Breast Cancer Quiz
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Questions and Answers

Which treatment option will this patient receive before surgery?

  • TCH+P x 6 cycles (correct)
  • AI (+/- CDK 4/6 inhibitor)
  • Endo Rx < 1 yr
  • Neulasta for neutropenia

What is the prognosis for this patient with stage II disease?

  • 25%
  • 15% - 25%
  • 23%
  • 85% (correct)

What is the general approach for a breast cancer patient with metastatic disease?

  • Chemotherapy for HER2-
  • Trastuzumab + pertuzumab + taxane (correct)
  • Ovarian ablation + SERM + HER2 target Rx + Taxane
  • Endocrine therapy for <1 year

What type of breast cancer is this patient diagnosed with?

<p>ER-/HER2+ (D)</p> Signup and view all the answers

Which treatment is indicated for HER2+ metastatic breast cancer patients who have previously received trastuzumab and/or a taxane?

<p>Ado Trastuzumab Emtansine (Kadcyla®) (C)</p> Signup and view all the answers

Which therapy is a dual EGFR and ErbB2 inhibitor?

<p>Lapatinib (Tykerb) (D)</p> Signup and view all the answers

Which treatment is a HER2-targeted antibody and microtubule inhibitor conjugate?

<p>Ado Trastuzumab Emtansine (Kadcyla®) (B)</p> Signup and view all the answers

Which treatment is recommended for ER-/PR-/HER2(Triple Negative) Breast Cancer?

<p>Poly (ADP-ribose) polymerase (PARP) Inhibition (D)</p> Signup and view all the answers

Which is the most common cause of cancer death in women?

<p>Breast cancer (D)</p> Signup and view all the answers

Which stage of breast cancer involves tumor size greater than 5 cm?

<p>Stage III (D)</p> Signup and view all the answers

What is the molecular subtype of breast cancer characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2)?

<p>Triple Negative (D)</p> Signup and view all the answers

Which stage of breast cancer involves tumor size greater than 5 cm?

<p>Stage IIIB (D)</p> Signup and view all the answers

What is the molecular subtype of breast cancer characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2)?

<p>Triple Negative (ER-/PR-/HER2-) (C)</p> Signup and view all the answers

What is the most common cause of cancer death in women?

<p>Lung cancer (C)</p> Signup and view all the answers

Which is the recommended treatment for a pre-menopausal patient with stage II breast cancer, ER-negative, HER2-positive, and invasive ductal carcinoma?

<p>TCH+P X 6 cycles, followed by T+P for 1 year (C)</p> Signup and view all the answers

What is the most common side effect of olaparib (Lynparza) in patients with metastatic breast cancer?

<p>Anemia (A)</p> Signup and view all the answers

What is the estimated overall survival rate for patients with metastatic breast cancer?

<p>15% - 25% (C)</p> Signup and view all the answers

Which treatment option is recommended for patients with recurrent or stage IV ER+/HER2+ breast cancer who have been on endocrine therapy for less than 1 year?

<p>Ovarian ablation + HER2 target Rx + Taxane (A)</p> Signup and view all the answers

Which treatment is indicated as adjuvant therapy or metastatic HER2+ breast cancer, where trastuzumab has failed or is contraindicated?

<p>Ado Trastuzumab Emtansine (Kadcyla®) (B)</p> Signup and view all the answers

Which treatment is a competitive ATP inhibitor (small molecule kinase inhibitor) that inhibits both EGFR and ErbB2 (HER2)?

<p>Lapatinib (Tykerb) (C)</p> Signup and view all the answers

Which treatment is a HER2-targeted antibody and microtubule inhibitor conjugate, with trastuzumab directing the chemotherapy preferentially to tumor cells?

<p>Ado Trastuzumab Emtansine (Kadcyla®) (D)</p> Signup and view all the answers

Which treatment is a poly (ADP-ribose) polymerase (PARP) inhibitor that is recommended to test for BRCA status and PDL1 expression in triple-negative breast cancer?

<p>Pertuzumab (Perjeta®) (B)</p> Signup and view all the answers

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