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Questions and Answers
Which of the following is NOT a type of connective tissue?
Which of the following is NOT a type of connective tissue?
What is the primary function of connective tissue?
What is the primary function of connective tissue?
Which type of connective tissue is characterized by its dense, tightly packed fibers, offering high tensile strength?
Which type of connective tissue is characterized by its dense, tightly packed fibers, offering high tensile strength?
What is the main component of the extracellular matrix of connective tissue?
What is the main component of the extracellular matrix of connective tissue?
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Which type of connective tissue is found in the ears, nose, and trachea, providing flexibility and support?
Which type of connective tissue is found in the ears, nose, and trachea, providing flexibility and support?
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What is the term for the specialized cells that produce fibers and ground substance in connective tissue?
What is the term for the specialized cells that produce fibers and ground substance in connective tissue?
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What is the function of elastin in connective tissue?
What is the function of elastin in connective tissue?
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Which of the following connective tissues is primarily responsible for the body's ability to withstand pulling forces?
Which of the following connective tissues is primarily responsible for the body's ability to withstand pulling forces?
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What is the non-cellular component of connective tissue called?
What is the non-cellular component of connective tissue called?
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What is the function of collagen fibers in connective tissue?
What is the function of collagen fibers in connective tissue?
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Which type of fiber in connective tissue is responsible for providing elasticity?
Which type of fiber in connective tissue is responsible for providing elasticity?
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What is the main function of the ground substance in connective tissue?
What is the main function of the ground substance in connective tissue?
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Which of these options is responsible for determining the properties of different types of connective tissue?
Which of these options is responsible for determining the properties of different types of connective tissue?
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Which of the following statements is true about connective tissue?
Which of the following statements is true about connective tissue?
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Which type of fiber forms a network for support in connective tissue?
Which type of fiber forms a network for support in connective tissue?
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What is the main goal of the inflammatory phase of wound healing?
What is the main goal of the inflammatory phase of wound healing?
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Which of the following is NOT a characteristic of inflammation?
Which of the following is NOT a characteristic of inflammation?
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Which of the following chemicals is NOT a key inflammatory mediator?
Which of the following chemicals is NOT a key inflammatory mediator?
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What does vasodilation, a result of inflammatory mediators, directly cause in the wound area?
What does vasodilation, a result of inflammatory mediators, directly cause in the wound area?
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What effect does increased permeability of blood vessels, caused by inflammatory mediators, have on the wound?
What effect does increased permeability of blood vessels, caused by inflammatory mediators, have on the wound?
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What is the primary role of white blood cells in the inflammatory phase of wound healing?
What is the primary role of white blood cells in the inflammatory phase of wound healing?
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How long does the inflammatory phase typically last?
How long does the inflammatory phase typically last?
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Which of the following is NOT a factor that can trigger an inflammatory response?
Which of the following is NOT a factor that can trigger an inflammatory response?
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Which type of collagen provides high tensile strength, stronger than steel, and is found in bone, tendons, ligaments, and skin?
Which type of collagen provides high tensile strength, stronger than steel, and is found in bone, tendons, ligaments, and skin?
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What is the primary function of proteoglycans in the extracellular matrix?
What is the primary function of proteoglycans in the extracellular matrix?
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What is the relationship between glycosaminoglycans (GAGs) and proteoglycans?
What is the relationship between glycosaminoglycans (GAGs) and proteoglycans?
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Which of the following is NOT a component of the extracellular matrix (ECM)?
Which of the following is NOT a component of the extracellular matrix (ECM)?
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How do proteoglycans contribute to the stability of collagen fibers?
How do proteoglycans contribute to the stability of collagen fibers?
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Which type of collagen is primarily found in cartilage?
Which type of collagen is primarily found in cartilage?
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What is the main difference between the ECM in loose connective tissue and dense connective tissue?
What is the main difference between the ECM in loose connective tissue and dense connective tissue?
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What is the role of hyaluronan in proteoglycan aggregates?
