Newborn Physiology and Blood Quiz
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Questions and Answers

When does meconium most often pass in a newborn?

  • After 48 hours
  • Sometimes up to 72 hours
  • In the first 12 hours
  • In the first day (correct)
  • Up to 60 hours

How many times do the glands of the gastric mucosa form and increase in size as a child grows?

  • 5 times
  • 20 times
  • 15 times
  • 25 times (correct)
  • 10 times

What are "Bish's lumps" in young children?

  • Fatty liver dystrophy
  • Giant Gaucher fat cells
  • Fat deposits in the thickness of the cheeks (correct)
  • Protein reserve
  • Fat deposits on the abdomen

Which acid maintains a slightly acidic reaction in the stomach of a newborn?

<p>Hydrochloric (B)</p> Signup and view all the answers

What is the primary component found in the gallbladder of young children?

<p>A small amount of mucin (B)</p> Signup and view all the answers

At what age does the lipase level reach the adult level?

<p>17 years (E)</p> Signup and view all the answers

What does the lipase in breast milk mainly contribute to the absorption of?

<p>Fats (A)</p> Signup and view all the answers

At what age do newborns have a large secretion of saliva?

<p>3-4 months (E)</p> Signup and view all the answers

What is the predominant type of intestinal flora in a baby?

<p>Bifidobacteria (E)</p> Signup and view all the answers

What is the largest gland in a child's body?

<p>Liver (C)</p> Signup and view all the answers

A newborn, on the 3-4th day of life, typically exhibits a change in the chemical composition of their urine. Which of the following changes is most commonly observed?

<p>Increased uric acid salts (D)</p> Signup and view all the answers

What is the normal relative density of urine in a newborn?

<p>1002-1004 (E)</p> Signup and view all the answers

What is the normal range for leukocytes at birth in a newborn?

<p>10-20×10<sup>9</sup> (E)</p> Signup and view all the answers

Which of the following is NOT a morphological feature of the kidney in a newborn?

<p>Well-developed cortex (A)</p> Signup and view all the answers

Which of the following is NOT a functional feature of the kidneys?

<p>Poorly developed filtration capacity (D)</p> Signup and view all the answers

At what age does glomerular filtration reach the adult level?

<p>5 years (D)</p> Signup and view all the answers

How does the filtration capacity of the kidneys in children compare to that of adults?

<p>Lower than in adults (B)</p> Signup and view all the answers

Where is the renal pelvis located in young children?

<p>Located extrarenally (C)</p> Signup and view all the answers

What are the defining characteristics of the muscular system in a newborn?

<p>Predominance of hypertonicity of the flexor muscles (C)</p> Signup and view all the answers

Which of the following factors contribute to the tendency of infants to cool and overheat easily?

<p>Insufficient blood supply to the skin (A), Imperfect thermoregulation (C), Thin epidermis (E)</p> Signup and view all the answers

Why are bones in young children less fragile than in adults?

<p>Dense bone structure (E)</p> Signup and view all the answers

Which of the following bone tissues is formed by chondral osteogenesis?

<p>Flat bones (B)</p> Signup and view all the answers

How are ribs attached to the sternum in newborns?

<p>Vertically (C)</p> Signup and view all the answers

What are the reasons for a more frequent pulse in children?

<p>Intensive metabolism (C), Active motor activity (E)</p> Signup and view all the answers

When does the anatomical closure of the arterial duct occur in most children?

<p>In the first half of life (E)</p> Signup and view all the answers

What are the reasons for the shunt through the oval window to stop functioning?

<p>Increased resistance in the pulmonary bed (C)</p> Signup and view all the answers

At what ages does blood pressure increase most rapidly in children?

<p>In puberty (C)</p> Signup and view all the answers

How does blood pressure in the lower extremities compare to that in the upper extremities?

<p>20-30% lower (A)</p> Signup and view all the answers

What is the typical shape of a newborn's heart?

<p>Oval (D)</p> Signup and view all the answers

What is the normal heart rate for a newborn?

<p>130 (E)</p> Signup and view all the answers

What is the normal heart rate for a 5-year-old child per minute?

<p>100 (B)</p> Signup and view all the answers

How is blood pressure (mm Hg) calculated in children over 1 year old?

<p>100 + n (E)</p> Signup and view all the answers

Which of the following describes the functional nature of systolic murmur?

<p>Accompanied by a &quot;cat purr&quot; (A), Increases in a vertical position (C), Occupies the beginning of systole (E)</p> Signup and view all the answers

What is physiological tachycardia in a newborn associated with?

<p>Immaturity of myocardiocytes (B), Large volume of heart cavities (E)</p> Signup and view all the answers

What is low blood pressure in young children primarily due to?

