Podcast
Questions and Answers
What is the primary function of the lymphoid system?
What is the primary function of the lymphoid system?
- To aid in digestion
- To produce red blood cells
- To regulate body temperature
- To protect the body against biological agents (correct)
Which organs are considered primary lymphoid organs in mammals?
Which organs are considered primary lymphoid organs in mammals?
- Peyer's patches and tonsils
- Bursa of Fabricius and haemolymph nodes
- Spleen and lymph nodes
- Bone marrow and thymus (correct)
What characterizes the secondary lymphoid organs?
What characterizes the secondary lymphoid organs?
- They produce hormones for the body
- They lack a capsule and are called mucosa-associated lymphoid tissue (MALT) (correct)
- They are involved in muscle coordination
- They store excess nutrients for the body
Which organ is of a lymphoepithelial nature?
Which organ is of a lymphoepithelial nature?
Where do T lymphocytes differentiate and undergo proliferation?
Where do T lymphocytes differentiate and undergo proliferation?
What type of cells produce polypeptides that support T cell differentiation and proliferation in the thymus?
What type of cells produce polypeptides that support T cell differentiation and proliferation in the thymus?
Which organ participates in B cell genesis and differentiation in birds?
Which organ participates in B cell genesis and differentiation in birds?
Which lymphoid organ has a rounded sac shape and is located near the cloaca in birds?
Which lymphoid organ has a rounded sac shape and is located near the cloaca in birds?
What happens to the Bursa of Fabricius approximately two months after birth?
What happens to the Bursa of Fabricius approximately two months after birth?
Which organ is responsible for B cell genesis and differentiation in mammals?
Which organ is responsible for B cell genesis and differentiation in mammals?
What type of cells present antigens to B cells in secondary follicles?
What type of cells present antigens to B cells in secondary follicles?
Which type of follicles consist of a reticular fiber network, reticular cells, follicular dendritic cells, and lodged B and T cells?
Which type of follicles consist of a reticular fiber network, reticular cells, follicular dendritic cells, and lodged B and T cells?
Where do TL-CFUs differentiate into T lymphocytes before colonizing the T areas of secondary lymphoid organs?
Where do TL-CFUs differentiate into T lymphocytes before colonizing the T areas of secondary lymphoid organs?
What is the function of the medulla in the thymus?
What is the function of the medulla in the thymus?
What is the function of the cortex in the thymus?
What is the function of the cortex in the thymus?
What is the primary function of mucosa-associated lymphoid tissue (MALT)?
What is the primary function of mucosa-associated lymphoid tissue (MALT)?
What are the primary constituents of the germinal center of secondary lymphoid follicles?
What are the primary constituents of the germinal center of secondary lymphoid follicles?
Where are Peyer's patches located?
Where are Peyer's patches located?
What type of lymphoid tissue are isolated lymphoid follicles in the bronchi a part of?
What type of lymphoid tissue are isolated lymphoid follicles in the bronchi a part of?
What type of cells primarily make up the mantle of secondary lymphoid follicles?
What type of cells primarily make up the mantle of secondary lymphoid follicles?
What are the tonsils primarily composed of?
What are the tonsils primarily composed of?
Which of the following is NOT a location for diffuse lymphocyte infiltrations?
Which of the following is NOT a location for diffuse lymphocyte infiltrations?
What different regions can be differentiated in Peyer's patches?
What different regions can be differentiated in Peyer's patches?
What is the primary role of isolated or groups of lymphoid follicles such as Peyer's patches?
What is the primary role of isolated or groups of lymphoid follicles such as Peyer's patches?
Apart from protecting the mucosa from pathogens, what is another function of mucosa-associated lymphoid tissue (MALT)?
Apart from protecting the mucosa from pathogens, what is another function of mucosa-associated lymphoid tissue (MALT)?
What lies below the epithelium in the tonsils?
What lies below the epithelium in the tonsils?
What structure consists of areas with deep invaginations called tonsillar crypts?
What structure consists of areas with deep invaginations called tonsillar crypts?
