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What is the primary role of sensory cells in the nervous system?
What is the primary role of sensory cells in the nervous system?
To detect and transmit sensory stimuli to the nervous system.
How do graded potentials differ from action potentials?
How do graded potentials differ from action potentials?
Graded potentials vary in magnitude and can be depolarizing or hyperpolarizing, whereas action potentials are all-or-nothing and have a fixed amplitude.
What is the function of neurotransmitters at synapses?
What is the function of neurotransmitters at synapses?
To transmit signals across the synaptic cleft to adjacent neurons or target cells.
Explain the significance of action potentials in nerve cell axons.
Explain the significance of action potentials in nerve cell axons.
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Why do action potentials propagate in one direction along an axon?
Why do action potentials propagate in one direction along an axon?
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What role do neuroglia play in the nervous system?
What role do neuroglia play in the nervous system?
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How do synapses contribute to neuronal circuits?
How do synapses contribute to neuronal circuits?
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What is the importance of muscle stretch receptors in the nervous system?
What is the importance of muscle stretch receptors in the nervous system?
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What causes the rapid influx of Na+ during an action potential?
What causes the rapid influx of Na+ during an action potential?
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What occurs at the peak of the action potential concerning Na+ channels?
What occurs at the peak of the action potential concerning Na+ channels?
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Explain the mechanism behind the efflux of K+ during repolarization.
Explain the mechanism behind the efflux of K+ during repolarization.
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What role does the Na+/K+ pump play after an action potential?
What role does the Na+/K+ pump play after an action potential?
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Why do action potentials propagate in one direction in nerve cell axons?
Why do action potentials propagate in one direction in nerve cell axons?
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What role do muscle stretch receptors play in sensing the environment?
What role do muscle stretch receptors play in sensing the environment?
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Describe how neurotransmitters are involved in sensory neuron activation.
Describe how neurotransmitters are involved in sensory neuron activation.
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Explain the difference between graded potentials and action potentials.
Explain the difference between graded potentials and action potentials.
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What mechanism allows neurotransmitters to bind to postsynaptic cells?
What mechanism allows neurotransmitters to bind to postsynaptic cells?
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How does stimulus strength affect the generation of graded potentials in sensory cells?
How does stimulus strength affect the generation of graded potentials in sensory cells?
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What is the significance of axon diameter in the speed of nerve impulse transmission?
What is the significance of axon diameter in the speed of nerve impulse transmission?
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Identify the overall function of sensory cells in the nervous system.
Identify the overall function of sensory cells in the nervous system.
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What is the primary function of ion channels in nerve impulse transmission?
What is the primary function of ion channels in nerve impulse transmission?
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How are graded potentials generated in the cell body of a neuron?
How are graded potentials generated in the cell body of a neuron?
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Describe how sensory systems utilize specific receptor cells.
Describe how sensory systems utilize specific receptor cells.
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What initiates the opening of ligand-gated Na+ channels in sensory cells?
What initiates the opening of ligand-gated Na+ channels in sensory cells?
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Describe the change in membrane potential during Na+ influx.
Describe the change in membrane potential during Na+ influx.
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What is the consequence of activating gated Na+ channels in sensory cells?
What is the consequence of activating gated Na+ channels in sensory cells?
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Differentiate between 'ligand-gated' and 'voltage-gated' ion channels.
Differentiate between 'ligand-gated' and 'voltage-gated' ion channels.
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What role do Na+ ions play during the generation of a graded potential?
What role do Na+ ions play during the generation of a graded potential?
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In terms of membrane potential, what typically precedes the entrance of Na+ ions?
In terms of membrane potential, what typically precedes the entrance of Na+ ions?
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Explain how a ligand such as a hormone might affect sensory perception.
Explain how a ligand such as a hormone might affect sensory perception.
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What is the primary effect of depolarization in sensory cells?
What is the primary effect of depolarization in sensory cells?
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How does the influx of Na+ differ from the influx of Ca2+ in sensory cells?
How does the influx of Na+ differ from the influx of Ca2+ in sensory cells?
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Why is the rapid increase in membrane potential important for neural communication?
Why is the rapid increase in membrane potential important for neural communication?
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How does the binding of a ligand lead to the opening of Na+ channels?
