Montelukast (Singulair) Flashcards

Study Notes

Singulair (Montelukast) Overview

Singulair is the trade name for montelukast, a medication used primarily for respiratory conditions.
Montelukast is the generic name indicating its active ingredient.

Classification

Classified as a leukotriene modifier, it is an anti-inflammatory medication beneficial for asthma prophylaxis.

Mechanism of Action

Works by preventing airway edema and reducing inflammation through the blockage of leukotriene receptors within the airways.

Indications for Use

Prescribed for the prophylaxis of persistent and chronic asthma, exercise-induced bronchospasm, and allergic rhinitis.

Administration Details

Administered orally (PO) and works rapidly, but is not suitable for the termination of acute bronchospasm.
Approved for pediatric use, available as chewable tablets and granules, which can be mixed with soft foods like applesauce or ice cream.

Common Side Effects

Possible side effects include headache, cough, nasal congestion, and gastrointestinal upset.

Notable Adverse Effects

Generally produces few serious adverse effects; most commonly reported is headache.
Some patients may experience nausea and diarrhea.
Rare but serious effects include suicidal ideation, hallucinations, aggressiveness, or depression.

Laboratory Considerations

May cause an increase in serum alanine aminotransferase (ALT) values, warranting monitoring.

Nursing Considerations

Administer in the evening for optimal effect; full benefits may take up to one week to become evident.
Peak effectiveness occurs within 3-4 hours post-administration.
Monitor the "big three": respiratory rate (RR), heart rate (HR), and lung function.

Patient Education

Advise patients to increase fluid intake and report any signs of shortness of breath (SOB) or behavioral changes.
Emphasize the importance of taking the medication as prescribed.

Contraindications

Not recommended for patients with significant hepatic dysfunction or chronic alcohol use due to extensive liver metabolism of the drug.

Description

Test your knowledge about Montelukast, commonly known as Singulair, through this flashcard quiz. Dive into its trade name, generic name, classification, mechanism of action, and uses in asthma prophylaxis. Perfect for students and professionals in pharmacy and healthcare fields.