Neuron Overview and Signal Transmission
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Questions and Answers

What is the primary role of sensory cells in the nervous system?

To detect and transmit sensory stimuli to the nervous system.

How do graded potentials differ from action potentials?

Graded potentials vary in magnitude and can be depolarizing or hyperpolarizing, whereas action potentials are all-or-nothing and have a fixed amplitude.

What is the function of neurotransmitters at synapses?

To transmit signals across the synaptic cleft to adjacent neurons or target cells.

Explain the significance of action potentials in nerve cell axons.

<p>Action potentials allow for the rapid transmission of electrical signals along the axon to communicate with other neurons or muscles.</p> Signup and view all the answers

Why do action potentials propagate in one direction along an axon?

<p>They propagate unidirectionally due to the refractory period that follows the depolarization, preventing the signal from traveling backward.</p> Signup and view all the answers

What role do neuroglia play in the nervous system?

<p>Neuroglia support and protect neurons, maintaining homeostasis and forming myelin sheaths around axons.</p> Signup and view all the answers

How do synapses contribute to neuronal circuits?

<p>Synapses allow for communication between neurons, enabling the formation of complex circuits that process information.</p> Signup and view all the answers

What is the importance of muscle stretch receptors in the nervous system?

<p>Muscle stretch receptors provide feedback about muscle length and tension, aiding in proprioception and reflex actions.</p> Signup and view all the answers

What causes the rapid influx of Na+ during an action potential?

<p>The influx of Na+ is extremely rapid due to a large concentration gradient and a strong electrical gradient.</p> Signup and view all the answers

What occurs at the peak of the action potential concerning Na+ channels?

<p>Na+ channels close at the peak of the action potential, which is +30 mV.</p> Signup and view all the answers

Explain the mechanism behind the efflux of K+ during repolarization.

<p>The efflux of K+ is rapid because of a large K+ concentration gradient and a significant electrical gradient.</p> Signup and view all the answers

What role does the Na+/K+ pump play after an action potential?

<p>The Na+/K+ pump helps reset the resting membrane potential (RMP) back to -70 mV.</p> Signup and view all the answers

Why do action potentials propagate in one direction in nerve cell axons?

<p>Action potentials propagate in one direction due to the refractory period of the previously depolarized section of the axon.</p> Signup and view all the answers

What role do muscle stretch receptors play in sensing the environment?

<p>Muscle stretch receptors detect changes in muscle length, providing information about the internal environment.</p> Signup and view all the answers

Describe how neurotransmitters are involved in sensory neuron activation.

<p>Neurotransmitters are released by sensory cells when activated, triggering graded potentials in adjacent neurons.</p> Signup and view all the answers

Explain the difference between graded potentials and action potentials.

<p>Graded potentials are localized changes in membrane potential, while action potentials are rapid, large-scale changes that propagate along axons.</p> Signup and view all the answers

What mechanism allows neurotransmitters to bind to postsynaptic cells?

<p>Neurotransmitters diffuse across the synaptic cleft and bind to specific receptors on the postsynaptic cell.</p> Signup and view all the answers

How does stimulus strength affect the generation of graded potentials in sensory cells?

<p>An increase in stimulus strength leads to a greater increase in membrane potential, resulting in stronger graded potentials.</p> Signup and view all the answers

What is the significance of axon diameter in the speed of nerve impulse transmission?

<p>Larger diameter axons allow for faster transmission of action potentials due to reduced resistance to ion flow.</p> Signup and view all the answers

Identify the overall function of sensory cells in the nervous system.

<p>Sensory cells detect environmental stimuli and convert them into electrical signals for transmission to the nervous system.</p> Signup and view all the answers

What is the primary function of ion channels in nerve impulse transmission?

<p>Ion channels facilitate the movement of ions across nerve cell membranes, crucial for generating action potentials.</p> Signup and view all the answers

How are graded potentials generated in the cell body of a neuron?

<p>Graded potentials in the cell body are created by synaptic inputs from dendrites that alter the membrane potential.</p> Signup and view all the answers

Describe how sensory systems utilize specific receptor cells.

<p>Sensory systems employ specialized receptor cells that respond to specific stimuli, such as sweet, salty, or light.</p> Signup and view all the answers

What initiates the opening of ligand-gated Na+ channels in sensory cells?

<p>The binding of a ligand, such as sugar, a drug, or a hormone, to the channel initiates the opening of ligand-gated Na+ channels.</p> Signup and view all the answers

Describe the change in membrane potential during Na+ influx.

<p>The influx of Na+ causes the membrane potential to increase rapidly, resulting in depolarization.</p> Signup and view all the answers

What is the consequence of activating gated Na+ channels in sensory cells?

<p>The activation leads to a rapid influx of Na+, which generates a graded potential.</p> Signup and view all the answers

Differentiate between 'ligand-gated' and 'voltage-gated' ion channels.

<p>Ligand-gated channels open in response to specific molecules binding to them, while voltage-gated channels open in response to changes in membrane potential.</p> Signup and view all the answers

What role do Na+ ions play during the generation of a graded potential?

<p>Na+ ions contribute to the depolarization of the cell when they rush in, creating a graded potential.</p> Signup and view all the answers

In terms of membrane potential, what typically precedes the entrance of Na+ ions?

<p>Before Na+ ions enter, the membrane potential is generally at a resting level around -70 mV.</p> Signup and view all the answers

Explain how a ligand such as a hormone might affect sensory perception.

<p>When a hormone binds to the ligand-gated Na+ channels, it triggers the opening of these channels, leading to changes in sensory perception through graded potentials.</p> Signup and view all the answers

What is the primary effect of depolarization in sensory cells?

