Lipoprotein Structure and Composition

Polar lipid surface layer:

• Phospholipids
• Cholesterol
• Apoprotein

• Non-polar lipid core:

• TG
• Cholesterol ester

CM: transport of exogenous TG

• VLDL: Transport of endogenous TG
• IDL: Precursor of LDL
• LDL: Cholesterol transport to peripheral cells
• HDL: Reverse cholesterol transport

• Total cholesterol
• TG
• LDL cholesterol
• HDL Cholesterol
• Lp
• Apo B-100
• Apo B-48
• VLDL

<ul> <li>Blood is collected after 12 to 14 hours of fasting</li> <li>Maintain a normal diet for two weeks before blood collection</li> <li>Do not drink alcohol in the evening before the collecting day ( Even between 12-14h of fasting )</li> <li>For people with MI or Stroke: blood can be collected within 24 h or after 3 months</li> </ul> Signup and view all the answers

<ul> <li>Look at the serum that shows that it contains Chylomicron or VLDL, which is rich in TG.</li> </ul> Signup and view all the answers

<ul> <li>Hyperlipidemia can cause complications with uncontrolled type 1 and 2 diabetes and this is due to a combination of decreased lipoprotein lipase activity and increased liver TG synthesis. It can exacerbate ( ធន់ធរ ) coexisting familial hyperlipidemia.</li> </ul> Signup and view all the answers

<ul> <li>Serum cholesterol: 8 mmol / L ( 306 mg/dL )</li> <li>SerumTG:11mmol/L(974mg/dL)</li> </ul> <ul> <li>The patient was treated with insulin injection. His glucose level dropped rapidly and he was able to regain his stability by injecting insulin accordingly.</li> <li>After one week:</li> </ul> <ul> <li>Serum cholesterol: 8.0 mmol / L</li> <li>Serum TG: 11 mmol / L</li> </ul> <ul> <li>Diabetes well controlled:</li> </ul> <ul> <li>Cholesterol level: 6.0 mmol / L</li> <li>TG:5.3mmol/L</li> </ul> Signup and view all the answers