Antibody Production in Animals
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Questions and Answers

What is the primary consideration for selecting the animal for inducing antibody production?

  • Convenience of animal care
  • Foreignness of the antigen to the animal (correct)
  • Genetic similarity to humans
  • Cost of animal feed
  • Which type of antibody production typically involves a large animal?

  • Chimeric
  • Polyclonal (correct)
  • Monoclonal
  • Recombinant
  • What is a key factor to consider when working with animals of the same species?

  • Environmental factors
  • Diet and nutrition
  • Genetic differences (correct)
  • Age and sex
  • What is the typical animal used for monoclonal antibody production?

    <p>Mouse</p> Signup and view all the answers

    Why is it important to use the same strain of animal?

    <p>To minimize genetic variations</p> Signup and view all the answers

    What is the main reason why the antigen should be foreign to the animal?

    <p>To prevent the animal from recognizing the antigen as its own</p> Signup and view all the answers

    Why is it important to consider the genome of the animal?

    <p>Because it varies between animals of the same species</p> Signup and view all the answers

    What is the main advantage of using the same strain of animal?

    <p>It ensures consistency in the antibody production process</p> Signup and view all the answers

    What is a consideration when choosing an animal for antibody production, aside from foreignness and genome?

    <p>Convenience of buying and caring for the animal</p> Signup and view all the answers

    Which type of antibody production is usually associated with rabbits, goats, or sheep?

    <p>Polyclonal antibody production</p> Signup and view all the answers

    Study Notes

    Antibody Production in Animals

    • To induce antibody production, mice are suitable for monoclonal antibodies
    • For polyclonal antibodies, larger animals such as rabbits, goats, or sheep are preferred
    • When choosing an animal, consider the following factors:
      • Foreignness: The antigen should be foreign to the animal to ensure an immune response
      • Convenience: Choose an animal that is easy to care for, purchase, and maintain, with minimal space requirements
      • Genome: Even animals of the same species have slightly different genomes, so it's best to use the same strain of animal to minimize genetic variations

    Antibody Production in Animals

    • To induce antibody production, mice are suitable for monoclonal antibodies
    • For polyclonal antibodies, larger animals such as rabbits, goats, or sheep are preferred
    • When choosing an animal, consider the following factors:
      • Foreignness: The antigen should be foreign to the animal to ensure an immune response
      • Convenience: Choose an animal that is easy to care for, purchase, and maintain, with minimal space requirements
      • Genome: Even animals of the same species have slightly different genomes, so it's best to use the same strain of animal to minimize genetic variations

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    Description

    Learn how antibody production in animals is induced and the factors to consider when choosing an animal for this process. Discover the importance of foreignness, convenience, and genome when selecting an animal for antibody production.

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