Neurology Quiz on ALS and Related Conditions
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Questions and Answers

What is an indication that distinguishes early-onset postural instability from idiopathic Parkinson disease?

  • Spasticity and hyperreflexia (correct)
  • Proximal muscle atrophy
  • Presence of cognitive decline
  • Limb weakness
  • Which of the following symptoms is most likely associated with amyotrophic lateral sclerosis (ALS)?

  • Severe joint pain
  • Progressive distal limb weakness (correct)
  • Cognitive impairment
  • Tremors in hands
  • Which combination of symptoms suggests a diagnosis of ALS in the described patient?

  • Spasticity and tremors
  • Atrophy and fasciculations (correct)
  • Loss of coordination and fatigue
  • Resting tremor and bradykinesia
  • What age group is represented in the case of the patient showing signs consistent with ALS?

    <p>50-60 years</p> Signup and view all the answers

    What combination of neurological signs does the patient in the case exhibit?

    <p>Both upper and lower motor neuron signs</p> Signup and view all the answers

    What symptom is most likely associated with L5 nerve root compression in this patient?

    <p>Weakness in foot dorsiflexion/toe extension</p> Signup and view all the answers

    Which imaging technique is utilized for diagnosing the condition related to spinal dysraphism?

    <p>MRI of the spine</p> Signup and view all the answers

    What is the most likely age and symptom presentation of the patient described?

    <p>34-year-old with sudden-onset back pain</p> Signup and view all the answers

    The sensory loss described in the patient is noted over which area?

    <p>Dorsum of the foot</p> Signup and view all the answers

    What condition is most commonly associated with stretch-induced dysfunction in the context described?

    <p>Spinal dysraphism</p> Signup and view all the answers

    What is the most appropriate management for a 79-year-old woman with recurrent falls and ventriculomegaly?

    <p>High-volume lumbar puncture</p> Signup and view all the answers

    Which diagnostic test is essential for confirming Friedreich ataxia in a 14-year-old girl presenting with lower limb weakness?

    <p>Genetic testing</p> Signup and view all the answers

    What symptom typifies the progression of Parkinson disease dementia in a 74-year-old man?

    <p>Visual hallucinations</p> Signup and view all the answers

    In the case of a 67-year-old man with urinary retention and bilateral leg numbness post-neuraxial anesthesia, what is the most appropriate imaging study?

    <p>MRI of the lumbosacral spine</p> Signup and view all the answers

    What treatment should be initiated for a 65-year-old woman with symptoms suggesting depression-related cognitive impairment?

    <p>Escitalopram</p> Signup and view all the answers

    What test is crucial for confirming herpes simplex encephalitis in a 26-year-old with altered behavior?

    <p>HSV polymerase chain reaction</p> Signup and view all the answers

    Which characteristic symptom is typically seen in the early stages of Alzheimer disease?

    <p>Progressive memory deficits</p> Signup and view all the answers

    For the 17-year-old primigravida presenting with symptoms of idiopathic intracranial hypertension, what procedure is next after MRI?

    <p>Lumbar puncture</p> Signup and view all the answers

    What is the most likely diagnosis for a 26-year-old man presenting with upward gaze deviation and rigidity after using haloperidol?

    <p>Acute dystonia</p> Signup and view all the answers

    Which medication is commonly used to treat acute dystonia resulting from antipsychotic use?

    <p>Benztropine</p> Signup and view all the answers

    A 44-year-old woman presents with headache, confusion, and seizures, along with bilateral posterior cerebral edema. What is the most likely diagnosis?

    <p>Reversible posterior leukoencephalopathy syndrome (RPLS)</p> Signup and view all the answers

    What is the initial treatment approach for a patient diagnosed with Reversible posterior leukoencephalopathy syndrome (RPLS)?

    <p>Gradual blood pressure reduction</p> Signup and view all the answers

    Which of the following symptoms is NOT typically associated with Reversible posterior leukoencephalopathy syndrome (RPLS)?

    <p>Rigidity</p> Signup and view all the answers

    What condition is characterized by spontaneous bleeding due to vascular malformations and was present in the 5-year-old boy?

    <p>Hereditary hemorrhagic telangiectasia (HHT)</p> Signup and view all the answers

    Which symptom was NOT reported in the case of the 5-year-old boy?

    <p>Seizures</p> Signup and view all the answers

    What was the likely imaging finding in the boy's head CT that indicated hemorrhagic stroke?

    <p>Hyperdense fluid collection</p> Signup and view all the answers

    What serious condition resulted from the ruptured arteriovenous malformation (AVM) in the child?

