Nuclear Medicine Physics: Preparation of Radiopharmaceuticals
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Questions and Answers

What is the role of radionuclide in medical imaging?

  • To absorb gamma rays
  • To focus gamma rays
  • To produce medical gamma images
  • To signal the location of the radiopharmaceutical by the emission of gamma rays (correct)
  • What type of gamma rays does 99mTc emit?

  • 150keV gamma rays
  • 100keV gamma rays
  • 141keV gamma rays (correct)
  • 200keV gamma rays
  • What is used in place of a lens in gamma cameras?

  • A mirror
  • A filter
  • A multi-hole collimator (correct)
  • A prism
  • What is the purpose of a scintillation crystal?

    <p>To convert gamma rays into optical light</p> Signup and view all the answers

    What are the components of a gamma camera?

    <p>Light guide, photomultiplier tube array, radiation shielding, scintillation crystal, collimator, and electronics for energy positioning</p> Signup and view all the answers

    What is the purpose of a gamma camera?

    <p>To produce medical gamma images</p> Signup and view all the answers

    What is the typical environment for preparing radiopharmaceuticals?

    <p>A sterile workstation, such as a glove box or laminar down-flow cabinet</p> Signup and view all the answers

    What is the range of thicknesses for scintillators in gamma cameras for medical imaging?

    <p>6 to 12.5 mm</p> Signup and view all the answers

    What is the purpose of shielded syringes in radiopharmaceutical preparation?

    <p>To transfer the components between sterile vials</p> Signup and view all the answers

    What type of cabinet is used in radiopharmaceutical preparation?

    <p>A sterile laminar down-flow cabinet</p> Signup and view all the answers

    What happens when gamma photons interact with the scintillation crystal?

    <p>The energy of the photons is deposited in the crystal and converted to visible optical photons</p> Signup and view all the answers

    What is a characteristic of the surfaces in a radiopharmaceutical preparation workstation?

    <p>They are impervious</p> Signup and view all the answers

    What is the purpose of the photomultiplier tube (PMT) in gamma detection?

    <p>To detect and convert optical photons into a measurable electrical signal</p> Signup and view all the answers

    Why are automated synthesis devices used in PET radiopharmaceutical preparation?

    <p>To reduce the preparation time</p> Signup and view all the answers

    What is the relationship between the electric current and the number of detected optical photons in a PMT?

    <p>Directly proportional</p> Signup and view all the answers

    What is a necessary step before entering a radiopharmaceutical preparation workstation?

    <p>Entering through an air lock and changing room</p> Signup and view all the answers

    What is the peak wavelength of the optical photons transmitted by the NaI scintillator?

    <p>415 nm</p> Signup and view all the answers

    What is the result of the interaction between the optical photons and the photocathode in a PMT?

    <p>Liberation of photoelectrons</p> Signup and view all the answers

    What is the typical range of thickness for parallel hole collimators manufactured for traditional gamma cameras?

    <p>25-80 mm</p> Signup and view all the answers

    What is the purpose of the lead septa in parallel hole collimators?

    <p>To surround identical holes</p> Signup and view all the answers

    What is the advantage of parallel hole collimators compared to pinhole collimators?

    <p>They provide a superior level of sensitivity</p> Signup and view all the answers

    What happens to the spatial resolution quality of the gamma camera as the diameter of the collimator's holes increases?

    <p>It degrades</p> Signup and view all the answers

    Why is the energy of the gamma photons important in selecting the appropriate parallel-hole collimator?

    <p>It determines the septal thickness</p> Signup and view all the answers

    What is the angle at which incident gamma photons pass through the parallel hole collimator?

    <p>At a perpendicular angle</p> Signup and view all the answers

    What is the main limitation of conventional planar gamma imaging?

    <p>It lacks depth information</p> Signup and view all the answers

    What is the purpose of emission tomography?

    <p>To address deficiencies of conventional planar gamma imaging</p> Signup and view all the answers

    How many views are typically taken in Single-photon emission computed tomography (SPECT)?

    <p>60</p> Signup and view all the answers

    What is the approximate scanning time required for Single-photon emission computed tomography (SPECT)?

    <p>30 mins</p> Signup and view all the answers

    What is the number of counts acquired in a typical SPECT scan?

    <p>3 million</p> Signup and view all the answers

    What type of collimators are used for radionuclides up to 400 keV?

    <p>Medium-energy collimators</p> Signup and view all the answers

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