Laboratory Animal Handling in Drug Discovery

Scruffing the skin on the neck of the mouse is done to prevent it from turning its tail and escaping.

When administering a drug intraperitoneally, aspirating the needle is crucial to ensure it is inside the bladder.

When preparing for an intravenous injection, warming the tail is important to dilate the vessels.

The bevel of the needle during an intravenous injection should be faced downwards to penetrate the tail vein properly.

If resistance is felt during injection of a solution in an intravenous procedure, it indicates that the solution has been properly administered.