22 Questions
Which treatment option will this patient receive before surgery?
TCH+P x 6 cycles
What is the prognosis for this patient with stage II disease?
85%
What is the general approach for a breast cancer patient with metastatic disease?
Trastuzumab + pertuzumab + taxane
What type of breast cancer is this patient diagnosed with?
ER-/HER2+
Which treatment is indicated for HER2+ metastatic breast cancer patients who have previously received trastuzumab and/or a taxane?
Ado Trastuzumab Emtansine (Kadcyla®)
Which therapy is a dual EGFR and ErbB2 inhibitor?
Lapatinib (Tykerb)
Which treatment is a HER2-targeted antibody and microtubule inhibitor conjugate?
Ado Trastuzumab Emtansine (Kadcyla®)
Which treatment is recommended for ER-/PR-/HER2(Triple Negative) Breast Cancer?
Poly (ADP-ribose) polymerase (PARP) Inhibition
Which is the most common cause of cancer death in women?
Breast cancer
Which stage of breast cancer involves tumor size greater than 5 cm?
Stage III
What is the molecular subtype of breast cancer characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2)?
Triple Negative
Which stage of breast cancer involves tumor size greater than 5 cm?
Stage IIIB
What is the molecular subtype of breast cancer characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2)?
Triple Negative (ER-/PR-/HER2-)
What is the most common cause of cancer death in women?
Lung cancer
Which is the recommended treatment for a pre-menopausal patient with stage II breast cancer, ER-negative, HER2-positive, and invasive ductal carcinoma?
TCH+P X 6 cycles, followed by T+P for 1 year
What is the most common side effect of olaparib (Lynparza) in patients with metastatic breast cancer?
Anemia
What is the estimated overall survival rate for patients with metastatic breast cancer?
15% - 25%
Which treatment option is recommended for patients with recurrent or stage IV ER+/HER2+ breast cancer who have been on endocrine therapy for less than 1 year?
Ovarian ablation + HER2 target Rx + Taxane
Which treatment is indicated as adjuvant therapy or metastatic HER2+ breast cancer, where trastuzumab has failed or is contraindicated?
Ado Trastuzumab Emtansine (Kadcyla®)
Which treatment is a competitive ATP inhibitor (small molecule kinase inhibitor) that inhibits both EGFR and ErbB2 (HER2)?
Lapatinib (Tykerb)
Which treatment is a HER2-targeted antibody and microtubule inhibitor conjugate, with trastuzumab directing the chemotherapy preferentially to tumor cells?
Ado Trastuzumab Emtansine (Kadcyla®)
Which treatment is a poly (ADP-ribose) polymerase (PARP) inhibitor that is recommended to test for BRCA status and PDL1 expression in triple-negative breast cancer?
Pertuzumab (Perjeta®)
Test your knowledge about breast cancer, the most frequently diagnosed solid tumor in women. Learn about the latest statistics, risk factors, and staging system. Find out how deaths due to breast cancer are declining and the importance of early detection. Take the quiz now!
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