What is the role of hyaluronan in proteoglycan aggregates?
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What is the primary goal of functional exercise during the proliferative phase of wound healing?
What is the primary goal of functional exercise during the proliferative phase of wound healing?
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Which phase of wound healing follows the inflammatory phase?
Which phase of wound healing follows the inflammatory phase?
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During the remodeling phase of wound healing, what type of collagen replaces type III collagen?
During the remodeling phase of wound healing, what type of collagen replaces type III collagen?
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What activity should a physiotherapist encourage during the remodeling phase of wound healing?
What activity should a physiotherapist encourage during the remodeling phase of wound healing?
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What is the purpose of cross-linking in the remodeling phase of wound healing?
What is the purpose of cross-linking in the remodeling phase of wound healing?
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What effect does increased permeability have on surrounding tissues?
What effect does increased permeability have on surrounding tissues?
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What is the primary purpose of white blood cells (WBC) during inflammation?
What is the primary purpose of white blood cells (WBC) during inflammation?
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Which phase of wound healing involves the formation of granulation tissue?
Which phase of wound healing involves the formation of granulation tissue?
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What specific process do fibroblasts undergo during the proliferative phase?
What specific process do fibroblasts undergo during the proliferative phase?
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What type of collagen is primarily produced during the initial stages of the proliferative phase?
What type of collagen is primarily produced during the initial stages of the proliferative phase?
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What is the main purpose of angiogenesis in the wound healing process?
What is the main purpose of angiogenesis in the wound healing process?
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During which phase of wound healing does the extracellular matrix (ECM) begin to form?
During which phase of wound healing does the extracellular matrix (ECM) begin to form?
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What is a key role of fibroblasts in the context of tissue healing?
What is a key role of fibroblasts in the context of tissue healing?
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Flashcards
Functional exercises
Functional exercises
Lightly load movements to promote healing and strengthen tissue.
Inflammatory phase
Inflammatory phase
The first stage of wound healing lasting 1-5 days, characterized by inflammation.
Proliferative phase
Proliferative phase
The stage of wound healing from 5-21 days where tissue formation occurs.
Remodeling phase
Remodeling phase
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Collagen types in healing
Collagen types in healing
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Connective Tissue
Connective Tissue
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Types of Tissues
Types of Tissues
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Epithelial Tissue
Epithelial Tissue
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Nervous Tissue
Nervous Tissue
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Muscle Tissue
Muscle Tissue
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Types of Connective Tissue
Types of Connective Tissue
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Dense Connective Tissue
Dense Connective Tissue
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Healing Phases of Wound Healing
Healing Phases of Wound Healing
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White Blood Cells (WBC)
White Blood Cells (WBC)
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Increased Permeability
Increased Permeability
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Inflammatory Mediators
Inflammatory Mediators
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Fibroblasts
Fibroblasts
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Extracellular Matrix (ECM)
Extracellular Matrix (ECM)
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Angiogenesis
Angiogenesis
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Wound Healing
Wound Healing
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Characteristics of Inflammation
Characteristics of Inflammation
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Vasodilatation
Vasodilatation
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Type I collagen
Type I collagen
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Type II collagen
Type II collagen
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Proteoglycans
Proteoglycans
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Glycosaminoglycans (GAGs)
Glycosaminoglycans (GAGs)
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Tensile strength
Tensile strength
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Proteoglycan aggregates
Proteoglycan aggregates
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Viscosity
Viscosity
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Components of Connective Tissue
Components of Connective Tissue
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Collagen Fibers
Collagen Fibers
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Elastin Fibers
Elastin Fibers
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Reticulin Fibers
Reticulin Fibers
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Ground Substance
Ground Substance
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Study Notes
Medical-Biological Lecture Notes
- The lecture is about connective tissue and wound healing.
- There are seven lectures in total.
- Lecture 1: Connective tissue and wound healing.
- Lecture 2: Pain, part I.
- Lecture 3: Bone tissue and fractures.