<p>High resistance of peripheral vessels (A), Low stroke volume of the heart (E)</p> Signup and view all the answers

During intrauterine development, at what stage does the formation of the interventricular septum occur?

<p>4 weeks (B)</p> Signup and view all the answers

How does the size of a newborn's heart compare to that of an adult?

<p>Occupies a relatively smaller volume of the chest (B), Relatively smaller than in an adult (E)</p> Signup and view all the answers

When does the differentiation of the parts of the heart end?

<p>10-14 years (C)</p> Signup and view all the answers

What is percussion?

<p>Analysis of sounds during percussion (D)</p> Signup and view all the answers

What can be measured using spirometry?

<p>Residual volume (A), Functional residual capacity (B), Lung capacity (D), Tidal volume (E)</p> Signup and view all the answers

Flashcards

When is meconium typically passed in a newborn?

During the first 12 hours after birth, the passage of meconium, the first stool of a newborn, is a normal and expected event.

How many times do the gastric mucosa glands increase in size during childhood?

The glands within the stomach lining increase in size tenfold as a child grows. This signifies the development and maturation of the digestive system.

What are Bish's lumps?

These lumps, also known as "Bish's lumps", are deposits of fat in the cheeks of young children. They are a normal developmental feature and not a cause for concern.

What acid is involved in maintaining a slightly acidic environment in a newborn's stomach?

The slightly acidic environment in the stomach of a newborn is maintained by the presence of hydrochloric acid. It helps in the initial breakdown of food.

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What is a major component of a child's gallbladder?

In children, their gallbladder contains a large amount of glycocholic acid, a bile acid that helps in the breakdown of fats.

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At what age does lipase level reach adult levels?

The level of lipase, an enzyme that aids in fat digestion, reaches the level found in adults by around 12 years of age.

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What does the lipase in breast milk help absorb?

Lipase present in breast milk facilitates the absorption of fats. It is crucial for a newborn's healthy growth and development.

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When is saliva secretion in a newborn at its highest?

Newborns have a significant increase in saliva production around 3-4 months of age. This helps them with suckling and early digestion.

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Which bacteria dominates the intestinal flora of a baby?

Bifidobacteria are the predominant type of bacteria found in the gut of a baby. They play a crucial role in healthy digestion.

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What is the largest gland in a child's body?

The liver is the largest gland in a child's body. It plays a vital role in digestion, detoxification, and many other essential physiological functions.

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What is the typical change in urine composition on the 3-4th day of a newborn's life?

A newborn's urine typically shows an increase in uric acid salts on the 3-4th day after birth. This is normal and related to their metabolic process.

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What is the expected range of urine specific gravity for a newborn?

The normal urine specific gravity for a newborn is between 1002-1004. This indicates a healthy hydration balance.

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What is the normal range of leukocyte count at birth?

A normal leukocyte count at birth ranges from 10-20*109/l. This reflects the initial immune response of the newborn.

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What is a key morphological feature of the kidney in a newborn?

The kidneys of a newborn are characterized by weak vascularization. This means they lack the fully developed blood vessel network compared to adults.

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What is a key functional feature of the kidneys in a newborn?

Newborn kidneys are not fully equipped with efficient filtration capacity, leading to potential for fluid accumulation and waste buildup.

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When does the glomerular filtration rate achieve adult levels?

The glomerular filtration rate, a measure of kidney function, reaches the level of an adult around 5 years of age.

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How does filtration capacity in children compare to adults?

Children, compared to adults, have lower filtration capacity in their kidneys. This means their kidneys are less efficient at filtering waste products.

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What is a characteristic feature of the renal pelvis in young children?

The specialized muscle layer of the renal pelvis in young children is well-developed, but the muscle layer is not yet fully mature. This provides support and flexibility.

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What formula predicts the eruption of baby teeth?

The formula for calculating the eruption of baby teeth is n-4, where n is the age in months. So, a 4-month-old baby will have 0 teeth (4-4=0).

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What bones are examined to determine bone age?

Hand bones are a reliable indicator of bone age, which is different from chronological age. These can be used by doctors to assess a child's development.

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What causes physiological jaundice in newborns?

Physiological jaundice in newborns is caused by the breakdown and processing of excess red blood cells, a normal process after birth. The bilirubin level is too high to process quickly and causes jaundice.

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How does brown adipose tissue in infants differ from white adipose tissue?

Brown adipose tissue, found in infants, is different from white fat because its main function is thermogenesis, or heat production. It has a higher content of mitochondria, which helps with energy production.

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What is a characteristic feature of the skeletal system in children?

The child's skeleton is characterized by a thicker periosteum, a membrane lining the bones. This allows for faster bone growth during childhood.

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What is a typical feature of the muscle system in a newborn?