How does the binding of a ligand lead to the opening of Na+ channels?
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What occurs after the influx of Na+ increases membrane potential?
What occurs after the influx of Na+ increases membrane potential?
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Explain the role of Ca2+ in neurotransmitter release.
Explain the role of Ca2+ in neurotransmitter release.
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What happens when a sensory cell is stimulated?
What happens when a sensory cell is stimulated?
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Describe the importance of the -55 mV threshold in axons.
Describe the importance of the -55 mV threshold in axons.
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How does the frequency of action potentials relate to the stimulus strength?
How does the frequency of action potentials relate to the stimulus strength?
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What role do NT receptors play on the post-synaptic cell?
What role do NT receptors play on the post-synaptic cell?
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When does a nerve impulse travel along the axon?
When does a nerve impulse travel along the axon?
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What determines the directionality of a nerve impulse?
What determines the directionality of a nerve impulse?
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What is the relationship between graded potentials and action potentials?
What is the relationship between graded potentials and action potentials?
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Study Notes
Neuron Overview
- Sensory cells receive information from the external or internal environment and release neurotransmitters.
Graded Potentials and Action Potentials
- Graded potentials are changes in membrane potential that are proportional to the strength of the stimulus. They are short-distance signals via diffusion.
- Action potentials are rapid, long-distance signals that travel along axons. They are “all-or-none” events, meaning they either fire or they don't.
Ion Channels in Nerve Impulse Transmission
- Sensory cells have ligand-gated sodium (Na+) channels that open when a stimulus binds to them. This causes Na+ to rush into the cell and increase membrane potential.
- This rapid influx of Na+ triggers a graded potential.
- The graded potential activates voltage-gated calcium (Ca2+) channels in the cell membrane.
- Ca2+ channels open and Ca2+ rushes into the cell.
- The increase in Ca2+ causes neurotransmitter (NT) vesicles to fuse with the presynaptic membrane and release NT into the synapse.
- NT travels by diffusion to the postsynaptic cell.
Action Potential Propagation
- When NT binds to receptors on the dendrites or cell body of a nerve cell, it generates a graded potential at the axon hillock.
- If the membrane potential at the axon hillock reaches the threshold of -55mV, an action potential fires and travels along the axon.
Threshold Potential
- Threshold potential is the minimum membrane potential that must be reached for an action potential to fire.
- If the threshold potential is not reached, no action potential is generated.
- If threshold potential is reached, it triggers a low frequency of action potentials traveling along the axon.
- If a sustained threshold potential is maintained, it triggers a high frequency of action potentials traveling along the axon.
Synaptic Transmission
- The arrival of an action potential at the nerve terminal triggers the release of NT into the synapse.
- This process continues the signal and influences the next neuron in the circuit.
Action Potential
- The influx of Na+ is rapid during an action potential (AP) due to the large sodium gradient and a large electrical gradient.
- The sodium channels close at the peak of the AP, which is at approximately +30mV.
- The potassium channels open at +30mV leading to the efflux of K+ decreasing the membrane potential to -90mV.
- Potassium efflux is rapid due to the large potassium gradient and a large electrical gradient.
- The Na+/K+ pump is involved in resetting the resting membrane potential (RMP) to -70mV.
Nerve Cell Axon
- Action Potentials propagate in one direction due to the refractory period, during which the membrane is less likely to fire another action potential.
- The myelin sheath, produced by neuroglia, acts as an insulator for the axon, increasing the speed of action potential propagation.
Synaptic Transmission
- Synaptic transmission is the process of communication between neurons at a synapse.
- It involves the release of neurotransmitters from the presynaptic neuron, which bind to receptors on the postsynaptic neuron.
- Synapses play a critical role in neuronal circuits, enabling complex neural processing and communication.
Local Anaesthetics and Neurotoxins
- Local anaesthetics block sodium channels, preventing the influx of sodium and thus the generation of action potentials.
- Neurotoxins, like tetrodotoxin, also block sodium channels, leading to paralysis.
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Description
Explore the intricacies of neuron functions including sensory cell responses, graded and action potentials, and ion channels involved in nerve impulse transmission. This quiz covers essential concepts for understanding how neurons communicate and process information.