Monoclonal and Polyclonal Antibodies
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Questions and Answers

What is the main consideration when choosing an animal for polyclonal antibody production?

  • Size of the animal
  • Foreignness of the antigen to the animal (correct)
  • Cost of the animal
  • Diet of the animal
  • Which of the following is a consideration when selecting an animal for antibody production?

  • Dietary requirements of the animal
  • Genetic similarity to humans
  • Color of the animal's fur
  • Genomic differences between animals of the same species (correct)
  • What type of animal is typically used for monoclonal antibody production?

  • Mouse (correct)
  • Rabbit
  • Sheep
  • Goat
  • Why is it important to consider convenience when choosing an animal for antibody production?

    <p>To ensure the animal is easy to buy and maintain</p> Signup and view all the answers

    What is the typical size of animals used for polyclonal antibody production?

    <p>Large</p> Signup and view all the answers

    What is the significance of using an animal with a different genome for polyclonal antibody production?

    <p>To increase the chances of producing antibodies</p> Signup and view all the answers

    Why is it important to consider foreignness when selecting an animal for antibody production?

    <p>To ensure the antigen is recognized by the animal's immune system</p> Signup and view all the answers

    What is the main difference between monoclonal and polyclonal antibody production in terms of the animal used?

    <p>The type of animal used</p> Signup and view all the answers

    Why is it important to use the same strain of animal for polyclonal antibody production?

    <p>To minimize genetic variations</p> Signup and view all the answers

    What is the benefit of using a large animal for polyclonal antibody production?

    <p>It produces a higher yield of antibodies</p> Signup and view all the answers

    Study Notes

    Monoclonal and Polyclonal Antibodies

    • Monoclonal antibodies are typically produced in mice.
    • Polyclonal antibodies are typically produced in larger animals, such as rabbits, goats, or sheep.

    Choosing the Right Animal for Antibody Production

    • The antigen should be foreign to the animal to ensure an effective immune response.
    • Consider convenience factors, such as ease of purchase, care, and space requirements.
    • Choose an animal with a consistent genome, as even animals of the same species can have slightly different genomes; use the same strain of animal for optimal results.

    Monoclonal and Polyclonal Antibodies

    • Monoclonal antibodies are typically produced in mice.
    • Polyclonal antibodies are typically produced in larger animals, such as rabbits, goats, or sheep.

    Choosing the Right Animal for Antibody Production

    • The antigen should be foreign to the animal to ensure an effective immune response.
    • Consider convenience factors, such as ease of purchase, care, and space requirements.
    • Choose an animal with a consistent genome, as even animals of the same species can have slightly different genomes; use the same strain of animal for optimal results.

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    Description

    Learn about the differences between monoclonal and polyclonal antibodies, and the factors to consider when choosing an animal for antibody production.

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