Muscle hypertonicity, or increased muscle tone, is typical in neonates, especially in the flexor muscles. This is due to the neurodevelopment of the baby.

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Why are infants more susceptible to cooling and overheating?

Infants are prone to temperature fluctuations due to their imperfect thermoregulation. This is caused by their immature thermoregulatory center and lack of regulation.

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Why are bones less fragile in young children?

Bones in children are less fragile due to their higher water content, which provides flexibility and resilience during growth stages.

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What type of bone tissue is formed through chondral osteogenesis?

Chondral osteogenesis is the process of bone formation from cartilage. It is responsible for the development of bones like the diaphyses of tubular bones, clavicles, and lower jaw.

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How are ribs attached to the sternum in newborns?

The ribs in newborns attach to the sternum at an obtuse angle, unlike adults where they are more perpendicular. This is a developmental characteristic.

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What is the main reason for a child's higher heart rate?

The rapid growth and development of a child's body system require a faster heart rate to meet the increased metabolic needs. This is why children have a faster heartbeat.

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When does the arterial duct close in most children?

The closure of the arterial duct, a temporary blood vessel connection in the fetus, typically happens at birth. This is the natural process of heart development.

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What contributes to the closure of the oval window in the heart?

Increased blood flow to the right atrium, where the blood from the body enters the heart, contributes to stopping the functionality of the oval window. This is a natural part of heart development after birth.

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In which age group does blood pressure increase most rapidly?

Blood pressure increases rapidly during puberty due to hormonal changes and the development of body systems. This is a natural process.

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How does blood pressure in the lower extremities compare to the upper extremities?

Blood pressure in the lower extremities is typically higher than in the upper extremities by 20-30%. This is due to the force of gravity and the distance from the heart.

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How is the heart shaped in a newborn?

The heart of a newborn is shaped like a sphere, unlike the more elongated shape found in adults. This is due to its developmental stage.

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What is the normal heart rate for a newborn?

A newborn's heart rate is typically around 130 beats per minute. This is a normal range for their rapid growth and development.

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What is the normal heart rate for a 5-year-old?

A child's heart rate decreases as they grow older. A five-year-old typically has a heart rate of about 100 beats per minute.

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How to calculate blood pressure in children over 1 year old?

Blood pressure in children over 1 year old can be estimated using the formula 90+2n, where n is the age in years. This gives a basic estimate.

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What is a functional systolic murmur?

A functional systolic murmur happens at the beginning of systole, the phase of the heart cycle when blood is pumped out. It is a normal finding in some children.

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What is physiological tachycardia in a newborn associated with?

Physiological tachycardia in a newborn is associated with sympathicotonia, a predominance of sympathetic nervous system activity. This helps regulate the heart beat.

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What is a common reason for low blood pressure in young children?

Low blood pressure in young children often results from a smaller volume of circulating blood. This is normal during early development.

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When does the interventricular septum form during intrauterine development?

The interventricular septum, the wall separating the left and right ventricles of the heart, forms during the fourth week of intrauterine development. This is a crucial step in heart development.

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How does the heart size of a newborn compare to an adult?

The heart of a newborn is relatively larger in proportion to body size compared to an adult. The size of the left and right ventricles are roughly equal, which is different from an adult.

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When does heart differentiation reach completion?

The differentiation of the different parts of the heart, like the chambers and valves, reaches completion between 10-14 years of age. This is a key period in heart development.

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What is percussion in a physical exam?

Percussion is a technique in physical examination where you tap on different parts of the body to listen to the sounds produced. This helps to assess things like lung health.

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What can spirometry measure?

Spirometry is a test that measures various lung volumes, including residual volume. It helps assess the function of the lungs.

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What does spirography examine?

Spirography, a test using a spirometer, is used to examine external respiration, which is the process of inhaling oxygen and exhaling carbon dioxide.

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What is the first step in a physical exam?

A physical examination starts with a thorough inspection of the skin. This helps assess for any abnormalities or clues to underlying conditions.

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What is one function of the skin in newborns?

One of the functions of the skin in newborns is respiratory. This means the skin can play a role in gas exchange, particularly in early life.

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What is a characteristic feature of skin cells in newborns?

Skin cells in newborns primarily contain connective tissue, which provides structural support and flexibility. This is part of the development of the skin.

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What causes physiological jaundice in newborns?

Physiological jaundice in newborns is caused by the breakdown and processing of excess red blood cells, a normal process after birth. The bilirubin level is too high to process quickly and causes jaundice.

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Why is the skin of a newborn transparent and pink?

The skin of a newborn is transparent and pink due to the absence of bilirubin, a pigment that is broken down and processed after birth. This gives the skin a light, translucent appearance.

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What is the primary reason for weak thermoregulation in newborns?

