B3
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Questions and Answers

What physiological effect does excessive contraction of the ciliary muscle indicate?

  • Eye relaxation
  • Eye strain (correct)
  • Vision enhancement
  • Improved focus
  • Which substance is primarily depleted by capsaicin in nerve endings to relieve pain?

  • Dopamine
  • Substance P (correct)
  • Serotonin
  • Endorphins
  • What is the primary function of the TRPV1 receptor?

  • Regulating eye pressure
  • Controlling eye movement
  • Detecting taste
  • Sensing pain and heat (correct)
  • At what temperature does the TRPV1 receptor typically open?

    <p>37-45°C</p> Signup and view all the answers

    Which type of surgery involves reshaping the refractive power of the eye?

    <p>LASEK/LASIK surgery</p> Signup and view all the answers

    Why are birds unaffected by capsaicin?

    <p>They lack the TRPV1 receptor</p> Signup and view all the answers

    Which of the following is responsible for the refractive power of the eye?

    <p>Cornea</p> Signup and view all the answers

    What happens to presynaptic Substance P during prolonged activation by capsaicin?

    <p>It is depleted</p> Signup and view all the answers

    What function do inner hair cells serve in the auditory system?

    <p>They transmit auditory signals to the brain.</p> Signup and view all the answers

    What role do outer hair cells play in relation to inner hair cells?

    <p>They enhance the sensitivity of inner hair cells for sound pitches.</p> Signup and view all the answers

    How many outer hair cells are present compared to inner hair cells?

    <p>3 to 4 times more outer hair cells.</p> Signup and view all the answers

    What part of the cochlea is primarily responsible for supporting the auditory signal's transduction?

    <p>Basilar membrane.</p> Signup and view all the answers

    What anatomical structure aids in decompression of acoustic energy in the cochlea?

    <p>Round window.</p> Signup and view all the answers

    How do nerve fibers from the brain stem interact with outer hair cells?

    <p>They adjust the sensitivity of outer hair cells.</p> Signup and view all the answers

    What characteristic of the fibers in the basilar membrane changes from the base to the helicotrema?

    <p>Length increases and diameter decreases.</p> Signup and view all the answers

    What characterizes Deutan Dichromat vision?

    <p>Presence of only red and blue cones</p> Signup and view all the answers

    Which condition involves green sensitivity shifted toward red?

    <p>Deuteranomaly</p> Signup and view all the answers

    What kind of vibratory movement do the stiff fibers in the basilar membrane exhibit?

    <p>Vibrations like a musical reed.</p> Signup and view all the answers

    What type of potential is used by most neural elements in the retina for signal transmission?

    <p>Electrotonic potentials</p> Signup and view all the answers

    Which cell type in the retina has action potentials and sends signals to the brain?

    <p>Ganglion cells</p> Signup and view all the answers

    What effect does lateral inhibition have on visual processing?

    <p>Enhances visual contrast</p> Signup and view all the answers

    In Protan Dichromat vision, which type of cones are absent?

    <p>Red cones</p> Signup and view all the answers

    Which of the following describes a Protanope?

    <p>Difficulty distinguishing red and green colors</p> Signup and view all the answers

    What is the primary function of horizontal cells in the retina?

    <p>Provide inhibitory feedback and enhance contrast</p> Signup and view all the answers

    What is the primary function of the dorsal column-medial lemniscal system?

    <p>Transmitting touch and vibration information</p> Signup and view all the answers

    Where does the anterolateral system decussate?

    <p>In the spinal cord</p> Signup and view all the answers

    What is a dermatome?

    <p>An area of skin supplied by sensory neurons from a spinal nerve ganglion</p> Signup and view all the answers

    What characterizes the spatial orientation of the anterolateral system?

    <p>Low degree of spatial orientation</p> Signup and view all the answers

    Which area of the body has the most significant representation in the somatosensory cortex?

    <p>Lips</p> Signup and view all the answers

    How does shingles typically manifest in relation to dermatomes?

    <p>The rash occurs in the dermatome of the infected nerve</p> Signup and view all the answers

    What does the sensory homunculus represent?

    <p>The area of the cortex dedicated to sensory perception from different body parts</p> Signup and view all the answers

    Which type of fibers are primarily found in the dorsal column-medial lemniscal system?

    <p>Large myelinated fibers</p> Signup and view all the answers

    What does the Place principle determine in relation to sound?

    <p>The pitch based on the position of hair cells stimulated.</p> Signup and view all the answers

    How is sound intensity expressed in terms of decibels?

