Podcast
Questions and Answers
Which factor deactivates liver phosphorylase enzyme?
Which factor deactivates liver phosphorylase enzyme?
What effect do hormones that increase cAMP levels have on the activation of glycogen phosphorylase?
What effect do hormones that increase cAMP levels have on the activation of glycogen phosphorylase?
How does insulin affect the activity of phosphoprotein phosphatase in relation to phosphorylase?
How does insulin affect the activity of phosphoprotein phosphatase in relation to phosphorylase?
Under what conditions does glucagon stimulate liver glycogen breakdown?
Under what conditions does glucagon stimulate liver glycogen breakdown?
Signup and view all the answers
Which hormone enhances glycogen breakdown in both muscle and liver for muscle contraction?
Which hormone enhances glycogen breakdown in both muscle and liver for muscle contraction?
Signup and view all the answers
Which process dominates in the liver during fasting?
Which process dominates in the liver during fasting?
Signup and view all the answers
What is the effect of high concentrations of ATP on muscle phosphorylase activity?
What is the effect of high concentrations of ATP on muscle phosphorylase activity?
Signup and view all the answers
Which hormone activates phosphorylase a in skeletal muscle?
Which hormone activates phosphorylase a in skeletal muscle?
Signup and view all the answers
What is the primary function of muscle phosphorylase in its 'a' form?
What is the primary function of muscle phosphorylase in its 'a' form?
Signup and view all the answers
Which compound is converted to glucose 6-phosphate in skeletal muscle?
Which compound is converted to glucose 6-phosphate in skeletal muscle?
Signup and view all the answers
In skeletal muscle, what regulates glycogen degradation in response to ATP needs?
In skeletal muscle, what regulates glycogen degradation in response to ATP needs?
Signup and view all the answers
Which molecule activates glycogen phosphorylase in the glucagon/epinephrine signaling pathway?
Which molecule activates glycogen phosphorylase in the glucagon/epinephrine signaling pathway?
Signup and view all the answers
In resting muscle, which form is predominantly inactive?
In resting muscle, which form is predominantly inactive?
Signup and view all the answers
What is the end product generated by glucose-6-phosphate entering the glycolytic pathway?
What is the end product generated by glucose-6-phosphate entering the glycolytic pathway?
Signup and view all the answers
Which molecule acts as a feedback inhibitor of glycogen phosphorylase?
Which molecule acts as a feedback inhibitor of glycogen phosphorylase?
Signup and view all the answers
What provides a direct and rapid means of stimulating glycogen degradation during muscle contraction?
What provides a direct and rapid means of stimulating glycogen degradation during muscle contraction?
Signup and view all the answers
Glycogen phosphorylase generates which molecule that is isomerized into glucose-6-phosphate?
Glycogen phosphorylase generates which molecule that is isomerized into glucose-6-phosphate?
Signup and view all the answers
How does insulin stimulate glycogen synthesis?
How does insulin stimulate glycogen synthesis?
Signup and view all the answers
What is the role of Protein Phosphatase 1 (PP1) in glycogen metabolism?
What is the role of Protein Phosphatase 1 (PP1) in glycogen metabolism?
Signup and view all the answers
How do myocytes contribute to lowering blood glucose in response to insulin?
How do myocytes contribute to lowering blood glucose in response to insulin?
Signup and view all the answers
What effect does elevated insulin have on glycogen synthesis in myocytes?
What effect does elevated insulin have on glycogen synthesis in myocytes?
Signup and view all the answers
What is the consequence of removing phosphoryl groups from glycogen synthase b by PP1?
What is the consequence of removing phosphoryl groups from glycogen synthase b by PP1?
Signup and view all the answers
How are cAMP cascades involved in regulating glycogen metabolism?
How are cAMP cascades involved in regulating glycogen metabolism?
Signup and view all the answers
What effect does glucagon have on muscle glycogen levels?
What effect does glucagon have on muscle glycogen levels?
Signup and view all the answers
What is the role of AMP in muscle glycogen phosphorylase activation?
What is the role of AMP in muscle glycogen phosphorylase activation?
Signup and view all the answers
From where do the effects of Ca in muscle primarily result?
From where do the effects of Ca in muscle primarily result?
Signup and view all the answers
How does epinephrine-stimulated phosphorylation affect skeletal muscle glycogen?
How does epinephrine-stimulated phosphorylation affect skeletal muscle glycogen?
Signup and view all the answers
What role does covalent modification play in the regulation of glycogen synthase?
What role does covalent modification play in the regulation of glycogen synthase?
Signup and view all the answers
How is glycogen synthase regulated by ATP and glucose-6-P?
How is glycogen synthase regulated by ATP and glucose-6-P?
Signup and view all the answers