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Questions and Answers
In the study that used fMRI to assess awareness in a patient with PVS, what brain area was activated when the patient was asked to imagine playing tennis?
In the study that used fMRI to assess awareness in a patient with PVS, what brain area was activated when the patient was asked to imagine playing tennis?
A patient who recovers from PVS after 20 months following a car accident, typically exhibits which of the following?
A patient who recovers from PVS after 20 months following a car accident, typically exhibits which of the following?
Phantom limb pain is often felt most intensely in which area of the missing limb?
Phantom limb pain is often felt most intensely in which area of the missing limb?
What is suggested to be the primary cause of the pain sensation experienced in phantom limbs?
What is suggested to be the primary cause of the pain sensation experienced in phantom limbs?
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What led to the shift in terminology from “Persistent Vegetative State” (PVS) to Unresponsive Wakefulness Syndrome’?
What led to the shift in terminology from “Persistent Vegetative State” (PVS) to Unresponsive Wakefulness Syndrome’?
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What is the main idea behind the 'homunculus problem'?
What is the main idea behind the 'homunculus problem'?
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According to Crick and Koch, how is the problem of infinite regress in consciousness avoided?
According to Crick and Koch, how is the problem of infinite regress in consciousness avoided?
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Which of the following best describes the 'bright spot' metaphor in the Global Workspace Theory (GWT)?
Which of the following best describes the 'bright spot' metaphor in the Global Workspace Theory (GWT)?
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In GWT, what is the role of the 'backstage'?
In GWT, what is the role of the 'backstage'?
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According to GWT, what is the approximate capacity of the Global Workspace (the number of items dealt with consciously at a time)?
According to GWT, what is the approximate capacity of the Global Workspace (the number of items dealt with consciously at a time)?
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What does the symbol Φ (phi) represent in Integrated Information Theory (IIT)?
What does the symbol Φ (phi) represent in Integrated Information Theory (IIT)?
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According to IIT, how is consciousness viewed?
According to IIT, how is consciousness viewed?
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Why is a high megapixel camera not conscious according to IIT, despite having many pixels?
Why is a high megapixel camera not conscious according to IIT, despite having many pixels?
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What is the primary focus of studies on Neural Correlates of Consciousness (NCC)?
What is the primary focus of studies on Neural Correlates of Consciousness (NCC)?
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When a correlation between neural events and conscious experience is found, what must be considered?
When a correlation between neural events and conscious experience is found, what must be considered?
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In the study of NCC using the Necker cube, what remains constant while the conscious state changes?
In the study of NCC using the Necker cube, what remains constant while the conscious state changes?
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What is the key characteristic of 'binocular rivalry' that makes it useful for studying NCC?
What is the key characteristic of 'binocular rivalry' that makes it useful for studying NCC?
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According to the content provided, where does the activity related to perceptual flips in binocular rivalry initially originate?
According to the content provided, where does the activity related to perceptual flips in binocular rivalry initially originate?
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What is the relationship between the proportion of neurons syncing with image flips and their location in the brain?
What is the relationship between the proportion of neurons syncing with image flips and their location in the brain?
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Which of the following best describes the condition of locked-in syndrome?
Which of the following best describes the condition of locked-in syndrome?
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What is the primary mode of communication for individuals with locked-in syndrome, as described in the provided content?
What is the primary mode of communication for individuals with locked-in syndrome, as described in the provided content?
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Patient GY, who experienced blindness in one hemifield due to V1 damage, could consciously perceive an object under which condition?
Patient GY, who experienced blindness in one hemifield due to V1 damage, could consciously perceive an object under which condition?
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Based on the case of patient GY, what is the main area in the brain associated with conscious perception of motion?
Based on the case of patient GY, what is the main area in the brain associated with conscious perception of motion?
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If activity increased in V5 and nowhere else in GY's brain when he consciously perceived motion, what does this imply about V5?
If activity increased in V5 and nowhere else in GY's brain when he consciously perceived motion, what does this imply about V5?
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According to the information provided, what is the temporal relationship between the conscious perception of color and motion?
According to the information provided, what is the temporal relationship between the conscious perception of color and motion?
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Why do we perceive color and motion to be synchronized despite the difference in processing time?
Why do we perceive color and motion to be synchronized despite the difference in processing time?
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When discussing consciousness using the analogy of a 'theatre of the mind,' the 'mental screen' is where?
When discussing consciousness using the analogy of a 'theatre of the mind,' the 'mental screen' is where?
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What was Roger Shepard’s key finding regarding mental rotation experiments?
What was Roger Shepard’s key finding regarding mental rotation experiments?
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Which specific brain area is implicated in mental rotation according to the provided text?
Which specific brain area is implicated in mental rotation according to the provided text?
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Why might a sensation of touch on a phantom hand sometimes be perceived as touch on the face?
Why might a sensation of touch on a phantom hand sometimes be perceived as touch on the face?
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According to the lecture, which of the following statements is most accurate regarding pain perception?
According to the lecture, which of the following statements is most accurate regarding pain perception?
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What was the key principle behind Ramachandran’s treatment for phantom limb pain?
