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Mechanism of Action of Morphine and Opioid Receptors

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What is the primary mechanism of action for morphine and related compounds?

They stimulate opioid receptors in the central nervous system and peripheral tissues

Which of the following are endogenous natural opioid peptides?

Endorphins, enkephalins, and dynorphins

Which opioid receptor type is primarily responsible for respiratory depression caused by morphine?

μ (mu) receptors

What is the primary effect of stimulating κ (kappa) opioid receptors?

Spinal analgesia and miosis

Which statement about substance P is correct in the context of morphine's mechanism of action?

Morphine inhibits the release of substance P, reducing pain sensation

Which of the following side effects is NOT directly related to opioid receptor stimulation by morphine?

Hyperthermia (increased body temperature)

Learn about how morphine and related compounds stimulate opioid receptors in the central nervous system and peripheral tissues to modulate pain sensation. Discover the role of endogenous natural opioid peptides such as endorphins, enkephalins, and dynorphins in binding to these receptors and regulating neurotransmitter release.

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