Lysosomes: Intracellular Digestion Organelles

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What do lysosomes primarily function as in a cell?

Digestive system (correct)

Protein synthesis machinery

Transport vesicles

Energy production centers

Which genetic diseases are characterized by the accumulation of undegraded material within lysosomes?

Lysosomal storage diseases (correct)

Cystic fibrosis

Mitochondrial diseases

Glycogen storage diseases

What is responsible for the acidic pH within lysosomes?

Glycosylated proteins

Hydrolytic enzymes

ATP synthesis machinery

Proton pump (correct)

Which type of polymers can be broken down by enzymes found in lysosomes?

All biological polymers Signup and view all the answers

What is the main consequence of mutations in genes encoding lysosomal enzymes?

Impaired degradation of cellular material Signup and view all the answers

Which process helps protect lysosomal membrane proteins from degradation?

Glycosylation Signup and view all the answers

What is the specific marker enzyme used to stain lysosomes in the electron micrographs?

Phosphatase Signup and view all the answers

What is the role of adaptins in the clathrin coat in the trans Golgi network?

Bind to M6P receptors Signup and view all the answers

What happens to the phosphate attached to mannose sugars in the late endosomes?

It is removed from the mannose sugars Signup and view all the answers

How are precursors of lysosomal hydrolases modified in the Golgi apparatus?

By the addition of mannose 6-phosphate groups Signup and view all the answers

What is the significance of the diverse morphology of lysosomes?

Reflects variations in the amount and nature of material being digested Signup and view all the answers

Which organelles contain dense precipitates of lead phosphate that are visible under electron microscopy?

Lysosomes Signup and view all the answers

Lysosomes: Intracellular Digestion Organelles

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