Metastatic Breast Cancer and Primary Adrenal Insufficiency
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Questions and Answers

What is the most common site of metastatic cancer spread to the adrenal glands?

  • Kidney
  • Skin (melanoma)
  • Breast
  • Lung (correct)

Which manifestation reflects adrenocortical destruction in primary adrenal insufficiency?

  • Hypertension and hypokalemia
  • Hypovolemia and hyperkalemia (correct)
  • Hyponatremia and hypercalcemia
  • Hypotension and hypoglycemia

What contributes to hyponatremia in primary adrenal insufficiency?

  • Reduced cortisol levels (correct)
  • Excessive potassium retention
  • Enhanced ADH secretion
  • Increased aldosterone production

Which hormone helps enhance vascular tone and is reduced in primary adrenal insufficiency?

<p>Cortisol (B)</p> Signup and view all the answers

What is the synthetic form of ACTH used in cosyntropin stimulation testing?

<p>Cortisol (C)</p> Signup and view all the answers

What happens with the absence of the expected increase in cortisol levels following cosyntropin administration?

<p>Adrenocortical destruction (B)</p> Signup and view all the answers

What contributes to renal sodium wasting and potassium retention in primary adrenal insufficiency?

<p>Reduced aldosterone production (D)</p> Signup and view all the answers

What can reduced cortisol production trigger in primary adrenal insufficiency?

<p>Hyperglycemia (D)</p> Signup and view all the answers

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