What was the key principle behind Ramachandran’s treatment for phantom limb pain?
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Which of these best describes the Global Workspace Theory concerning consciousness?
Which of these best describes the Global Workspace Theory concerning consciousness?
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What is the significance of the discovery of giant neurons in the claustrum concerning consciousness?
What is the significance of the discovery of giant neurons in the claustrum concerning consciousness?
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What are the implications of Semir Zeki's findings about the 'disunity of consciousness'?
What are the implications of Semir Zeki's findings about the 'disunity of consciousness'?
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Damage to which of the following brain areas would most likely result in visual motion blindness (akinetopsia)?
Damage to which of the following brain areas would most likely result in visual motion blindness (akinetopsia)?
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According to the lecture, what is the concept of 'micro-consciousness' referring to?
According to the lecture, what is the concept of 'micro-consciousness' referring to?
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What is a key characteristic of a camera sensor's photodiodes?
What is a key characteristic of a camera sensor's photodiodes?
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What is the main idea of Penrose's theory regarding consciousness and computation?
What is the main idea of Penrose's theory regarding consciousness and computation?
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According to Richard Feynman, how should we perceive the behavior of elementary particles?
According to Richard Feynman, how should we perceive the behavior of elementary particles?
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According to Penrose, where do quantum processes that lead to consciousness arise?
According to Penrose, where do quantum processes that lead to consciousness arise?
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What is the concept of superposition as described in the text?
What is the concept of superposition as described in the text?
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What is the purpose of Schrodinger's cat thought experiment?
What is the purpose of Schrodinger's cat thought experiment?
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What is the 'psi-function' referred to in the context of Schrödinger's cat?
What is the 'psi-function' referred to in the context of Schrödinger's cat?
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Why does the Copenhagen interpretation pose a question concerning superposition in the macroscopic world?
Why does the Copenhagen interpretation pose a question concerning superposition in the macroscopic world?
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Flashcards
Persistent Vegetative State (PVS)
Persistent Vegetative State (PVS)
A condition where a person appears to be awake but shows no signs of awareness or consciousness.
Anterograde Amnesia
Anterograde Amnesia
A type of amnesia where a person cannot form new memories after the onset of the condition.
Phantom Limb
Phantom Limb
The sensation of a missing limb still being present after amputation.
Cortical Areas Representing the Missing Limb
Cortical Areas Representing the Missing Limb
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Brain Interpretation of Nerve Signals
Brain Interpretation of Nerve Signals
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Pain Perception
Pain Perception
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Anterior Cingulate Cortex (ACC)
Anterior Cingulate Cortex (ACC)
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Mirror Therapy for Phantom Pain
Mirror Therapy for Phantom Pain
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Claustrum
Claustrum
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Distributed Processing of Consciousness
Distributed Processing of Consciousness
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Integrated Information Theory (IIT)
Integrated Information Theory (IIT)
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Micro-Consciousness
Micro-Consciousness
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Neural Correlates of Consciousness (NCC)
Neural Correlates of Consciousness (NCC)
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Locked-in Syndrome
Locked-in Syndrome
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Minimally Conscious State (MCS)
Minimally Conscious State (MCS)
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Binocular Rivalry
Binocular Rivalry
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Visual Cortex (V1)
Visual Cortex (V1)
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Higher Cortical Centers
Higher Cortical Centers
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V5
V5
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Blindsight
Blindsight
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Perceptual Synchronization
Perceptual Synchronization
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Cartesian Theatre
Cartesian Theatre
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Mental Rotation
Mental Rotation
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Mental Rotation Correlation
Mental Rotation Correlation
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Right Posterior Parietal Lobe
Right Posterior Parietal Lobe
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The Observer
The Observer
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Global Workspace Theory (GWT)
Global Workspace Theory (GWT)
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Φ (Phi)
Φ (Phi)
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The Hard Problem of Consciousness
The Hard Problem of Consciousness
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Infinite Regress
Infinite Regress
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Crick and Koch's Solution to the Infinite Regress
Crick and Koch's Solution to the Infinite Regress
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Consciousness as a Global Workspace
Consciousness as a Global Workspace
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Consciousness as Integrated Information
Consciousness as Integrated Information
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Superposition
Superposition
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Microtubules
Microtubules
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Copenhagen Interpretation
Copenhagen Interpretation
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Camera Sensor as a Collection of Photodiodes
Camera Sensor as a Collection of Photodiodes
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Penrose's Quantum Theory of Consciousness
Penrose's Quantum Theory of Consciousness
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Consciousness vs. Computation
Consciousness vs. Computation
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Quantum Theory
Quantum Theory
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Feynman's Explanation of Quantum Behavior
Feynman's Explanation of Quantum Behavior
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Study Notes
Neural Correlates of Consciousness (NCC)
- NCC does not attempt to solve the "hard problem" of qualia (subjective experience).
- It investigates neural processes and correlates them with conscious experience.
- Causality is a crucial consideration when correlating neural events and conscious experience. Possible relationships include: neural event causing conscious experience; neural event being caused by conscious experience; or something else causing both.
- A confound exists between neural activity coding a color stimulus and coding the conscious experience of color.
