8 Questions
Which enzyme is primarily responsible for the synthesis of prostaglandins involved in pain, fever, and inflammation?
COX-2
Which of the following prostaglandins is involved in maintaining the patency of the ductus arteriosus in the fetus?
Prostaglandin E2 (PGE2)
Which enzyme is responsible for the synthesis of thromboxane, a potent vasoconstrictor and promoter of platelet aggregation?
COX-1
Which of the following prostaglandins is produced by endothelial cells and acts as a vasodilator and inhibitor of platelet aggregation?
Prostaglandin I2 (PGI2)
Which enzyme pathway is primarily responsible for the synthesis of leukotrienes, mediators of bronchoconstriction and inflammation in asthma?
Lipo-Oxygenase (LOX)
Which prostaglandin is involved in the regulation of renal blood flow?
Prostaglandin E2 (PGE2)
Which prostaglandin is primarily involved in the contraction of the uterus during menstruation in non-pregnant women, causing dysmenorrhea (menstrual cramps)?
Prostaglandin F2α (PGF2α)
Which prostaglandin is involved in the maintenance of the protective mucosal lining in the gastrointestinal tract, preventing peptic ulcers?
Prostaglandin E2 (PGE2)
Test your knowledge on Non-steroidal Anti-inflammatory drugs (NSAIDs) and their mechanism of action inhibiting Cyclo-Oxygenase (COX) Enzymes. Learn about the different types of COX enzymes, their functions, and the synthesis of Prostaglandins. Discover the role of COX-1, COX-2, and the newly investigated COX-3.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