<p>The primary effect of depolarization in sensory cells is the generation of action potentials or graded potentials, which convey sensory information.</p> Signup and view all the answers

How does the influx of Na+ differ from the influx of Ca2+ in sensory cells?

<p>The influx of Na+ primarily causes depolarization, while Ca2+ influx is often involved in signaling pathways and neurotransmitter release.</p> Signup and view all the answers

Why is the rapid increase in membrane potential important for neural communication?

<p>The rapid increase in membrane potential is critical for transmitting signals quickly and efficiently within the nervous system.</p> Signup and view all the answers

How does the binding of a ligand lead to the opening of Na+ channels?

<p>The ligand binds to the channel, causing the ligand-gated Na+ channel to open, which allows Na+ to rush into the cell.</p> Signup and view all the answers

What occurs after the influx of Na+ increases membrane potential?

<p>The increased membrane potential activates the voltage-gated Ca2+ channels, leading to Ca2+ rushing into the cell.</p> Signup and view all the answers

Explain the role of Ca2+ in neurotransmitter release.

<p>Ca2+ diffuses across the entire cell and causes neurotransmitter vesicles to fuse with the presynaptic membrane and release their contents into the synapse.</p> Signup and view all the answers

What happens when a sensory cell is stimulated?

<p>The sensory cell generates graded potentials that lead to the release of neurotransmitters in response to the stimulus.</p> Signup and view all the answers

Describe the importance of the -55 mV threshold in axons.

<p>If the membrane potential reaches -55 mV, action potentials are generated and propagated along the axon.</p> Signup and view all the answers

How does the frequency of action potentials relate to the stimulus strength?

<p>A larger stimulus can maintain the threshold of -55 mV, resulting in a high frequency of action potentials.</p> Signup and view all the answers

What role do NT receptors play on the post-synaptic cell?

<p>NT receptors are ligand-gated Na+ channels that, upon binding neurotransmitters, facilitate Na+ influx into the post-synaptic cell.</p> Signup and view all the answers

When does a nerve impulse travel along the axon?

<p>A nerve impulse travels when the membrane potential reaches the threshold of -55 mV.</p> Signup and view all the answers

What determines the directionality of a nerve impulse?

<p>The nerve impulse travels in one direction due to the refractory period in the previously depolarized segment of the axon.</p> Signup and view all the answers

What is the relationship between graded potentials and action potentials?

<p>Graded potentials contribute to the membranous changes that can generate action potentials if the threshold is reached.</p> Signup and view all the answers

Study Notes

Neuron Overview

  • Sensory cells receive information from the external or internal environment and release neurotransmitters.

Graded Potentials and Action Potentials

  • Graded potentials are changes in membrane potential that are proportional to the strength of the stimulus. They are short-distance signals via diffusion.
  • Action potentials are rapid, long-distance signals that travel along axons. They are “all-or-none” events, meaning they either fire or they don't.

Ion Channels in Nerve Impulse Transmission

  • Sensory cells have ligand-gated sodium (Na+) channels that open when a stimulus binds to them. This causes Na+ to rush into the cell and increase membrane potential.
  • This rapid influx of Na+ triggers a graded potential.
  • The graded potential activates voltage-gated calcium (Ca2+) channels in the cell membrane.
  • Ca2+ channels open and Ca2+ rushes into the cell.
  • The increase in Ca2+ causes neurotransmitter (NT) vesicles to fuse with the presynaptic membrane and release NT into the synapse.
  • NT travels by diffusion to the postsynaptic cell.

Action Potential Propagation

  • When NT binds to receptors on the dendrites or cell body of a nerve cell, it generates a graded potential at the axon hillock.
  • If the membrane potential at the axon hillock reaches the threshold of -55mV, an action potential fires and travels along the axon.

Threshold Potential

  • Threshold potential is the minimum membrane potential that must be reached for an action potential to fire.
  • If the threshold potential is not reached, no action potential is generated.
  • If threshold potential is reached, it triggers a low frequency of action potentials traveling along the axon.
  • If a sustained threshold potential is maintained, it triggers a high frequency of action potentials traveling along the axon.

Synaptic Transmission

  • The arrival of an action potential at the nerve terminal triggers the release of NT into the synapse.
  • This process continues the signal and influences the next neuron in the circuit.

Action Potential

  • The influx of Na+ is rapid during an action potential (AP) due to the large sodium gradient and a large electrical gradient.
  • The sodium channels close at the peak of the AP, which is at approximately +30mV.
  • The potassium channels open at +30mV leading to the efflux of K+ decreasing the membrane potential to -90mV.
  • Potassium efflux is rapid due to the large potassium gradient and a large electrical gradient.
  • The Na+/K+ pump is involved in resetting the resting membrane potential (RMP) to -70mV.

Nerve Cell Axon

  • Action Potentials propagate in one direction due to the refractory period, during which the membrane is less likely to fire another action potential.
  • The myelin sheath, produced by neuroglia, acts as an insulator for the axon, increasing the speed of action potential propagation.

Synaptic Transmission

  • Synaptic transmission is the process of communication between neurons at a synapse.
  • It involves the release of neurotransmitters from the presynaptic neuron, which bind to receptors on the postsynaptic neuron.
  • Synapses play a critical role in neuronal circuits, enabling complex neural processing and communication.

Local Anaesthetics and Neurotoxins

  • Local anaesthetics block sodium channels, preventing the influx of sodium and thus the generation of action potentials.
  • Neurotoxins, like tetrodotoxin, also block sodium channels, leading to paralysis.

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Explore the intricacies of neuron functions including sensory cell responses, graded and action potentials, and ion channels involved in nerve impulse transmission. This quiz covers essential concepts for understanding how neurons communicate and process information.

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