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Questions and Answers
Which part of the nervous system surrounds the brain and spinal cord, providing support and protection?
Which part of the nervous system surrounds the brain and spinal cord, providing support and protection?
- Axonal transport
- Peripheral nervous system
- Meninges (correct)
- Central nervous system
How do microbes typically enter the central nervous system?
How do microbes typically enter the central nervous system?
- Circulation of cerebrospinal fluid
- Medical procedures such as spinal taps
- Breaks in the bones and meninges (correct)
- Traveling via axonal transport
Which part of the nervous system has no normal microbiota?
Which part of the nervous system has no normal microbiota?
- Peripheral nervous system
- Central nervous system (correct)
- Axonal transport
- Meninges
What is the main function of the meninges?
What is the main function of the meninges?
How can microbes penetrate the blood-brain barrier to infect the central nervous system?
How can microbes penetrate the blood-brain barrier to infect the central nervous system?
Which of the following is NOT a portal of infection for the Central Nervous System?
Which of the following is NOT a portal of infection for the Central Nervous System?
What is the main function of the meninges?
What is the main function of the meninges?
How do microbes typically enter the central nervous system?
How do microbes typically enter the central nervous system?
Which part of the nervous system has no normal microbiota?
Which part of the nervous system has no normal microbiota?
In what way can microbes penetrate the blood-brain barrier to infect the central nervous system?
In what way can microbes penetrate the blood-brain barrier to infect the central nervous system?
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Study Notes
Central Nervous System (CNS)
- The meninges surround the brain and spinal cord, providing support and protection.
Infection of CNS
- Microbes typically enter the central nervous system through the bloodstream, direct trauma, or by contiguous spread from adjacent infected tissues.
- The CNS has no normal microbiota.
Meninges
- The main function of the meninges is to provide support and protection to the CNS.
Blood-Brain Barrier
- Microbes can penetrate the blood-brain barrier to infect the CNS by:
- Crossing the blood-brain barrier through the fenestrated endothelium of the blood vessels
- Using Trojan horse mechanisms, such as infected macrophages or leukocytes
- Exploiting the compromised integrity of the blood-brain barrier due to inflammation or trauma
Portals of Infection
- The following are portals of infection for the CNS: bloodstream, direct trauma, and contiguous spread from adjacent infected tissues.
- The eye is NOT a portal of infection for the CNS.
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