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Questions and Answers
What is the function of the integral membrane protein complexes on cell surfaces?
What is the function of the integral membrane protein complexes on cell surfaces?
- Regulating cell division
- Transporting nutrients into the cell
- Maintaining cell structure
- Recognizing antigens for lymphocytes (correct)
Where are MHC molecules made?
Where are MHC molecules made?
- Mitochondria
- Rough ER and Golgi apparatus (correct)
- Nucleus
- Cytoplasm
What is the role of MHC class I and class II molecules?
What is the role of MHC class I and class II molecules?
- Facilitating cell communication
- Producing energy for cells
- Presenting antigens to lymphocytes (correct)
- Promoting cell death
Study Notes
Integral Membrane Protein Complexes on Cell Surfaces
- Integral membrane protein complexes on cell surfaces play a crucial role in antigen presentation, enabling the immune system to recognize and respond to pathogens.
MHC Molecule Production
- MHC molecules are produced in the endoplasmic reticulum (ER) of cells.
MHC Class I and Class II Molecules
- MHC class I molecules are responsible for presenting endogenous antigens (from inside the cell) to CD8+ T cells, which then recognize and eliminate infected cells.
- MHC class II molecules, on the other hand, present exogenous antigens (from outside the cell) to CD4+ T cells, which activate other immune cells to respond to the pathogen.
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Test your knowledge of the major histocompatibility complex (MHC) and its role in presenting antigens to lymphocytes. Explore the structure and function of MHC class I and class II molecules, and their synthesis in the rough endoplasmic reticulum (ER) and Golgi apparatus.
