Montelukast and Mast Cell Stabilizers Quiz
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Questions and Answers

What is the function of the respiratory system?

  • Perform gas exchange between the body and its environment (correct)
  • Deliver carbon dioxide to the tissues
  • Regulate body temperature
  • Assist in digestion

What does anoxia refer to?

  • Deficiency of hemoglobin
  • Reduced supply of oxygen
  • Retention of carbon dioxide in the body
  • Complete failure of the tissue to receive adequate oxygen supply (correct)

Which type of anoxia is typically caused by a primary disease of the respiratory tract?

  • Anemic anoxia
  • Histotoxic anoxia
  • Anoxic anoxia (correct)
  • Stagnant anoxia

What is hypercapnia?

<p>Retention of carbon dioxide in the body (D)</p> Signup and view all the answers

What compensatory mechanism can be triggered by slow development of anoxia?

<p>Increase in depth and rate of respiratory movement (hyperpnea) (A)</p> Signup and view all the answers

What role do chemoreceptors of the carotid and aortic bodies play in compensatory mechanisms during anoxia?

<p>Regulate respiratory movements (D)</p> Signup and view all the answers

What is the mechanism of action for Cromolyn Sodium?

<p>Inhibiting calcium channels in mast cells (C)</p> Signup and view all the answers

Which drug is considered a mast cell stabilizer?

<p>Nedocromil (A)</p> Signup and view all the answers

How do Methylxanthines like Theophylline work to relieve bronchospasm?

<p>By inhibiting phosphodiesterase (C)</p> Signup and view all the answers

Which disorder is NOT listed as a condition for long-term control with Theophylline?

<p>Allergic rhinitis (D)</p> Signup and view all the answers

What class of drugs are used to prevent asthma attacks?

<p>Mast cell stabilizers (B)</p> Signup and view all the answers

Why is Aminophylline preferred when an I.V. methylxanthine is required?

<p>To prevent inflammatory mediator release (C)</p> Signup and view all the answers

Which type of antitussives are absorbed well through the GI tract, metabolized in the liver, and excreted in urine?

<p>Codeine (A)</p> Signup and view all the answers

What is the objective of antitussive therapy?

<p>To suppress cough without impairing evacuation of broncho-pulmonary secretions (C)</p> Signup and view all the answers

Which type of antitussives are typically used to treat dry, nonproductive coughs?

<p>Dextromethorphan (D)</p> Signup and view all the answers

How do CNS depressant antitussives work?

<p>By depressing the cough center in the medulla oblongata (C)</p> Signup and view all the answers

Which opiates are potent antitussive agents according to the text?

<p>Morphine (D)</p> Signup and view all the answers

What is a common method by which coughing can be suppressed?

<p>By soothing irritated respiratory mucous membrane (D)</p> Signup and view all the answers

How do corticosteroids work in the body?

<p>By inhibiting the production of cytokines, leukotrienes, and prostaglandins (A)</p> Signup and view all the answers

What is a common route of administration for corticosteroids in acute asthma attacks?

<p>Intravenous (IV) administration (D)</p> Signup and view all the answers

Which of the following is NOT an example of an inhaled corticosteroid mentioned in the text?

<p>Hydrocortisone sodium succinate (C)</p> Signup and view all the answers

What is the primary function of corticosteroids in the treatment of asthma?

<p>To reduce inflammation and swelling in the respiratory tract (B)</p> Signup and view all the answers

Which form of corticosteroids has a rapid onset of action?

<p>Intravenous (IV) corticosteroids (A)</p> Signup and view all the answers

What is one possible adverse effect of corticosteroids due to their effect on other areas in the body?

<p>Long-term adverse reactions (C)</p> Signup and view all the answers

Which category of drugs directly act on the respiratory lining cells to increase secretory activity?

<p>Expectorants (C)</p> Signup and view all the answers

What is the mode of action of indirectly acting expectorants?

<p>Irritate nerve endings in the stomach mucosa (B)</p> Signup and view all the answers

Which drug category includes medications like Phenylephrine and Oxymetazoline that constrict blood vessels in mucus membranes?

<p>Antihistamines (B)</p> Signup and view all the answers

What is the mode of action of antitussives that are centrally acting?

<p>Depress cough center in the medulla oblongata (B)</p> Signup and view all the answers

Which drug category is used to counteract bronchoconstriction caused by histamine during allergic reactions?

<p>Bronchodilators (B)</p> Signup and view all the answers

What do bronchodilators like Clenbuterol and Salbutamol do?

<p>Counteract bronchoconstriction caused by histamine (A)</p> Signup and view all the answers

Study Notes

Respiratory System

  • The function of the respiratory system is not explicitly stated in the text.

Anoxia

  • Anoxia refers to a state of oxygen deficiency.
  • Intrapulmonary anoxia is typically caused by a primary disease of the respiratory tract.

Hypercapnia

  • Hypercapnia is not explicitly defined in the text, but it refers to a state of elevated carbon dioxide in the blood.

Compensatory Mechanisms

  • In cases of slow development of anoxia, a compensatory mechanism can be triggered, although the specific mechanism is not stated.

Chemoreceptors

  • Chemoreceptors in the carotid and aortic bodies play a role in compensatory mechanisms during anoxia.

Cromolyn Sodium

  • Cromolyn Sodium is a drug that prevents the release of inflammatory chemicals from mast cells.
  • It is considered a mast cell stabilizer.

Methylxanthines

  • Methylxanthines, such as Theophylline, relieve bronchospasm by increasing the concentration of cAMP, which relaxes smooth muscle.

Theophylline

  • Theophylline is used for long-term control of conditions such as asthma, but not for ARDS (Acute Respiratory Distress Syndrome).
  • Aminophylline is preferred when an IV methylxanthine is required.

Antitussives

  • Antitussives are used to relieve coughs.
  • The objective of antitussive therapy is to suppress coughing.
  • Opiates are potent antitussive agents.
  • CNS depressant antitussives work by reducing the sensitivity of the cough center in the brain.
  • Expectorants increase secretory activity in the respiratory tract.
  • Mucolytics break down mucus.

Corticosteroids

  • Corticosteroids work by suppressing the immune response and reducing inflammation.
  • They are often administered through inhalation for acute asthma attacks.
  • The primary function of corticosteroids in the treatment of asthma is to reduce inflammation.
  • Corticosteroids can have a rapid onset of action in their IV form.
  • A possible adverse effect of corticosteroids is suppression of the hypothalamic-pituitary-adrenal axis.

Bronchodilators

  • Bronchodilators, such as Clenbuterol and Salbutamol, relax smooth muscle in the airways, relieving bronchoconstriction.

Expectorants

  • Expectorants increase secretory activity in the respiratory tract.
  • Indirectly acting expectorants work by stimulating the vagus nerve.

Decongestants

  • Decongestants, such as Phenylephrine and Oxymetazoline, constrict blood vessels in mucus membranes, reducing swelling.

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Test your knowledge on Montelukast and Mast Cell Stabilizers, their indications, and mechanisms of action. Understand the role of these drugs in managing allergic rhinitis and preventing asthma attacks.

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