Where do the genesis and differentiation of the lymphoid cells take place, becoming immunocompetent?
Where do the genesis and differentiation of the lymphoid cells take place, becoming immunocompetent?
Which of the following is NOT considered a primary lymphoid organ in mammals?
Which of the following is NOT considered a primary lymphoid organ in mammals?
Which type of follicles consist of a reticular fiber network, reticular cells, follicular dendritic cells, and lodged B and T cells?
Which type of follicles consist of a reticular fiber network, reticular cells, follicular dendritic cells, and lodged B and T cells?
What are the secondary lymphoid organs encapsulated and form a true organ?
What are the secondary lymphoid organs encapsulated and form a true organ?
Which is the primary constituent of the germinal center of secondary lymphoid follicles?
Which is the primary constituent of the germinal center of secondary lymphoid follicles?
What characterizes the tonsils located on the tongue and oropharynx?
What characterizes the tonsils located on the tongue and oropharynx?
What lies below the epithelium in the tonsils?
What lies below the epithelium in the tonsils?
What type of cells primarily make up the mantle of secondary lymphoid follicles?
What type of cells primarily make up the mantle of secondary lymphoid follicles?
What characterizes large accumulations of lymphoid tissue associated with mucosa in the digestive system?
What characterizes large accumulations of lymphoid tissue associated with mucosa in the digestive system?
Where are Peyer's patches located?
Where are Peyer's patches located?
What is the function of the mucosa-associated lymphoid tissue (MALT) apart from protecting the mucosa from pathogens?
What is the function of the mucosa-associated lymphoid tissue (MALT) apart from protecting the mucosa from pathogens?
Which organ participates in B cell genesis and differentiation in mammals?
Which organ participates in B cell genesis and differentiation in mammals?
What are the primary constituents of the primary lymphoid organs in mammals?
What are the primary constituents of the primary lymphoid organs in mammals?
Which organ has a rounded sac shape and is located near the cloaca in birds?
Which organ has a rounded sac shape and is located near the cloaca in birds?
Which type of cells produce polypeptides that support T cell differentiation and proliferation in the thymus?
Which type of cells produce polypeptides that support T cell differentiation and proliferation in the thymus?
Where do TL-CFUs differentiate into T lymphocytes before colonizing the T areas of secondary lymphoid organs?
Where do TL-CFUs differentiate into T lymphocytes before colonizing the T areas of secondary lymphoid organs?
What is the primary function of the medulla in the thymus?
What is the primary function of the medulla in the thymus?
Where do T lymphocytes differentiate and undergo proliferation?
Where do T lymphocytes differentiate and undergo proliferation?
Which type of cells primarily make up the mantle of secondary lymphoid follicles?
Which type of cells primarily make up the mantle of secondary lymphoid follicles?
Where are Peyer's patches located?
Where are Peyer's patches located?
What different regions can be differentiated in Peyer's patches?
What different regions can be differentiated in Peyer's patches?
Which organ participates in B cell genesis and differentiation in birds?
Which organ participates in B cell genesis and differentiation in birds?
What is the function of the cortex in the thymus?
What is the function of the cortex in the thymus?
Which organ is responsible for B cell genesis and differentiation in mammals?
Which organ is responsible for B cell genesis and differentiation in mammals?
What is the primary function of mucosa-associated lymphoid tissue (MALT)?
What is the primary function of mucosa-associated lymphoid tissue (MALT)?
What lies below the epithelium in the tonsils?
What lies below the epithelium in the tonsils?
What are the secondary lymphoid organs encapsulated and form a true organ?
What are the secondary lymphoid organs encapsulated and form a true organ?
What type of cells produce polypeptides that support T cell differentiation and proliferation in the thymus?
What type of cells produce polypeptides that support T cell differentiation and proliferation in the thymus?
Study Notes
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The thymus is a lobed parenchymal organ where T lymphocytes differentiate and undergo proliferation, independent of antigenic stimulation.
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TL-CFUs differentiate into T lymphocytes in the thymus and leave to colonize the T areas of secondary lymphoid organs.