    <p>Hemorrhagic stroke</p> Signup and view all the answers

    What is the most appropriate diagnostic method for confirming arteriovenous malformation (AVM) in this case?

    <p>Angiography</p> Signup and view all the answers

    What is the most likely diagnosis for a 40-year-old woman with daily headaches, facial pain, and tenderness in the right masseter muscle?

    <p>Temporomandibular disorder (TMD)</p> Signup and view all the answers

    What specific symptom is indicative of location-related pain related to the condition presented?

    <p>Right-sided temporal/periorbital pain</p> Signup and view all the answers

    Which symptom, according to the scenario, is least likely to be involved in diagnosing a Temporomandibular disorder?

    <p>Nausea</p> Signup and view all the answers

    In evaluating the 40-year-old woman's condition, which aspect of her medical history contributes most to the diagnosis of TMD?

    <p>Presence of daily headaches</p> Signup and view all the answers

    Which physical symptom observed in the woman could be a direct sign of Temporomandibular disorder?

    <p>Tenderness in the right masseter muscle</p> Signup and view all the answers

    Study Notes

    Neuro Case Studies

    • 28-year-old woman: Abdominal pain, bilateral proximal upper extremity weakness, autonomic dysfunction, elevated urinary porphyrin levels. Acute Intermittent Porphyria (AIP) suspected. Urinary porphyrin level testing needed.

    • 65-year-old man: Tremor in left hand, stiffness, slow movements, asymmetric resting tremor, stepwise resistance to passive movement (rigidity), bradykinesia. Parkinson disease likely. No additional diagnostic testing needed.

    • 67-year-old man: Intermittent memory loss, misplacing objects, forgetting appointments, performs daily activities independently, family history of dementia. Mild cognitive impairment or dementia. Mini-Mental State Examination administered.

    • 45-year-old man: Excessive muscle wasting (distal, asymmetric), fasciculations, hyperreflexia, spasticity, dysarthria, dysphagia. Amyotrophic Lateral Sclerosis (ALS) suspected.

    • 7-year-old boy: Seizure, confusion, café-au-lait macules, axillary and inguinal freckling, family history. Neurofibromatosis Type 1 (NF1) possible. Optic pathway glioma in the context of NF1. Neurofibromas. Neurofibromatosis tests.

    • 5-year-old boy: Morning headache, visual changes, café-au-lait macules, and axillary freckles. Neurofibromatosis type 1 with optic pathway glioma suspected. Brain and orbital MRI needed.

    • 65-year-old man: Tingling, numbness, and burning pain in bilateral hands, worsens during hemodialysis. Dialysis-related amyloidosis and carpal tunnel syndrome are possible.

    • 76-year-old woman: New, right-sided headache, malaise, elevated ESR (55 mm/hr), suspected Giant Cell Arteritis (GCA). Temporal artery biopsy needed.

    • 74-year-old woman: Acute monocular vision loss in right eye. History of headaches, malaise, and fatigue, and lateral scalp tenderness. Giant cell arteritis (GCA) likely, requiring high-dose systemic glucocorticoids.

    • 38-year-old woman: Intermittent episodes of left foot weakness and numbness, diminished sensation over dorsum of left foot, foot drop, inability to walk on left heel. Common fibular (peroneal) neuropathy suspected. Peripheral nerve compression.

    • 35-year-old man: Motorcycle crash, bilateral lower extremity weakness, diminished bilateral pain and temperature sensation, intact proprioception, vibration, and light touch. Anterior cord syndrome suspected.

    • 69-year-old man: Bilateral lower extremity weakness, flaccid paralysis, intact vibratory sensation, urinary retention, recent thoracic aortic aneurysm repair. Spinal cord infarction is a possible diagnosis. Anterior cord syndrome.

    • 32-year-old man: Schizophrenia on risperidone, erectile dysfunction, decreased libido, bilateral breast enlargement (gynecomastia). Hyperprolactinemia due to decreased dopamine activity in the tuberoinfundibular pathway.

    Additional Case Studies (Page 2 onwards)

    • Include additional cases, summarizing data similarly to above. Each case is independently detailed focusing on facts, without repeating redundant elements.

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    Description

    Test your knowledge on the distinctions between early-onset postural instability and idiopathic Parkinson's disease, as well as symptoms associated with amyotrophic lateral sclerosis (ALS). This quiz covers various diagnostic techniques and patient presentations related to these neurological conditions, making it ideal for students and professionals in the field of neurology.

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