Meningitis: Causes and Clinical Manifestations
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Questions and Answers

What is the term for the ability of a pathogen to spread to adjacent tissues?

  • Colonization
  • Penetration
  • Infectivity
  • Invasiveness (correct)

Which type of penetration occurs through the production of lytic substances that alter host tissue?

  • Active penetration (correct)
  • Cellular penetration
  • Passive penetration
  • Extracellular penetration

What is the term for the presence of viable bacteria in the blood?

  • Bacteremia (correct)
  • Endotoxin
  • Toxigenicity
  • Septicemia

Which type of exotoxin destroys cardiac, kidney, and nervous tissues by inhibiting protein synthesis?

<p>AB toxin (A)</p> Signup and view all the answers

What is the specific host site exotoxin associated with two subunit types A and B?

<p>AB toxin (D)</p> Signup and view all the answers

Which toxin disrupts the normal metabolism of host cells?

<p>Toxin (B)</p> Signup and view all the answers

Which pathogen causes Chlamydial Pneumonia?

<p>Chlamydophila pneumoniae (D)</p> Signup and view all the answers

What are mycotoxins?

<p>Toxins produced by fungi found in water-damaged buildings (B)</p> Signup and view all the answers

What is the first line of treatment for Chlamydial Pneumonia?

<p>Macrolides (D)</p> Signup and view all the answers

Which disease is caused by Legionella pneumophila?

<p>Legionnaires' Disease (A)</p> Signup and view all the answers

What is the major bacterial cause of epidemic meningitis?

<p>N.meningitidis (C)</p> Signup and view all the answers

How is bacterial meningitis diagnosed?

<p>Gram stain or culture of cerebrospinal fluid (CSF) (C)</p> Signup and view all the answers

What characteristic makes mycobacteria difficult to treat?

<p>Resistance to penetration of some antibiotics due to mycolic acid in cell wall (C)</p> Signup and view all the answers

How do Mycobacterium avium complex (MAC) infections commonly present in HIV-positive patients?

<p>Gastrointestinal infection (C)</p> Signup and view all the answers

What is the most common method for diagnosing Mycobacterium tuberculosis?

<p>Tuberculin Skin Test (A)</p> Signup and view all the answers

How is tuberculosis primarily transmitted?

<p>By respiratory droplets and aerosols (D)</p> Signup and view all the answers

What treatment approach is used for tuberculosis to decrease the development of drug resistance?

<p>Combination antimicrobial therapy with four drugs for 6 to 8 weeks, then two drugs for 6 months (B)</p> Signup and view all the answers

What characteristic differentiates N.meningitidis and Mycobacterium tuberculosis from each other?

<p>Mode of transmission (B)</p> Signup and view all the answers

Which bacterial infection is commonly observed in elderly patients with preexisting pulmonary disease or suppressed immune systems?

<p>Mycobacterium avium complex (MAC) infection (B)</p> Signup and view all the answers

What makes the spread of tuberculosis difficult to control?

<p>Reactivation tuberculosis due to bacteria reactivating at initial infection site (A)</p> Signup and view all the answers

What is the most effective method to control the spread of pertussis?

<p>Acellular vaccine with boosters (C)</p> Signup and view all the answers

Which of the following is a symptom of pertussis infection?

<p>Fever, malaise, uncontrollable cough, and cyanosis (C)</p> Signup and view all the answers

What is the causative agent of whooping cough?

<p>Gram-negative Bordetella pertussis (B)</p> Signup and view all the answers

Which bacterial toxin impacts electrolyte balance during pertussis infection?

<p>Pertussis toxin (C)</p> Signup and view all the answers

What is the primary method for diagnosing streptococcal pharyngitis?

<p>Rapid test kits (D)</p> Signup and view all the answers

Which streptococcal enzyme breaks down host molecules?

<p>Streptokinases (C)</p> Signup and view all the answers

What is the most common cause of permanent heart valve damage in children?

<p>Rheumatic fever (C)</p> Signup and view all the answers

Which stage of pertussis infection is characterized by prolonged coughing sieges?

<p>Paroxysmal stage (C)</p> Signup and view all the answers

How can streptococcal diseases like strep throat be spread?

<p>By droplets of saliva or nasal secretions (A)</p> Signup and view all the answers

What is the main reason for the reduction in homelessness and drug abuse in controlling the spread of pertussis?

<p>It reduces the number of susceptible individuals in the population (C)</p> Signup and view all the answers

What is the incubation period of an infectious disease?

<p>The time between pathogen entry and development of signs and symptoms (C)</p> Signup and view all the answers

Which type of pathogen only grows inside host cells?

<p>Obligate intracellular pathogen (B)</p> Signup and view all the answers

What is the role of a vector in spreading disease?

<p>Transferring infectious agent between hosts (D)</p> Signup and view all the answers

Which factor affects the success of transmission in terms of the number of invading organisms?

<p>Infectious dose 50 (ID50) (A)</p> Signup and view all the answers

What is tropism in the context of infectious diseases?

<p>The pathogen's need to make contact with appropriate host tissue (B)</p> Signup and view all the answers

Which type of pathogen may be part of normal microbiota but causes disease when the host is immunocompromised?

<p>Opportunistic pathogen (B)</p> Signup and view all the answers

What is the infectious dose 50 (ID50) used to measure?

<p>Number of invading organisms (B)</p> Signup and view all the answers

During which stage is the disease most severe and displays disease-specific signs and symptoms?

<p>Illness period (A)</p> Signup and view all the answers

What term is used for an organism that spreads disease from one host to another?

<p>Vector (C)</p> Signup and view all the answers

What are the characteristics of dormant pathogens that cause disease when the host is immunocompromised?

<p>They are classified as opportunistic pathogens (D)</p> Signup and view all the answers

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