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The thymus develops earlier than other lymphoid organs (e.g., spleen and lymph nodes).
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Each thymic lobe is surrounded by a thin capsule of connective tissue and subdivided into lobules (pseudolobules) with a cortex and medulla.
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The cortex, made of T cells and macrophages, contains large lymphocytes (immature T cells) that undergo proliferation and are tested for self-recognition.
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The medulla, made of differentiated T cells and macrophages, contains reticulo-epithelial cells (stellate-shaped cells), interdigitating cells (antigen-presenting cells), and Hassall's corpuscles.
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Reticulo-epithelial cells produce polypeptides that support T cell differentiation and proliferation.
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The cortex contains a continuous capillary barrier, the blood-thymus barrier, which prevents differentiating lymphocytes from contacting antigens.
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The thymus undergoes involution, transforming into a mass of adipose tissue with few remaining lymphocytes and reticulo-epithelial cells.
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The Bursa of Fabricius is a lymphoepithelial organ in birds that participates in B cell genesis and differentiation, with a functional equivalent being the bone marrow.
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The Bursa of Fabricius has a rounded sac shape and is located near the cloaca, with mucosa folds containing columnar pseudostratified epithelium and lymphoid follicles.
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Each follicle has a cortex and medulla, and undergoes involution approximately two months after birth.
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Primary lymphoid organs, such as the bone marrow, are responsible for B cell genesis and differentiation in mammals.
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Secondary lymphoid organs contain lymphoid follicles, with primary and secondary follicles differing in morphology and function.
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Primary follicles consist of a reticular fiber network, reticular cells, follicular dendritic cells, and lodged B and T cells.
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Follicular dendritic cells present antigens to B cells.
-
Secondary follicles are formed after antigenic stimulation and contain germinal centers where B cells undergo somatic hypermutation and class switch recombination.
-
The thymus is a lobed parenchymal organ where T lymphocytes differentiate and undergo proliferation, independent of antigenic stimulation.
-
TL-CFUs differentiate into T lymphocytes in the thymus and leave to colonize the T areas of secondary lymphoid organs.
-
The thymus develops earlier than other lymphoid organs (e.g., spleen and lymph nodes).
-
Each thymic lobe is surrounded by a thin capsule of connective tissue and subdivided into lobules (pseudolobules) with a cortex and medulla.
-
The cortex, made of T cells and macrophages, contains large lymphocytes (immature T cells) that undergo proliferation and are tested for self-recognition.
-
The medulla, made of differentiated T cells and macrophages, contains reticulo-epithelial cells (stellate-shaped cells), interdigitating cells (antigen-presenting cells), and Hassall's corpuscles.
-
Reticulo-epithelial cells produce polypeptides that support T cell differentiation and proliferation.
-
The cortex contains a continuous capillary barrier, the blood-thymus barrier, which prevents differentiating lymphocytes from contacting antigens.
-
The thymus undergoes involution, transforming into a mass of adipose tissue with few remaining lymphocytes and reticulo-epithelial cells.
-
The Bursa of Fabricius is a lymphoepithelial organ in birds that participates in B cell genesis and differentiation, with a functional equivalent being the bone marrow.
-
The Bursa of Fabricius has a rounded sac shape and is located near the cloaca, with mucosa folds containing columnar pseudostratified epithelium and lymphoid follicles.
-
Each follicle has a cortex and medulla, and undergoes involution approximately two months after birth.
-
Primary lymphoid organs, such as the bone marrow, are responsible for B cell genesis and differentiation in mammals.
-
Secondary lymphoid organs contain lymphoid follicles, with primary and secondary follicles differing in morphology and function.
-
Primary follicles consist of a reticular fiber network, reticular cells, follicular dendritic cells, and lodged B and T cells.
-
Follicular dendritic cells present antigens to B cells.
-
Secondary follicles are formed after antigenic stimulation and contain germinal centers where B cells undergo somatic hypermutation and class switch recombination.
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Test your knowledge about the lymphoid organs, their structure, and function in the immune response with this quiz covering Lesson 16 material.
