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Questions and Answers
What is the primary function of Cohesin in the context of gene regulation?
What is the primary function of Cohesin in the context of gene regulation?
- To facilitate sister chromatid separation during mitosis
- To mediate chromatin looping at multiple gene loci (correct)
- To regulate DNA replication during S-phase
- To catalyze histone modification reactions
What is the term for self-interacting genomic regions that physically interact with each other more frequently than with sequences outside the region?
What is the term for self-interacting genomic regions that physically interact with each other more frequently than with sequences outside the region?
- Histone modification domains
- Topological associating domains (TADs) (correct)
- Nucleosome organization territories
- Chromosomal loops
How many histone proteins are typically found in a histone octamer?
How many histone proteins are typically found in a histone octamer?
- 8 (correct)
- 4
- 10
- 6
What is the name of the technique used to assess chromosomal looping and topologically associated domains?
What is the name of the technique used to assess chromosomal looping and topologically associated domains?
What is the typical length of DNA wrapped around a histone octamer in a nucleosome?
What is the typical length of DNA wrapped around a histone octamer in a nucleosome?
What is the primary function of CTCF in the context of chromatin organization?
What is the primary function of CTCF in the context of chromatin organization?
What is the primary function of euchromatin?
What is the primary function of euchromatin?
What is the term for the complex folded surfaces of chromosomal territories?
What is the term for the complex folded surfaces of chromosomal territories?
What is the purpose of regulatory sequences in eukaryotic gene structure?
What is the purpose of regulatory sequences in eukaryotic gene structure?
What is the term for the highly compacted, repressive gene state?
What is the term for the highly compacted, repressive gene state?
What is the term for the 3D organization of chromatin in the nucleus?
What is the term for the 3D organization of chromatin in the nucleus?
What is the term for the breaking and rejoining of chromatin fibers?
What is the term for the breaking and rejoining of chromatin fibers?
What is the primary function of Histone 1 (H1)?
What is the primary function of Histone 1 (H1)?
Which of the following families of chromatin remodeling enzymes is involved in spatially and temporally regulating gene expression?
Which of the following families of chromatin remodeling enzymes is involved in spatially and temporally regulating gene expression?
What is the characteristic of the 5’ and 3’ ends of genes?
What is the characteristic of the 5’ and 3’ ends of genes?
What is the result of mutations in almost all 9 CHD proteins?
What is the result of mutations in almost all 9 CHD proteins?
What is the characteristic of chromatin remodeling enzymes?
What is the characteristic of chromatin remodeling enzymes?
What is the function of chromatin remodeling enzymes in transcription regulation?
What is the function of chromatin remodeling enzymes in transcription regulation?
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