Myasthenia Gravis Classification and Genetic Factors
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Questions and Answers

Which muscle group is most commonly affected in myasthenia gravis?

  • Abdominal muscles
  • Facial muscles (correct)
  • Leg muscles
  • Back muscles
  • What is the first noticeable sign in most cases of myasthenia gravis?

  • Double vision
  • Difficulty swallowing
  • Weakness in the arms (correct)
  • Slurred speech
  • Which activity is most likely to worsen myasthenia gravis?

  • Meditation
  • Cooking
  • Sunbathing (correct)
  • Reading
  • Which medication can exacerbate myasthenia gravis symptoms?

    <p>Calcium channel blockers</p> Signup and view all the answers

    What contributes to the production of autoantibodies in SLE?

    <p>Hormonal changes</p> Signup and view all the answers

    What type of gait is often seen in patients with myasthenia gravis?

    <p>Waddling gait</p> Signup and view all the answers

    Which symptom of SLE is associated with peripheral nerve damage?

    <p>Facial pain</p> Signup and view all the answers

    Which of the following is a symptom that can present in both myasthenia gravis and other conditions?

    <p>Difficulty swallowing</p> Signup and view all the answers

    What may lead to a more regionalized mononeuritis multiplex in SLE patients over time?

    <p>Chronic inflammatory diseases</p> Signup and view all the answers

    Which treatment for SLE can cause papilledema or pseudotumor?

    <p>Corticosteroids</p> Signup and view all the answers

    What symptom of SLE can be attributed to pericarditis or pleurisy?

    <p>Chest Pain</p> Signup and view all the answers

    In which group has SLE been found to have a higher prevalence according to the text?

    <p>Women during reproductive years</p> Signup and view all the answers

    Which test is commonly used to detect antibodies against the body's own cells in SLE?

    <p>Antinuclear Antibodies Test (ANA)</p> Signup and view all the answers

    Which antibodies are more specific for SLE and not typically found in other autoimmune diseases?

    <p>Anti-dsDNA and Anti-Sm (Smith) Antibodies</p> Signup and view all the answers

    What is detected through urinalysis to indicate kidney involvement in SLE?

    <p>Proteinuria</p> Signup and view all the answers

    Which complication of SLE involves inflammation of the eyes and ocular manifestations?

    <p>Eye Complications</p> Signup and view all the answers

    What do ESR and CRP test results indicate in SLE patients?

    <p>Inflammation</p> Signup and view all the answers

    In SLE, which complication is associated with seizures, cognitive dysfunction, and neuropsychiatric symptoms?

    <p>Neurological Complications</p> Signup and view all the answers

    Which genetic factors may increase the risk of developing Myasthenia Gravis?

    <p>Genes associated with the production of autoantibodies or immune system regulation</p> Signup and view all the answers

    In the classification system for Myasthenia Gravis, what does Class V indicate?

    <p>Severe muscle weakness requiring intubation or mechanical ventilation</p> Signup and view all the answers

    What happens at neuromuscular junctions in the pathophysiology of Myasthenia Gravis?

    <p>Anti-acetylcholine receptor antibodies target receptors on certain muscle cells</p> Signup and view all the answers

    What is the result of the autoimmune response in Myasthenia Gravis patients with anti-AChR antibodies?

    <p>Decreased number of Ach causing nerve transmission failures and muscle weakness</p> Signup and view all the answers

    Which additional protein can be targeted by antibodies in some Myasthenia Gravis patients?

    <p>Muscle specific kinase protein (MuSK)</p> Signup and view all the answers

    What does Plasmapheresis involve in the treatment of Myasthenia Gravis?

    <p>Filtering blood to remove harmful antibodies or other factors</p> Signup and view all the answers

    Which ocular manifestation of Systemic Lupus Erythematosus (SLE) involves symptoms like keratoconjunctivitis sicca, punctate epithelial loss, and peripheral ulcerative keratitis?

    <p>Keratoconjunctivitis sicca</p> Signup and view all the answers

    What ocular manifestation of SLE involves cotton wool spots, hard exudates, and retinal hemorrhages?

    <p>Choroid</p> Signup and view all the answers

    Which test is used to measure tear production and evaluate dry eye symptoms in patients with SLE?

    <p>Schirmer's Test</p> Signup and view all the answers

    In SLE, which blood test is commonly used to help confirm the diagnosis?

    <p>Antinuclear antibodies (ANA)</p> Signup and view all the answers

    Which ocular manifestation of SLE involves symptoms like optic neuritis, optic neuropathy, and diplopia?

    <p>Optic neuritis</p> Signup and view all the answers

    What imaging test is used to study blood flow in the retina, particularly useful for detecting retinopathy in patients with SLE?

    <p>Fluorescein Angiography</p> Signup and view all the answers

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