Metabolism of Carbohydrates and ATP Formation
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Questions and Answers

Which product is formed when glucose undergoes conversion in the pentose phosphate pathway?

  • Lactic acid
  • Pyruvic acid
  • Acetyl-CoA
  • D-ribulose (correct)
  • What is the primary fate of pyruvic acid under anaerobic conditions?

  • Conversion into lactic acid (correct)
  • Conversion into ethanol
  • Conversion into glucose
  • Conversion into acetyl-CoA
  • How many molecules of glucose are resynthesized for every six molecules that enter the pentose phosphate pathway?

  • 6
  • 4
  • 3
  • 5 (correct)
  • What role does lactic acid play in the metabolic process described?

    <p>Sinkhole</p> Signup and view all the answers

    What is the significance of glucose-6-phosphate in energy metabolism?

    <p>It can be converted into glycogen or fat</p> Signup and view all the answers

    What is the duration of energy supply provided by glycogen storage in the body?

    <p>12 to 24 hours</p> Signup and view all the answers

    In the pentose phosphate pathway, which process primarily uses five-carbon sugars?

    <p>Recycling to synthesize glucose</p> Signup and view all the answers

    What are the principal byproducts of glucose metabolism in the pentose phosphate pathway?

    <p>Lactic acid and carbon dioxide</p> Signup and view all the answers

    What is the primary function of glycogenolysis in the liver during fasting?

    <p>To convert stored glycogen to glucose</p> Signup and view all the answers

    Which process contributes approximately 25% of the liver's glucose production during fasting?

    <p>Gluconeogenesis</p> Signup and view all the answers

    During prolonged fasting, which organ also significantly contributes to glucose synthesis?

    <p>Kidneys</p> Signup and view all the answers

    What is the significance of NADP+ in the pentose phosphate pathway?

    <p>It generates NADPH for anabolic reactions</p> Signup and view all the answers

    What is the main purpose of the citric acid cycle?

    <p>To degrade acetyl-CoA to carbon dioxide and hydrogen atoms</p> Signup and view all the answers

    Which of the following correctly describes the conversion of alanine in gluconeogenesis?

    <p>Alanine is deaminated to form pyruvic acid, which can be converted into glucose</p> Signup and view all the answers

    Where do the reactions of the citric acid cycle occur within the cell?

    <p>In the matrix of mitochondria</p> Signup and view all the answers

    What percentage of amino acids in body proteins can be easily converted into carbohydrates?

    <p>60%</p> Signup and view all the answers

    Which compound is regenerated at the end of the citric acid cycle?

    <p>Oxaloacetic acid</p> Signup and view all the answers

    Which intermediate is often produced from amino acids that is crucial for glucose metabolism?

    <p>Pyruvic acid</p> Signup and view all the answers

    How many molecules of ATP are formed through the oxidation of hydrogen atoms released in the cycle?

    <p>Six</p> Signup and view all the answers

    What happens to the hydrogen produced during the pentose phosphate pathway?

    <p>It enters the oxidative phosphorylation pathway to form ATP</p> Signup and view all the answers

    What type of energy is ultimately released during the oxidation of hydrogen atoms in the citric acid cycle?

    <p>Chemical energy</p> Signup and view all the answers

    Which stage in glucose metabolism follows glycolysis?

    <p>Citric acid cycle</p> Signup and view all the answers

    What role does oxaloacetic acid play in the citric acid cycle?

    <p>It acts as an input substrate</p> Signup and view all the answers

    Which of the following is NOT a product of the citric acid cycle?

    <p>Lactate</p> Signup and view all the answers

    <h1>=</h1> <h1>=</h1> Signup and view all the answers

    Study Notes

    Metabolism of Carbohydrates and Formation of Adenosine Triphosphate

    • Metabolism encompasses the chemical processes essential for cellular life
    • This study focuses on carbohydrate metabolism and ATP formation
    • ATP (adenosine triphosphate) is the body's energy currency
    • ATP links energy-producing and energy-utilizing functions
    • ATP consists of adenine, ribose, and three phosphate radicals
    • High-energy bonds within ATP (indicated by ~) store energy
    • Breaking these bonds releases 12,000 calories per phosphate radical (standard conditions)
    • Glucose is the major carbohydrate for energy production in the body
    • Glucose is primarily converted to ATP in the cytoplasm and nucleus

    Release of Energy from Foods

    • Energy foods (carbohydrates, fats, and proteins) can be oxidized in cells
    • Oxidizing these foods releases energy, but in cells, it's released slowly
    • "Free energy" (AG) is the amount of energy liberated during complete oxidation
    • Free energy is expressed in calories per mole of substance
    • Example: Complete oxidation of 1 mole of glucose releases 686,000 calories

    Central Role of Glucose

    • Glucose is the primary end product of carbohydrate digestion
    • After absorption, fructose and galactose are quickly transformed into glucose
    • Transport through cell membranes is essential for glucose utilization
    • Glucose transport occurs through facilitated diffusion
    • Insulin significantly increases glucose transport into most cells

    Glycogen Storage

    • Glycogen is a large polymer of glucose, stored in liver and muscle cells
    • Glycogen storage allows for readily available energy
    • Glycogenolysis is the breakdown of glycogen to glucose
    • Glycogenesis is the process forming glycogen from glucose

    Glycolysis

    • Glycolysis is the breakdown of glucose into 2 molecules of pyruvic acid
    • This process occurs via a 10-step enzymatic pathway
    • Glycolysis releases energy, resulting in the formation of ATP molecules
    • Glycolysis yields 2 ATP molecules for every glucose molecule broken down

    Citric Acid Cycle

    • The citric acid cycle (also known as the Krebs cycle) further breaks down the acetyl-CoA molecules
    • This process occurs in the mitochondrial matrix
    • The cycle generates ATP and hydrogen atoms
    • The cycle releases carbon dioxide as a waste product

    Oxidative Phosphorylation

    • Oxidative phosphorylation is where most ATP is produced
    • Hydrogen atoms bind with NAD+ (nicotinamide adenine dinucleotide), forming NADH
    • Electrons from NADH pass through an electron transport chain, creating an electrochemical gradient
    • This gradient drives ATP formation, using ATP synthase
    • This process requires oxygen and is extremely efficient, producing significantly more ATP than glycolysis or the citric acid cycle

    Anaerobic Glycolysis

    • Anaerobic glycolysis occurs in the absence of oxygen
    • Pyruvic acid is converted to lactic acid, conserving some energy in this situation
    • Lactic acid can then be reconverted to pyruvic acid and used for energy when oxygen becomes available

    Pentose Phosphate Pathway

    • The pentose phosphate pathway is another way to break down glucose
    • It's important for producing NADPH (a key component in various metabolic reactions) and for generating certain sugars, as well as some precursors for nucleotide synthesis

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    Description

    This quiz explores the metabolism of carbohydrates and the formation of adenosine triphosphate (ATP), the energy currency of the body. You'll learn about the chemical processes involved in energy production and the role of glucose in ATP synthesis.

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