Podcast
Questions and Answers
During the absorptive or fed state, what is the primary energy source utilized by all tissues?
During the absorptive or fed state, what is the primary energy source utilized by all tissues?
What metabolic event is stimulated by the high insulin/glucagon ratio during the absorptive state?
What metabolic event is stimulated by the high insulin/glucagon ratio during the absorptive state?
In the fed state, what happens if there is excess glucose for storage?
In the fed state, what happens if there is excess glucose for storage?
What occurs to amino acid levels in the blood after a meal in the fed state?
What occurs to amino acid levels in the blood after a meal in the fed state?
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During the post-absorptive or fasting state, what major changes in metabolism occur?
During the post-absorptive or fasting state, what major changes in metabolism occur?
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What does the body regulate based on food intake?
What does the body regulate based on food intake?
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During the fed state, what do increased blood levels of glucose and amino acids stimulate the pancreas to release?
During the fed state, what do increased blood levels of glucose and amino acids stimulate the pancreas to release?
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What role does lipogenesis play in the metabolism in the fed state?
What role does lipogenesis play in the metabolism in the fed state?
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Which metabolic pathways are involved during the fed state in processing protein, fat, and carbohydrates into their component building blocks?
Which metabolic pathways are involved during the fed state in processing protein, fat, and carbohydrates into their component building blocks?
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In which circulation are the compounds processed by intestinal epithelial cells released during the fed state?
In which circulation are the compounds processed by intestinal epithelial cells released during the fed state?
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Study Notes
Absorptive/Fed State Metabolism
- Primary energy source for all tissues is glucose during the absorptive state.
- High insulin/glucagon ratio promotes glycogen synthesis, facilitating storage of glucose.
- Excess glucose in the fed state is converted to fat via lipogenesis for long-term energy storage.
- Amino acid levels in the blood rise after a meal, supporting protein synthesis and tissue repair.
Post-Absorptive/Fasting State Metabolism
- Metabolism shifts from storing energy to mobilizing energy reserves, with increased gluconeogenesis and fatty acid oxidation.
- Body regulates blood glucose levels based on food intake to maintain homeostasis.
- Elevated blood levels of glucose and amino acids post-meal stimulate pancreatic release of insulin, promoting nutrient uptake.
Lipogenesis Role
- Lipogenesis is crucial for converting excess dietary carbohydrates into triglycerides, stored in adipose tissues for future energy use.
Metabolic Pathways
- In the fed state, carbohydrates are broken down into glucose, fats into fatty acids, and proteins into amino acids through digestion.
- Intestinal epithelial cells release processed compounds into the portal circulation, directing them to the liver for further metabolism.
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Description
Test your knowledge on metabolism regulation in the fed state, fasting state, and during starvation. Topics include energy fuels, carbohydrate intake, and metabolic processes. Learn from Dr. Hend Yassin, a lecturer of medical biochemistry and molecular biology.
