Animal Studies in Drug Discovery Process

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How should you restrain a mouse for subcutaneous administration of a drug?

Pinch the skin at the back of the neck with your thumb and forefinger.

What should you do if the mouse coughs or chokes during gavage administration?

Stop the administration immediately as it may indicate that the needle has entered the lungs.

How should you position the mouse for intraperitoneal drug administration?

Hold the mouse in a supine position and slightly tilt the head backward.

What is the recommended angle for inserting the needle during intraperitoneal administration?

<p>Around a 10-degree angle between the needle and the abdominal surface.</p> Signup and view all the answers

How should you prepare the mouse for intravenous administration?

<p>Warm the tail with a warm towel or a lamp to dilate the vessels.</p> Signup and view all the answers

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