10 Questions
Which part of the nervous system surrounds the brain and spinal cord, providing support and protection?
Meninges
How do microbes typically enter the central nervous system?
Breaks in the bones and meninges
Which part of the nervous system has no normal microbiota?
Central nervous system
What is the main function of the meninges?
Provide support and protection
How can microbes penetrate the blood-brain barrier to infect the central nervous system?
By infecting and killing cells of the meninges
Which of the following is NOT a portal of infection for the Central Nervous System?
Direct colonization by normal microbiota
What is the main function of the meninges?
To protect the brain and spinal cord from external shock
How do microbes typically enter the central nervous system?
Through the circulation of cerebrospinal fluid
Which part of the nervous system has no normal microbiota?
The central nervous system
In what way can microbes penetrate the blood-brain barrier to infect the central nervous system?
By infecting and killing cells of the meninges
Study Notes
Central Nervous System (CNS)
- The meninges surround the brain and spinal cord, providing support and protection.
Infection of CNS
- Microbes typically enter the central nervous system through the bloodstream, direct trauma, or by contiguous spread from adjacent infected tissues.
- The CNS has no normal microbiota.
Meninges
- The main function of the meninges is to provide support and protection to the CNS.
Blood-Brain Barrier
- Microbes can penetrate the blood-brain barrier to infect the CNS by:
- Crossing the blood-brain barrier through the fenestrated endothelium of the blood vessels
- Using Trojan horse mechanisms, such as infected macrophages or leukocytes
- Exploiting the compromised integrity of the blood-brain barrier due to inflammation or trauma
Portals of Infection
- The following are portals of infection for the CNS: bloodstream, direct trauma, and contiguous spread from adjacent infected tissues.
- The eye is NOT a portal of infection for the CNS.
Test your knowledge of microbial diseases affecting the nervous system with this medical microbiology quiz. Covering the structure of the nervous system, including the brain, spinal cord, and peripheral nerves, this quiz delves into the impact of microbes on the meninges and nervous system function.
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