Studying NCC
- Keeping the stimulus constant while recording brain events as conscious states change is a method.
- Examples of the method are Necker cubes and binocular rivalry.
- V1 activity changes in sync with percept flip during binocular rivalry and originates in monocular neurons.
- Higher cortical centers are also involved.
Single-Cell Recordings in Monkeys
- Neural activity is recorded while monkeys report what they see.
- Neurons are active only when the monkeys report one of the two percepts being experienced.
Increasing Proportion of Neurons Syncing
- Proportion of neurons syncing with image flips increases as the brain areas get higher, e.g., V1/V2=20%; V4/V5 =40%; inferior temporal cortex (IT) & superior temporal sulcus (STS) =90%.
Disorders of Consciousness
- Locked-in Syndrome: Damage to the brainstem (accident, disease or stroke). Higher functioning areas are spared (except eyes). Communication via blinking or computer interface.
- Persistent Vegetative State (PVS): Wakefulness without awareness. PVS is between coma and minimally conscious states. Caused by damage to higher brain areas (trauma, virus, tumor). Brainstem is generally intact. A PVS status of more than 4 weeks is persistent PVS. PVS patients can be chronically awake but show regular sleep-wake cycles and REM sleep (though REM sleep duration is shorter than normal controls). There is no correlation between REM sleep duration and likelihood of recovery.
- Minimally Conscious State (MCS): Inconsistent signs of consciousness(may understand simple commands).
- Electrical stimulation to PVS patients shows activation of brainstem, thalamus and primary somatosensory cortex, but higher brain centers don't respond. Dissociation between primary sensory areas and fronto-parietal network is a defining feature of PVS.
- Awareness detection in PVS can be checked through spoken instructions (e.g., imagine playing tennis or walking through rooms).
- Studying PVS patients shows that patients may understand and respond to commands using brain activity, and that a clear act of intent is expressed through their decision to cooperate with researchers. PVS is sometimes referred to as Unresponsive Wakefulness Syndrome (UWS), a more relevant descriptor.
- Terri Schiavo case: Illustrates debate regarding PVS and end-of-life care.
Phantom Limbs
- Over 90% of individuals experience phantom limbs after losing an arm or leg.
- Onsets can occur the same day, or develop days/weeks later.
- Phantom limbs can persist for years/decades.
- Phantom limb pain includes sensations like cramping, clenching hands and other sensations; sensations often occur in the parts of the body farthest from the body, e.g., foot on an amputated leg.
- The exact cause of pain is unclear but may be a response to mixed signals to the brain.
- This leads to the brain interpreting that the limb is still there.
- Cortical areas representing the missing limb may adapt; e.g., face area may take over the hand area of the somatosensory cortex.
Neural Correlates of Pain
- Pain perception is always subjective (qualia).
- Increased activity in the anterior cingulate cortex (ACC) correlates with more intense pain.
Ramachandran's Treatment
- Ramachandran treated patients with phantom limb pain.
- The treatment involved patients observing a reflection of their normal hand and being directed to move both hands together.
- Visual feedback reduced phantom limb pain.
Virtual Arms
- Virtual arms can also ease phantom pain.
- Patients can see and move a virtual arm.
- Electric signals from amputated arm muscles are sent to a computer and create real-time movement of the virtual arm.
Theories of Consciousness (General)
- The brain areas involved in consciousness are determined not by a single center, but by distributed processing, feedback loops, and complex, dynamic patterns of cell assemblies and interactions between distant areas (corticocortical & corticothalamic). Though interactions are abundant, no single central location exists.
- The disunity of consciousness is the concept that different conscious processes occur at different locations and times in the brain.
Global Workspace Theory (GWT)
- Consciousness is like a "bright spot" on a stage, and a spotlight of attention directs it to different actors (ideas, feelings, etc.).
- Actors in the scene or workspace compete for this access to consciousness.
- Actors compete to occupy the "bright spot" on stage, while others are in the backstage or fringe of consciousness.
- Fringe area is where working memory is stored so these memories can enter and leave the spotlight.
Integrated Information Theory (IIT)
- Consciousness is graded with a measure (Φ, phi) indicating the integration of information. Higher phi values indicate higher integration of information.
Quantum Physics Theory of Consciousness
- Consciousness may arise from quantum processes in microtubules (tiny tube-like proteins in all cells).
- Quantum states may underlie subjective experience (qualia).
- The interpretation of superposition states, and their relation to free will, is a major concept associated with the quantum theory of consciousness. The Copenhagen interpretation focuses on the collapse into a single state when observed, while the many-worlds interpretation holds that superposition is maintained in a vast number of entangled realities, all with alternate outcomes; each possible outcome becomes its own reality. Criticism of the theory is frequent for its inability to explain phenomena relating to macroscopic experiences from properties of microtubules or their underlying quantum physics.
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Description
Test your knowledge on neuroscience, particularly in the context of consciousness, persistent vegetative state, and phantom limb sensations. This quiz covers various theories and significant findings in the study of brain activity and awareness. Challenge yourself with questions that delve into advanced topics in neurobiology.