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Nuclear Medicine: Preparation of Radiopharmaceuticals

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What is the typical thickness range of scintillators used in gamma cameras for medical imaging?

6 to 12.5 mm

What happens to the energy of gamma photons after interacting with the scintillation crystal?

It is converted to visible optical photons

What is the function of the photomultiplier tube (PMT) in gamma detection?

To detect and convert optical photons into electrical signals

What is the relationship between the electric current and the number of detected optical photons in a PMT?

<p>Directly proportional</p> Signup and view all the answers

What is the peak wavelength of the optical photons transmitted by the NaI scintillator?

<p>415 nm</p> Signup and view all the answers

What happens to the photocathode when it receives optical photons in a PMT?

<p>It liberates photoelectrons</p> Signup and view all the answers

What is the typical method of preparing radiopharmaceuticals?

<p>Simple mixing or shaking at room temperature</p> Signup and view all the answers

What type of syringes are used to transfer radiopharmaceutical components?

<p>Shielded syringes</p> Signup and view all the answers

What is the purpose of a glove box in radiopharmaceutical preparation?

<p>To provide a sterile environment for preparation</p> Signup and view all the answers

What is a characteristic of the surfaces in a radiopharmaceutical preparation room?

<p>Continuous floors, gloss-painted walls, and formica-topped or stainless steel benches</p> Signup and view all the answers

How do workers typically enter a radiopharmaceutical preparation room?

<p>Via an air lock and changing room</p> Signup and view all the answers

What type of device is commonly used in preparing PET radiopharmaceuticals?

<p>Automated synthesis device</p> Signup and view all the answers

What is a crucial aspect to consider when selecting a scintillator for gamma ray detection in clinical use?

<p>High atomic number</p> Signup and view all the answers

What is a common issue with Sodium iodide (NaI) scintillators?

<p>They are fragile and absorb moisture</p> Signup and view all the answers

What is a benefit of using a scintillator with a high light output?

<p>It enhances imaging performance</p> Signup and view all the answers

What is the primary reason Sodium iodide (NaI) scintillators are widely used in conventional gamma ray imaging systems?

<p>They have been used traditionally</p> Signup and view all the answers

What is a characteristic of CsI(Na) scintillators?

<p>They have a high atomic number</p> Signup and view all the answers

Why are NaI scintillators required to be sealed in airtight containers?

<p>To protect them from moisture</p> Signup and view all the answers

What is the primary limitation of using collimators in gamma imaging?

<p>Gamma photons not passing through the collimator's holes are absorbed by the material</p> Signup and view all the answers

What is the purpose of the hexagonal structured holes in parallel hole collimators?

<p>To maximise the exposed area of the gamma camera detector</p> Signup and view all the answers

What is the main advantage of improving the ability of the gamma camera to detect primary gamma photons?

<p>It improves the gamma imaging outcome</p> Signup and view all the answers

What determines the appropriate type of collimator for gamma ray detection?

<p>FOV dimension, targeted areas' dimensions, and desired level of sensitivity and spatial resolution</p> Signup and view all the answers

What is the function of the scintillator in gamma imaging?

<p>To map gamma rays onto the image</p> Signup and view all the answers

What is the common material used in making the high density plate of parallel hole collimators?

<p>Lead</p> Signup and view all the answers

What is the main reason for minimizing scattered gamma photon penetration in the collimator body?

<p>To avoid inaccurate data projection on the gamma image</p> Signup and view all the answers

What is a key difference between parallel-hole collimators and non-parallel hole collimators?

<p>Their field of view</p> Signup and view all the answers

Which type of collimator is suitable for scanning small targeted areas?

<p>Converging collimator</p> Signup and view all the answers

What is the primary application of pinhole collimators?

<p>Small organ imaging procedures</p> Signup and view all the answers

What is the typical diameter range of the aperture in a pinhole collimator?

<p>2 to 6 mm</p> Signup and view all the answers

What is a key advantage of pinhole collimators in nuclear medicine clinics?

<p>Effective examination of small organs</p> Signup and view all the answers

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