Major Histocompatibility Complex (MHC) Quiz
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Questions and Answers

Which type of pathogens do MHC class I molecules present peptide antigens derived from?

  • Pathogens that affect the immune system
  • Pathogens that replicate inside the cell, such as viruses (correct)
  • Pathogens that infect the bloodstream
  • Pathogens that are present outside the cell

From where do MHC class II molecules present peptides?

  • Pathogens that replicate inside the cell
  • Pathogens in the bloodstream
  • Pathogens affecting the immune system
  • Pathogens and antigens present outside the cell taken up by endocytic vesicles of phagocytic cells (correct)

What is the function of MHC class I molecules in the immune response?

  • Present peptide antigens derived from intracellular pathogens (correct)
  • Present peptide antigens derived from extracellular pathogens
  • Activate T cells
  • Produce antibodies

Which type of cells take up pathogens and antigens present outside the cell for presentation by MHC class II molecules?

<p>Phagocytic cells with endocytic vesicles (C)</p> Signup and view all the answers

What does MHC stand for?

<p>Major Histocompatibility Complex (C)</p> Signup and view all the answers

What is the function of MHC class I molecules in the immune response?

<p>Present peptide antigens derived from pathogens that replicate inside the cell (D)</p> Signup and view all the answers

Where do MHC class II molecules present peptides from?

<p>Pathogens and antigens present outside the cell taken up by endocytic vesicles of phagocytic cells (A)</p> Signup and view all the answers

What is the main function of the Major Histocompatibility Complex (MHC)?

<p>Present antigens to T cells (D)</p> Signup and view all the answers

How does MHC class II differ from MHC class I in terms of antigen presentation?

<p>Presents peptides from pathogens and antigens present outside the cell (C)</p> Signup and view all the answers

How is MHC polymorphism generated?

<p>Through genetic variation and recombination (D)</p> Signup and view all the answers

Flashcards

MHC Class I presentation

Presents antigens from intracellular pathogens, like viruses.

MHC Class II presentation

Presents antigens from pathogens outside the cell.

Intracellular pathogens

Pathogens that replicate inside cells.

Phagocytic cells

Cells that engulf pathogens and antigens.

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MHC function

Display antigens to T cells for immune response.

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Endocytic vesicles

Transport pathogens and antigens to MHC Class II.

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MHC

Major Histocompatibility Complex.

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MHC polymorphism

Genetic diversity in MHC molecules.

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Antigen presentation to T cells

MHC molecules display antigens to activate immune cells.

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MHC Class I vs Class II

Class I presents intracellular antigens; Class II presents extracellular antigens.

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