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Questions and Answers
What is the chief function of lysosomes?
Where are the hydrolytic enzymes in lysosomes manufactured?
What can excessive leakage from a large number of lysosomes result in?
How is the pH of endosomes lowered to less than 6?
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What type of molecules do lysosomal acidic hydrolytic enzymes break down?
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Study Notes
Lysosomes Function and Characteristics
- Chief function of lysosomes is to break down waste materials and cellular debris through enzymatic digestion.
- Hydrolytic enzymes within lysosomes are manufactured in the endoplasmic reticulum and processed through the Golgi apparatus.
- Excessive leakage from a large number of lysosomes can lead to cellular damage or cell death, due to uncontrolled release of hydrolytic enzymes into the cytoplasm.
- The pH of endosomes is lowered to less than 6 by the activity of proton pumps that transport hydrogen ions into the endosome.
- Lysosomal acidic hydrolytic enzymes break down various types of biological macromolecules, including proteins, lipids, carbohydrates, and nucleic acids.
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Description
Test your knowledge about lysosomes, the single membranous organelles containing various digestive enzymes manufactured in the endoplasmic reticulum. Understand the role of lysosomes in maintaining cell equilibrium and the consequences of their excessive leakage.
