Tissue Remodelling in Wound Healing

What is the primary mechanism of repair when injury involves only the epithelial layer?

Which type of collagen is predominant during the early stages of wound healing?

What is the role of matrix metalloproteinases (MMPs) in tissue degradation?

What happens during wound healing by second intention?

Which process involves the synthesis of extracellular matrix (ECM) proteins?

What characterizes wound healing when there is extensive cell or tissue loss?

Which cellular component is responsible for the close of the wound by pulling margins to the center?

What is the main role of capillary loops in the wound healing process?

What is the function of vascular endothelial growth factors (VEGF) in wound healing?

Which characteristic is associated with mature scar tissue?

In which phase of wound healing do fibroblasts migrate towards the center and produce collagen?

What is the primary role of myofibroblasts in wound healing?

Which cell type is responsible for the contraction of myofibroblasts that reduces the volume of tissue during repair?

What is the main function of the extracellular matrix (ECM) in tissues?

What component of the ECM provides tissues with resilience and lubrication?

What factor is responsible for the conversion of granulation tissue scaffolding into a pale, avascular scar during wound healing?

What is the consequence of excessive contraction during repair that can occur in the gastrointestinal tract?

Which growth factor is primarily responsible for fibroblasts depositing extracellular matrix (ECM) during tissue repair?

What determines whether a wound heals by first or second intention?

In wound healing, what occurs during the proliferation phase?

What is the main function of granulation tissue in wound healing?

Why does wound contraction occur in large wounds?

During skin regeneration, what is lost as specialised tissues heal?

At what point does a wound reach about 70-80% strength during the healing process?

Which type of abnormal healing is more common in darker skin?

What is the main cause of deficient scar formation according to the text?

Which process leads to the replacement of normal tissue by fibrosis?

What term describes the process where an injury results in permanent damage causing dysfunction?

Which cells are described as labile, stable, or permanent/fixed in terms of their capacity for regeneration?

What is the key difference between healing by primary intention and healing by secondary intention?

Which type of cells are capable of proliferating continuously and maturing from tissue stem cells?

Which cells are described as terminally differentiated and nonproliferative postnatally?

Which stage of the cell cycle are stable (quiescent) cells typically in?

Which types of cells are capable of dividing in response to injury or loss of tissue mass?

Which type of cells are found in the parenchyma of most solid tissues like the liver, kidney, and pancreas?

Which cell type has minimal proliferative activity in normal state but is capable of dividing in response to injury?

What is the main consequence of excessive contraction during repair in the gastrointestinal tract?

Which growth factor plays a significant role in fibroblasts depositing extracellular matrix (ECM) during tissue repair?

What is the primary function of myofibroblasts during wound healing?

Which component of the extracellular matrix (ECM) provides tissues with resilience and lubrication?

What is a common problem that may arise from the contraction of granulation tissue during repair?

Why does depositing Extracellular matrix (ECM) become crucial as repair progresses?

Which type of abnormal healing is characterized by excessive scarring that grows rapidly but regresses?

What is the main consequence of persistent tissue injury according to the text?

Which cells play a key role in the deposition of collagen and other extracellular matrix (ECM) proteins during tissue repair?

What is the primary mechanism by which chronic inflammation leads to fibrosis?

Which type of injury may result in residual scarring according to the text?

What is the consequence of wound contraction in terms of joint mobility during repair?

What is the primary difference between labile and stable cells in terms of regeneration?

What role does the basement membrane play in the regeneration of damaged epithelial cells?

During which phase of repair does the formation of connective tissue deposited by fibroblasts occur?

What is the consequence of extensive tissue damage or damage to permanent/non-dividing cells during repair?

What is the primary function of granulation tissue in wound healing?

What characterizes the process of repair by scarring according to Dr. C.Hand?

What is the primary function of matrix metalloproteinases (MMPs) in tissue degradation during wound healing?

During wound healing, what characterizes the process when there is extensive cell or tissue loss?

Which type of wound healing involves the loss of tissue and unopposed wound edges?

What is the primary function of myofibroblasts in the wound healing process?

Which type of collagen is predominant during the early stages of wound healing?

What is the main role of granulation tissue in the wound healing process?