Layers of the Skin and Benign Neoplasms Quiz
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Questions and Answers

Which gene mutation is the most common in MTS Sweat Gland Tumors?

  • MSH2 (correct)
  • Lynch syndrome
  • CYLD
  • MTS

What is the most common type of differentiation in MTS Sweat Gland Tumors?

  • Glandular differentiation
  • Eccrine lesions (correct)
  • Ductal differentiation
  • Apocrine lesions

Which type of benign neoplasm is described as sometimes red and scaly?

  • Syringoma
  • Hidroacanthoma simplex
  • Cylindroma
  • Poroma (correct)

What is the characteristic pattern of arrangement seen in Cylindroma histology?

<p>&quot;Jigsaw puzzle&quot; pattern (A)</p> Signup and view all the answers

Which gene mutation is associated with the hereditary form of cylindroma, known as "turban tumor"?

<p>CYLD (A)</p> Signup and view all the answers

Which lesion is described as a small dermal collection of epithelial tubules, some with a "tadpole" shape?

<p>Syringoma (C)</p> Signup and view all the answers

What part of the hair follicle unit extends from the epidermal surface to the opening?

<p>Infundibulum (deep) (B)</p> Signup and view all the answers

Which syndrome is associated with multiple epidermal cysts, benign osteomas, and intestinal fibromatoses?

<p>Gardner syndrome (B)</p> Signup and view all the answers

What is the microscopic feature of a sebaceous adenoma?

<p>Vacuolated, bubbly, mature sebocytes (A)</p> Signup and view all the answers

Which gene mutation is responsible for Muir-Torre syndrome?

<p>MSH2 mismatch repair gene (D)</p> Signup and view all the answers

Which tissue is NOT present in the cyst wall of an epidermal cyst?

<p>Stratified squamous epithelium (D)</p> Signup and view all the answers

What is the characteristic feature of a central punctum in an epidermal cyst?

<p>Plugged with keratin debris (D)</p> Signup and view all the answers

Which benign skin adnexal lesion is associated with Muir–Torre syndrome?

<p>Sebaceous tumors (D)</p> Signup and view all the answers

What is the characteristic association of Gardner syndrome with colon cancer?

<p>Screen for colon cancer when cysts are unusual in number or location (D)</p> Signup and view all the answers

Which syndrome is a variant of hereditary nonpolyposis colorectal cancer syndrome and is associated with sebaceous adenomas?

<p>Muir-Torre syndrome (D)</p> Signup and view all the answers

What does the presence of multiple epidermal cysts indicate in a patient?

<p>Association with Gardner syndrome (B)</p> Signup and view all the answers

Which layer of the skin is responsible for providing a waterproof barrier?

<p>Epidermis (B)</p> Signup and view all the answers

What is the most common benign epithelial tumor?

<p>Seborrheic Keratosis (D)</p> Signup and view all the answers

What is a characteristic feature of Seborrheic Keratosis?

<p>Variable color from tan to black (D)</p> Signup and view all the answers

Which condition is commonly associated with metabolic syndrome?

<p>Acrochordon (Skin Tag) (D)</p> Signup and view all the answers

What is the characteristic histological composition of Acrochordon (Skin Tag)?

<p>Central core of loose collagen with increased blood vessels (D)</p> Signup and view all the answers

Which layer of the skin is characterized by connective tissue, hair follicles, and sweat glands?

<p>Dermis (B)</p> Signup and view all the answers

What does the 'Leser-Trelat Sign' refer to?

<p>&quot;Horn pseudocysts&quot; (B)</p> Signup and view all the answers

What is the primary characteristic of Dermatosis Papulosa Nigra?

<p>&quot;Stuck on&quot; appearance on the skin surface (C)</p> Signup and view all the answers

What is the role of Melanocytes in the skin?

<p>Produce melanin and determine skin color (D)</p> Signup and view all the answers

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