does treatment for AIDS typically target HIV-1?
How does treatment for AIDS typically target HIV-1?
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What role do nucleoside analogs play in the treatment of HIV?
What role do nucleoside analogs play in the treatment of HIV?
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Which of the following is NOT one of the drugs mentioned that act as nucleoside analogs?
Which of the following is NOT one of the drugs mentioned that act as nucleoside analogs?
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Which polysaccharide consists of glucose units joined by α-1,6-glycosidic bonds?
Which polysaccharide consists of glucose units joined by α-1,6-glycosidic bonds?
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What is the main difference between amylose and cellulose?
What is the main difference between amylose and cellulose?
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Which statement accurately describes the composition of starch?
Which statement accurately describes the composition of starch?
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What is the primary function of glycogen in animals?
What is the primary function of glycogen in animals?
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How are the glucose units in cellulose linked together?
How are the glucose units in cellulose linked together?
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What percentage of starch is made up of amylose?
What percentage of starch is made up of amylose?
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Which enzyme is responsible for digesting starch in the human body?
Which enzyme is responsible for digesting starch in the human body?
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What term is used for the storage form of glucose in plants?
What term is used for the storage form of glucose in plants?
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Study Notes
Nucleic Acids
- Nucleic acids are large molecules found in cell nuclei, storing information for cellular growth and reproduction.
- Two main types exist: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
- Both are polymers of repeating monomer units called nucleotides.
- Each nucleotide has three components: a nitrogenous base, a five-carbon sugar, and a phosphate group.
- The nitrogenous bases are derivatives of pyrimidine or purine.
- In RNA, the five-carbon sugar is ribose; in DNA, it's deoxyribose (similar to ribose but without an oxygen atom).
- Nucleosides are formed by combining a sugar and a base via an N-glycosidic bond.
- Nucleotides are nucleosides with a phosphate group attached to the sugar's 5' carbon.
- Only 5'-monophosphate nucleotides are found in DNA and RNA.
Nucleosides and Nucleotides
- Nucleosides are combinations of a sugar and a base.
- Nucleotides include a nucleoside plus a phosphate group.
Primary Structure of Nucleic Acids
- Nucleic acids are polymers of nucleotides.
- Nucleotides are linked by phosphodiester bonds between the 3' hydroxyl group of one sugar and the 5' phosphate group of the next.
- The sequence of bases forms the primary structure.
- The sequence is read from the 5' end to the 3' end (5'→3').
Viruses
- Viruses are small particles (3-200 genes) requiring a host cell to replicate.
- They contain either DNA or RNA, but not both.
- They infect a host cell and use its resources to replicate.
Reverse Transcription
- Retroviruses contain RNA as genetic material.
- They use an enzyme called reverse transcriptase to make DNA from the RNA template.
- The resulting DNA integrates into the host cell's DNA.
- Reverse transcriptase inhibitors are used to treat HIV infections.
Acquired Immune Deficiency Syndrome (AIDS)
- AIDS is caused by HIV infection.
- HIV infects T4 lymphocytes (crucial to the immune system).
- Treatment targets reverse transcription and protein synthesis.
- Nucleoside analogs mimic normal nucleosides, hindering reverse transcriptase.
Carbohydrates
- Carbohydrates are made of carbon, hydrogen, and oxygen.
- Simple sugars have the formula Cn(H₂O)n, once thought to be hydrated carbons.
- In photosynthesis, energy from the sun is used to produce carbohydrates.
- Respiration in cells releases chemical energy from carbohydrates.
- Monosaccharides are simple sugars, cannot be split further by hydrolysis.
- Disaccharides form when two monosaccharides combine using a glycosidic bond.
- Polysaccharides are composed of multiple monosaccharides.
Types of Carbohydrates
- Monosaccharides are the simplest form of sugar.
- Disaccharides combine two monosaccharides.
- Polysaccharides consist of multiple monosaccharides linked to form long chains.
Monosaccharides
- Monosaccharides are sugars with 3-8 carbon atoms.
- The carbonyl group (aldehyde or ketone) dictates whether it's an aldose or ketose.
- Monosaccharides are given a 'D' or 'L' designation based on the spatial arrangement around the chiral carbon furthest from the carbonyl group.
- Monosaccharides form cyclic structures (Haworth projection).
- Monosaccharides in different ring structures are called anomers (alpha or beta isomers).
Disaccharides
- Two monosaccharides joined together by a glycosidic bond.
- Different glycosidic bonds lead to different disaccharides (maltose, sucrose, lactose).
- Lactose (milk sugar)
- Sucrose (table sugar)
- Maltose (malt sugar)
Polysaccharides
- Long chains of monosaccharides linked by glycosidic bonds.
- Starch, glycogen, and cellulose are major polysaccharides in various roles.
- Starch (plants): storage form of glucose, has amylose and amylopectin.
- Glycogen (animals): storage form of glucose, highly branched.
- Cellulose (plants): structural component, humans cannot digest.
Other Important Carbohydrates
- Fructose (fruit sugar): a ketohexose, sweeter than glucose
- Galactose: aldohexose that differs from glucose only at one carbon.
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Description
Explore the fundamental concepts of nucleic acids, including DNA and RNA. Learn about their structures, components like nucleotides and nucleosides, and their roles in cellular processes. This quiz covers key molecular biology concepts pertinent to nucleic acids.