Myasthenia Gravis Classification and Genetic Factors

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Which muscle group is most commonly affected in myasthenia gravis?

Abdominal muscles

Facial muscles (correct)

Leg muscles

Back muscles

What is the first noticeable sign in most cases of myasthenia gravis?

Double vision

Difficulty swallowing

Weakness in the arms (correct)

Slurred speech

Which activity is most likely to worsen myasthenia gravis?

Meditation

Cooking

Sunbathing (correct)

Reading

Which medication can exacerbate myasthenia gravis symptoms?

Calcium channel blockers Signup and view all the answers

What contributes to the production of autoantibodies in SLE?

Hormonal changes Signup and view all the answers

What type of gait is often seen in patients with myasthenia gravis?

Waddling gait Signup and view all the answers

Which symptom of SLE is associated with peripheral nerve damage?

Facial pain Signup and view all the answers

Which of the following is a symptom that can present in both myasthenia gravis and other conditions?

Difficulty swallowing Signup and view all the answers

What may lead to a more regionalized mononeuritis multiplex in SLE patients over time?

Chronic inflammatory diseases Signup and view all the answers

Which treatment for SLE can cause papilledema or pseudotumor?

Corticosteroids Signup and view all the answers

What symptom of SLE can be attributed to pericarditis or pleurisy?

Chest Pain Signup and view all the answers

In which group has SLE been found to have a higher prevalence according to the text?

Women during reproductive years Signup and view all the answers

Which test is commonly used to detect antibodies against the body's own cells in SLE?

Antinuclear Antibodies Test (ANA) Signup and view all the answers

Which antibodies are more specific for SLE and not typically found in other autoimmune diseases?

Anti-dsDNA and Anti-Sm (Smith) Antibodies Signup and view all the answers

What is detected through urinalysis to indicate kidney involvement in SLE?

Proteinuria Signup and view all the answers

Which complication of SLE involves inflammation of the eyes and ocular manifestations?

Eye Complications Signup and view all the answers

What do ESR and CRP test results indicate in SLE patients?

Inflammation Signup and view all the answers

In SLE, which complication is associated with seizures, cognitive dysfunction, and neuropsychiatric symptoms?

Neurological Complications Signup and view all the answers

Which genetic factors may increase the risk of developing Myasthenia Gravis?

Genes associated with the production of autoantibodies or immune system regulation Signup and view all the answers

In the classification system for Myasthenia Gravis, what does Class V indicate?

Severe muscle weakness requiring intubation or mechanical ventilation Signup and view all the answers

What happens at neuromuscular junctions in the pathophysiology of Myasthenia Gravis?

Anti-acetylcholine receptor antibodies target receptors on certain muscle cells Signup and view all the answers

What is the result of the autoimmune response in Myasthenia Gravis patients with anti-AChR antibodies?

Decreased number of Ach causing nerve transmission failures and muscle weakness Signup and view all the answers

Which additional protein can be targeted by antibodies in some Myasthenia Gravis patients?

Muscle specific kinase protein (MuSK) Signup and view all the answers

What does Plasmapheresis involve in the treatment of Myasthenia Gravis?

Filtering blood to remove harmful antibodies or other factors Signup and view all the answers

Which ocular manifestation of Systemic Lupus Erythematosus (SLE) involves symptoms like keratoconjunctivitis sicca, punctate epithelial loss, and peripheral ulcerative keratitis?

Keratoconjunctivitis sicca Signup and view all the answers

What ocular manifestation of SLE involves cotton wool spots, hard exudates, and retinal hemorrhages?

Choroid Signup and view all the answers

Which test is used to measure tear production and evaluate dry eye symptoms in patients with SLE?

Schirmer's Test Signup and view all the answers

In SLE, which blood test is commonly used to help confirm the diagnosis?

Antinuclear antibodies (ANA) Signup and view all the answers

Which ocular manifestation of SLE involves symptoms like optic neuritis, optic neuropathy, and diplopia?

Optic neuritis Signup and view all the answers

What imaging test is used to study blood flow in the retina, particularly useful for detecting retinopathy in patients with SLE?

Fluorescein Angiography Signup and view all the answers