Metastatic Breast Cancer and Primary Adrenal Insufficiency

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8 Questions

What is the most common site of metastatic cancer spread to the adrenal glands?

Lung

Which manifestation reflects adrenocortical destruction in primary adrenal insufficiency?

Hypovolemia and hyperkalemia

What contributes to hyponatremia in primary adrenal insufficiency?

Reduced cortisol levels

Which hormone helps enhance vascular tone and is reduced in primary adrenal insufficiency?

Cortisol

What is the synthetic form of ACTH used in cosyntropin stimulation testing?

Cortisol

What happens with the absence of the expected increase in cortisol levels following cosyntropin administration?

Adrenocortical destruction

What contributes to renal sodium wasting and potassium retention in primary adrenal insufficiency?

Reduced aldosterone production

What can reduced cortisol production trigger in primary adrenal insufficiency?

Hyperglycemia

This quiz covers the manifestations and causes of primary adrenal insufficiency (AI) resulting from metastatic breast cancer. Learn about the common sites of metastatic cancer spread and the manifestations reflecting adrenocortical destruction.

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