Poor thermoregulation in newborns is related to the immature thermoregulatory center in the brain. The center isn't fully developed yet and needs time to function effectively.

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Where is the thickness of the fat layer measured?

The thickness of the fat layer in a newborn can be assessed under the angles of the shoulder blades. This is a good indicator of a baby's overall health and development.

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What does an abundance of lanugo in a newborn indicate?

The abundance of fluffy hair, or lanugo, in a newborn is often an indicator of prematurity. Full-term babies tend to have less lanugo.

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What is the normal range of hemoglobin in a child aged 1-12 months?

Hemoglobin, the oxygen-carrying protein in red blood cells, has a normal range of 110-130 g/l in babies between 1-12 months old. This supports their rapid growth and development.

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What is the lifespan of red blood cells in newborns?

Red blood cells in newborns have a shorter lifespan of about 12 days compared to adults, who have a lifespan of 100 days. This is normal for newborns and reflects their rapid development.

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Where does hematopoiesis occur by the time of birth?

By the time of birth, hematopoiesis, the process of creating red blood cells, takes place primarily in the bone marrow. This is where new blood cells are made.

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When does the second crossing in the leukocyte formula occur?

The second crossing in the leukocyte formula, reflecting changes in immunity as a child develops, is noted around 4-5 years of age. The predominance of lymphocytes shifts to neutrophils in the blood.

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When does lymphopoiesis begin during intrauterine development?

Lymphopoiesis, the creation of lymphocytes (a type of white blood cell), occurs during the fourth month of intrauterine development. This signifies the development of the immune system before birth.

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What is the Kussmaul-Henzler reflex?

When you stroke a baby's cheek near the corners of their mouth, they turn their head toward the stimulation, open their mouth, and stretch their lips. This is the Kussmaul-Henzler reflex, a normal reflex in newborns.

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Study Notes

Newborn Physiology

  • Meconium passage: Meconium most often passes in a newborn within the first 12 hours, but sometimes up to 72 hours.
  • Gastric mucosa growth: The glands of the gastric mucosa increase in size about 5 times as the child grows.
  • Newborn stomach acidity: The stomach maintains a slightly acidic reaction, maintained by hydrochloric acid.
  • Gallbladder content: A newborn's gallbladder contains relatively low amounts of taurocholic and glycocholic acids, but predominantly cholesterol and small amounts of mucin.
  • Lipase level: The lipase level reaches adult levels around age 17.

Newborn Blood and Urine

  • Normal newborn blood count: A newborn's normal leukocyte count is 10-20x10^9/L.
  • Urine composition shifts: Normally, newborns show changes in urine chemical composition on days 3-4, including increased chlorides and phosphates.
  • Normal urine specific gravity: Normal urine specific gravity in newborns is typically between 1002-1004.

Newborn Kidneys and Development

  • Kidney morphology: Newborn kidneys have weak vascularization and a relatively well-developed cortex compared to underdeveloped medulla.
  • Glomerular filtration: Glomerular filtration rate reaches adult levels by age 5.
  • Kidney function in children: Filtration capacity in children decreases slightly as they age, without reaching adult levels until 17 years old.

Newborn Physical Features

  • Milk teeth eruption: The formula for milk tooth eruption is 2n-4 in newborns.
  • Bone age determination: Bone age is assessed via X-rays of the hands, evaluating bone development.
  • Physiological jaundice: Physiological jaundice occurs due to the physiological destruction of erythrocytes.

Newborn Nervous System

  • Reflexes: A Moro reflex is present in newborns, involving head and limb movement when startled or losing support.
  • Blood pressure differences: Blood pressure in lower extremities and upper extremities can be different in newborns.
  • Heart rate: Normal newborn heart rate is typically within a range of 110-140 beats per minute.
  • Heart shape: Newborn hearts are typically oval-shaped.
  • Kidney development: Kidney development includes well-developed connective tissue and functional capacity.

Newborn Blood Cells

  • Lifespan of red blood cells: Newborn red blood cells have a lifespan averaging 90 days.
  • Hemoglobin content: Hemoglobin content in newborns is typically between 100-140 g/L at the 1-12-month range.
  • Blood morphology at birth: Hematopoietic organs develop at about 18 days after birth.
  • Hematopoiesis: Hematopoiesis occurs in the liver, spleen, bone marrow etc. in newborns.

Additional Information

  • Other factors: The notes also cover various other facts, such as physiological tachycardia, the absence of melanin in newborn skin, and intrauterine development (such as the occurrence of lymphopoiesis), but focus on basic physiology in newborns.

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Description

Test your knowledge on the physiological aspects of newborns, focusing on meconium passage, gastric mucosa growth, and blood composition. This quiz covers essential facts about newborns' digestive and urinary systems. Assess your understanding of normal values and developmental changes in newborns.

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