    <p>Through a logarithmic scale due to wide intensity range.</p> Signup and view all the answers

    What factors contribute to the pathophysiology of noise-induced hearing loss?

    <p>Loss of stereocilia in outer hair cells.</p> Signup and view all the answers

    What is the significance of a 1-decibel increase in sound intensity?

    <p>It's the minimal change detectable by the human ear.</p> Signup and view all the answers

    Which sound level corresponds to a normal conversation in decibels?

    <p>60 dB</p> Signup and view all the answers

    What indicates the maximum safe exposure duration for sounds at 90 dB?

    <p>2 hours per day without protection.</p> Signup and view all the answers

    What sound level is associated with the quietest sound that humans can hear?

    <p>0 dB</p> Signup and view all the answers

    What occurs when a shotgun blast is heard in terms of hearing protection?

    <p>The reflex offers some protection against sudden loud sounds.</p> Signup and view all the answers

    Study Notes

    Sensory Pathways Overview

    • Sensory information enters the spinal cord through dorsal roots of spinal nerves.
    • Two main pathways exist for sensory afferents: the Anterolateral system and the Dorsal column-medial lemniscal system.

    Dorsal Column-Medial Lemniscal System

    • Comprises large myelinated nerve fibers (30-110 m/sec), specifically A-beta fibers.
    • Utilizes three neurons to transmit signals to the sensory cortex and decussates in the medulla oblongata.
    • Maintains a high degree of spatial orientation, allowing rapid transmission of mechanoreceptor information, including touch and vibration.

    Anterolateral System

    • Contains smaller myelinated and unmyelinated fibers for slower transmission (0.5-40 m/sec), including A-delta and C fibers.
    • Also uses three neurons to reach the sensory cortex but decussates in the spinal cord.
    • Features a lower degree of spatial orientation, capable of transmitting varied modalities such as pain, thermal sensations, crude touch, and pressure.

    Dermatomes

    • Defined as skin areas supplied by sensory neurons from a spinal nerve ganglion.
    • Clinically significant for localizing spinal cord lesions and identifying areas affected by viruses such as varicella zoster.
    • Hosts referred pain, where pain is perceived in a location different from its source.

    Shingles and Dermatome Connection

    • Following a chickenpox infection, varicella zoster virus may reactivate, causing a rash in the affected nerve's dermatome.

    Somatosensory Cortex

    • Located in the postcentral gyrus, exhibiting a highly organized spatial orientation.
    • Each cortex side receives sensory information from the opposite body side.
    • Displays unequal body representation, with the lips having the greatest area, followed by the face and thumb; the trunk has the least representation.

    Sensory Homunculus

    • Represents the proportional space allocated to different parts of the body in the somatosensory cortex.

    Brodmann’s Areas

    • Demonstrates cytoarchitectural organization of neurons in the cerebral cortex, recognized through Nissl stain.

    Substance P and Capsaicin

    • Substance P plays a role in mediating lower back pain, arthritis, and fibromyalgia.
    • Capsaicin, derived from chili peppers, can reduce pain by depleting Substance P from nerve endings, providing pain relief through selective binding to the TRPV1 receptor.

    Phyiscal Anatomy of the Eye

    • White outer layer is continuous with the cornea at the front; suspensory fibers connect the ciliary muscle to the lens.
    • Contains transparent, jellylike tissue with photosensitive cells and 2/3 of the eye’s refractive power.
    • Vision correction procedures like LASEK/LASIK reshape this component for improved visual acuity.

    Color Perception

    • Understanding of deuteranomaly, dichromatism, and protanomalous vision, with associated sensitivities and prevalence statistics among males.

    Retinal Organization and Signal Transmission

    • Processing begins in the retina using electrotonic potentials for signal transmission.
    • Ganglion cells send action potentials to the brain through the optic nerve, responding to light intensity changes and enhancing image contrast through lateral inhibition.

    Auditory Signal Processing

    • Inner hair cells transmit auditory signals, while outer hair cells modulate sensitivity to different pitches.
    • The cochlea’s basilar membrane contains fibers whose stiffness varies by frequency, enabling the perception of pitch.

    Sound Frequency and Amplitude

    • The place principle describes how different sound frequencies stimulate specific basilar membrane locations.
    • Sound intensity is expressed in decibels, reflecting the logarithm of actual sound intensity, where 10-fold increases signify a bel.

    Noise-Induced Hearing Loss

    • Prevalent condition characterized by decreased stereocilia stiffness and loss caused by exposure to high decibel levels.
    • Recommendations for maximum sound exposure durations to prevent hearing damage based on decibel levels.

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