10 Questions
What is the primary consideration for selecting the animal for inducing antibody production?
Foreignness of the antigen to the animal
Which type of antibody production typically involves a large animal?
Polyclonal
What is a key factor to consider when working with animals of the same species?
Genetic differences
What is the typical animal used for monoclonal antibody production?
Mouse
Why is it important to use the same strain of animal?
To minimize genetic variations
What is the main reason why the antigen should be foreign to the animal?
To prevent the animal from recognizing the antigen as its own
Why is it important to consider the genome of the animal?
Because it varies between animals of the same species
What is the main advantage of using the same strain of animal?
It ensures consistency in the antibody production process
What is a consideration when choosing an animal for antibody production, aside from foreignness and genome?
Convenience of buying and caring for the animal
Which type of antibody production is usually associated with rabbits, goats, or sheep?
Polyclonal antibody production
Study Notes
Antibody Production in Animals
- To induce antibody production, mice are suitable for monoclonal antibodies
- For polyclonal antibodies, larger animals such as rabbits, goats, or sheep are preferred
- When choosing an animal, consider the following factors:
- Foreignness: The antigen should be foreign to the animal to ensure an immune response
- Convenience: Choose an animal that is easy to care for, purchase, and maintain, with minimal space requirements
- Genome: Even animals of the same species have slightly different genomes, so it's best to use the same strain of animal to minimize genetic variations
Antibody Production in Animals
- To induce antibody production, mice are suitable for monoclonal antibodies
- For polyclonal antibodies, larger animals such as rabbits, goats, or sheep are preferred
- When choosing an animal, consider the following factors:
- Foreignness: The antigen should be foreign to the animal to ensure an immune response
- Convenience: Choose an animal that is easy to care for, purchase, and maintain, with minimal space requirements
- Genome: Even animals of the same species have slightly different genomes, so it's best to use the same strain of animal to minimize genetic variations
Learn how antibody production in animals is induced and the factors to consider when choosing an animal for this process. Discover the importance of foreignness, convenience, and genome when selecting an animal for antibody production.
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