NMDA Receptors and Synaptic Plasticity Quiz

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19 Questions

Which type of receptor is GABAA?

Ionotropic Cl- Channel

Which drugs bind to the benzodiazepine site on GABAA receptors?

Diazepam, Lorazepam, Alprazolam

What is the most common inhibitory neurotransmitter in the central nervous system (CNS)?

GABA

Which receptors do barbiturates interact with?

GABAA and glutamate receptors

What is the main advantage of nonbenzo drugs compared to benzos?

They have a shorter half-life

Which receptor does baclofen primarily act on?

GABAB receptor

Which gas is commonly used for conscious sedation?

Propofol

Which drug is given with a decarboxylase inhibitor to prevent conversion to dopamine in the periphery and keep plasma L-dopa levels high?

Carbidopa

Which receptors do antipsychotics block?

D2-Like receptors

Which drug is an example of an atypical antipsychotic?

Olanzapine

Which drug inhibits VMAT2, preventing dopamine from entering vesicles and lowering dopamine release?

Reserpine

Which receptor is NOT a metabotropic receptor?

5HT_3

What is the function of 5HT autoreceptors?

Inhibit serotonin release

Which class of antidepressants inhibits the reuptake of both serotonin and norepinephrine?

Tricyclic antidepressants (TCA)

What is the primary function of dopamine in the brain?

Movement

Which receptor is responsible for control of synaptic plasticity and memory?

NMDA receptor

Which ion(s) can pass through the unique NMDA receptor?

All of the above

What is the role of Glu and Gly in opening the NMDA receptor?

Glu and Gly open the NMDA receptor

What is the main excitatory action of Glutamate on motor neurons?

Activation of AMPA receptors

Test your knowledge about NMDA receptors and their role in synaptic plasticity and memory function. Learn about the unique characteristics of NMDA receptors, their activation, and ion channel blocking. Explore how glutamate and glycine play a role in opening NMDA receptors.

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