Myasthenia Gravis Classification and Genetic Factors
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Questions and Answers

Which muscle group is most commonly affected in myasthenia gravis?

  • Abdominal muscles
  • Facial muscles (correct)
  • Leg muscles
  • Back muscles

What is the first noticeable sign in most cases of myasthenia gravis?

  • Double vision
  • Difficulty swallowing
  • Weakness in the arms (correct)
  • Slurred speech

Which activity is most likely to worsen myasthenia gravis?

  • Meditation
  • Cooking
  • Sunbathing (correct)
  • Reading

Which medication can exacerbate myasthenia gravis symptoms?

<p>Calcium channel blockers (C)</p> Signup and view all the answers

What contributes to the production of autoantibodies in SLE?

<p>Hormonal changes (A)</p> Signup and view all the answers

What type of gait is often seen in patients with myasthenia gravis?

<p>Waddling gait (C)</p> Signup and view all the answers

Which symptom of SLE is associated with peripheral nerve damage?

<p>Facial pain (B)</p> Signup and view all the answers

Which of the following is a symptom that can present in both myasthenia gravis and other conditions?

<p>Difficulty swallowing (D)</p> Signup and view all the answers

What may lead to a more regionalized mononeuritis multiplex in SLE patients over time?

<p>Chronic inflammatory diseases (B)</p> Signup and view all the answers

Which treatment for SLE can cause papilledema or pseudotumor?

<p>Corticosteroids (B)</p> Signup and view all the answers

What symptom of SLE can be attributed to pericarditis or pleurisy?

<p>Chest Pain (B)</p> Signup and view all the answers

In which group has SLE been found to have a higher prevalence according to the text?

<p>Women during reproductive years (B)</p> Signup and view all the answers

Which test is commonly used to detect antibodies against the body's own cells in SLE?

<p>Antinuclear Antibodies Test (ANA) (D)</p> Signup and view all the answers

Which antibodies are more specific for SLE and not typically found in other autoimmune diseases?

<p>Anti-dsDNA and Anti-Sm (Smith) Antibodies (B)</p> Signup and view all the answers

What is detected through urinalysis to indicate kidney involvement in SLE?

<p>Proteinuria (C)</p> Signup and view all the answers

Which complication of SLE involves inflammation of the eyes and ocular manifestations?

<p>Eye Complications (A)</p> Signup and view all the answers

What do ESR and CRP test results indicate in SLE patients?

<p>Inflammation (A)</p> Signup and view all the answers

In SLE, which complication is associated with seizures, cognitive dysfunction, and neuropsychiatric symptoms?

<p>Neurological Complications (B)</p> Signup and view all the answers

Which genetic factors may increase the risk of developing Myasthenia Gravis?

<p>Genes associated with the production of autoantibodies or immune system regulation (C)</p> Signup and view all the answers

In the classification system for Myasthenia Gravis, what does Class V indicate?

<p>Severe muscle weakness requiring intubation or mechanical ventilation (B)</p> Signup and view all the answers

What happens at neuromuscular junctions in the pathophysiology of Myasthenia Gravis?

<p>Anti-acetylcholine receptor antibodies target receptors on certain muscle cells (D)</p> Signup and view all the answers

What is the result of the autoimmune response in Myasthenia Gravis patients with anti-AChR antibodies?

<p>Decreased number of Ach causing nerve transmission failures and muscle weakness (D)</p> Signup and view all the answers

Which additional protein can be targeted by antibodies in some Myasthenia Gravis patients?

<p>Muscle specific kinase protein (MuSK) (D)</p> Signup and view all the answers

What does Plasmapheresis involve in the treatment of Myasthenia Gravis?

<p>Filtering blood to remove harmful antibodies or other factors (A)</p> Signup and view all the answers

Which ocular manifestation of Systemic Lupus Erythematosus (SLE) involves symptoms like keratoconjunctivitis sicca, punctate epithelial loss, and peripheral ulcerative keratitis?

<p>Keratoconjunctivitis sicca (B)</p> Signup and view all the answers

What ocular manifestation of SLE involves cotton wool spots, hard exudates, and retinal hemorrhages?

<p>Choroid (A)</p> Signup and view all the answers

Which test is used to measure tear production and evaluate dry eye symptoms in patients with SLE?

<p>Schirmer's Test (B)</p> Signup and view all the answers

In SLE, which blood test is commonly used to help confirm the diagnosis?

<p>Antinuclear antibodies (ANA) (D)</p> Signup and view all the answers

Which ocular manifestation of SLE involves symptoms like optic neuritis, optic neuropathy, and diplopia?

<p>Optic neuritis (D)</p> Signup and view all the answers

What imaging test is used to study blood flow in the retina, particularly useful for detecting retinopathy in patients with SLE?

<p>Fluorescein Angiography (D)</p> Signup and view all the answers

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