Podcast
Questions and Answers
Which type of immune response is activated by tuberculin and mycolic acid?
Which type of immune response is activated by tuberculin and mycolic acid?
- Cell-mediated immunity (correct)
- Autoimmune response
- Humoral immunity
- Innate immunity
What is the role of sulfatides in Mycobacterium tuberculosis?
What is the role of sulfatides in Mycobacterium tuberculosis?
- Promote exotoxin production
- Contribute to delayed hypersensitivity (correct)
- Inhibit phagosome-lysosome fusion
- Mediate granulomas and caseation
What is the classic example of delayed type IV hypersensitivity?
What is the classic example of delayed type IV hypersensitivity?
- Mantoux tuberculin test (correct)
- PCR test for tuberculosis
- Western blot test for tuberculosis
- ELISA test for tuberculosis
Which cytokines must be produced by macrophages to effectively control Mycobacterium tuberculosis?
Which cytokines must be produced by macrophages to effectively control Mycobacterium tuberculosis?
Which cells are at great risk of reactivating Mycobacterium tuberculosis if patients receive anti-TNFα monoclonal antibodies?
Which cells are at great risk of reactivating Mycobacterium tuberculosis if patients receive anti-TNFα monoclonal antibodies?
What is the main effect of hypoxic conditions on infiltrating macrophages in Mycobacterium tuberculosis infection?
What is the main effect of hypoxic conditions on infiltrating macrophages in Mycobacterium tuberculosis infection?
Which type of immune response involves activation of phagocytes, natural killer cells, and antigen-specific T-lymphocytes?
Which type of immune response involves activation of phagocytes, natural killer cells, and antigen-specific T-lymphocytes?
What is the most important characteristic of Mycobacterium tuberculosis that allows its intracellular survival?
What is the most important characteristic of Mycobacterium tuberculosis that allows its intracellular survival?
Which response correlates with the increased risk of Mycobacterium tuberculosis infection?
Which response correlates with the increased risk of Mycobacterium tuberculosis infection?
Which antibodies are not involved in the immune response against Mycobacterium tuberculosis?
Which antibodies are not involved in the immune response against Mycobacterium tuberculosis?
What is the primary function of autophagosomes?
What is the primary function of autophagosomes?
What is the outcome of fusion of Mtb-laden phagosome with an autophagosome?
What is the outcome of fusion of Mtb-laden phagosome with an autophagosome?
What happens if the environment inside the lysosomal fusion acidifies?
What happens if the environment inside the lysosomal fusion acidifies?
What is the role of virulent Mtb in the host cell?
What is the role of virulent Mtb in the host cell?
What is the consequence of cell death during Mtb infection?
What is the consequence of cell death during Mtb infection?
What can lead to mycobacterial replication and disease symptoms later in life?
What can lead to mycobacterial replication and disease symptoms later in life?
What is the potential outcome of reactivational TB?
What is the potential outcome of reactivational TB?
What are the symptoms associated with primary pulmonary TB?
What are the symptoms associated with primary pulmonary TB?
What occurs if organisms remain viable within the Ghon complex?
What occurs if organisms remain viable within the Ghon complex?
What is a potential consequence of erosion of granulomas into airways later in life?
What is a potential consequence of erosion of granulomas into airways later in life?
What is the classic example of delayed type IV hypersensitivity?
What is the classic example of delayed type IV hypersensitivity?
Which cells are at great risk of reactivating Mycobacterium tuberculosis if patients receive anti-TNFα monoclonal antibodies?
Which cells are at great risk of reactivating Mycobacterium tuberculosis if patients receive anti-TNFα monoclonal antibodies?
What occurs if organisms remain viable within the Ghon complex?
What occurs if organisms remain viable within the Ghon complex?
What is the role of sulfatides in Mycobacterium tuberculosis?
What is the role of sulfatides in Mycobacterium tuberculosis?
What is the main effect of hypoxic conditions on infiltrating macrophages in Mycobacterium tuberculosis infection?
What is the main effect of hypoxic conditions on infiltrating macrophages in Mycobacterium tuberculosis infection?
What is the potential outcome of reactivational TB?
What is the potential outcome of reactivational TB?
Which cytokines must be produced by macrophages to effectively control Mycobacterium tuberculosis?
Which cytokines must be produced by macrophages to effectively control Mycobacterium tuberculosis?
What is the primary function of autophagosomes?
What is the primary function of autophagosomes?
Which type of immune response involves activation of phagocytes, natural killer cells, and antigen-specific T-lymphocytes?
Which type of immune response involves activation of phagocytes, natural killer cells, and antigen-specific T-lymphocytes?
What is the consequence of cell death during Mtb infection?
What is the consequence of cell death during Mtb infection?
What is the primary function of autophagosomes?
What is the primary function of autophagosomes?
What occurs if organisms remain viable within the Ghon complex?
What occurs if organisms remain viable within the Ghon complex?
What is the main effect of hypoxic conditions on infiltrating macrophages in Mycobacterium tuberculosis infection?
What is the main effect of hypoxic conditions on infiltrating macrophages in Mycobacterium tuberculosis infection?
Which type of immune response is activated by tuberculin and mycolic acid?
Which type of immune response is activated by tuberculin and mycolic acid?
What is the role of sulfatides in Mycobacterium tuberculosis?
What is the role of sulfatides in Mycobacterium tuberculosis?
What happens if the environment inside the lysosomal fusion acidifies?
What happens if the environment inside the lysosomal fusion acidifies?
What is a potential consequence of erosion of granulomas into airways later in life?
What is a potential consequence of erosion of granulomas into airways later in life?
What is the consequence of cell death during Mtb infection?
What is the consequence of cell death during Mtb infection?
What is the most important characteristic of Mycobacterium tuberculosis that allows its intracellular survival?
What is the most important characteristic of Mycobacterium tuberculosis that allows its intracellular survival?
Which cytokines must be produced by macrophages to effectively control Mycobacterium tuberculosis?
Which cytokines must be produced by macrophages to effectively control Mycobacterium tuberculosis?