- Lecture 4: Shoulder anatomy.
- Lecture 5: Frozen shoulder (knowledge clip).
- Lecture 6: Spine (physical) + osteoarthritis (knowledge clip).
- Lecture 7: Tendons and tendinopathy + pain part II.
Common Terms in Connective Tissue
- Fibroblasts
- Extracellular matrix
- Tissue
- Cells
- Proteoglycans
- Ground substance
- Collagen
- Cross-links
- Aggregates
- Elastine
- Reticuline
- Glycosaminoglycans
- Dense connective tissue
- Loose connective tissue
Learning Objectives
- Describe the function and composition and structure of various tissues.
- Explain what happens during inflammation.
- Explain what happens during the different phases of wound healing.
Tissue Types
- Tissue = a group of similar cells that work together to perform a common function.
- Four types of tissue:
- Epithelial tissue: Covers body cavities and protects against damage and dehydration.
- Connective tissue: Fills in spaces, protects and insulates, and provides support to the body.
- Muscle tissue: Allows movement of body parts through contraction.
- Nervous tissue: Composed of nerve cells, carrying information throughout the body.
Connective Tissue Types
- Loose connective tissue (under the skin)
- Adipose tissue
- Blood
- Dense connective tissue (ligaments)
- Cartilage (at the end of a bone)
- Bone
- Dense connective tissue (tendons, ligaments, capsules)
- Loose connective tissue (fat, connective tissue around organs)
- Cartilage
- Blood
Connective Tissue - Structure
- Connective tissue consists of cells and extracellular matrix (ECM).
- ECM: Non-cellular components of connective tissue.
- Fibres (collagen, elastin, reticulin).
- Ground substance (proteoglycans).
Connective Tissue - Fiber Types
- Collagen (strength)
- Elastin (elasticity)
- Reticulin (network/filling)
Connective Tissue - Collagen Types
- Type I: Bone, tendon, ligament, skin (high tensile strength, stronger than steel)
- Type II: Cartilage
- Type III: Wound healing, blood vessels, skin
Connective Tissue - Ground Substance - Proteoglycans
- Proteoglycans = protein + sugar chains.
- Combine protein and sugar.
- Binds water.
- More GAGs = higher viscosity (thicker).
- Stabilizes collagen fibers.
- Proteoglycans often form aggregates.
Wound Healing - 3 Phases
- Inflammatory phase (1-5 days)
- Proliferative phase (5-21 days)
- Remodeling phase (varies)
Wound Healing - Inflammatory Phase
- Reaction to tissue damage.
- Many possible causes: physical trauma, burns, irritants, infections.
- Goal: Prepare tissue for repair, prevent spread and remove debris.
- Coagulation Prevents spread.
- Removal: Damaged cell, matrix fragments, pathogens.
Inflammation Characteristics
- Heat (calor)
- Redness (rubor)
- Swelling (tumor)
- Pain (dolor)
- Loss of function (functio laesa)
Wound Healing - Inflammatory Mediators
- Substances released during tissue damage activating the inflammatory response:
- Histamine, kinins and prostaglandins.
Wound Healing - Proliferative Phase
- Create initial new tissue.
- Formation of new blood vessels (angiogenesis)
- Production of ECM by fibroblasts.
- Formation of granulation tissue .
Wound Healing - Remodeling Phase
- Reshape tissue to resemble the original tissue.
- Fibroblasts continue to form and remodel structure
- Collagen type III replaced by collagen type I
- Cross-linking increases tissue strength.
- Increasing functional load/stress/exercise can support the reformation process.
Additional Information and Summary
- Future lecture on pain.
- The notes are based on a medical-biological presentation.
- The information focuses on tissue types, function and structure, and wound healing.
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Description
This quiz focuses on the first lecture of a seven-part series, covering the structure, function, and types of connective tissue, as well as the phases of wound healing. Test your knowledge on key terms like fibroblasts, collagen, and the extracellular matrix, and understand the biological processes involved in inflammation and healing.