Kidney Disease: Symptoms, Management and Transplants
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Questions and Answers

A patient with kidney disease presents with increased bleeding after a routine dental extraction. Which factor associated with kidney disease is MOST likely contributing to this complication?

  • Hypertension causing increased blood flow to the extraction site.
  • Corticosteroid treatment leading to decreased wound healing.
  • Underlying disease affecting platelet function and coagulation. (correct)
  • Impaired drug excretion leading to prolonged effects of local anesthetics.

A kidney disease patient on cyclosporine develops significant gingival overgrowth. What is the MOST appropriate initial management strategy?

  • Improve the patient's oral hygiene and consider professional mechanical plaque removal. (correct)
  • Prescribe a course of broad-spectrum antibiotics to reduce inflammation.
  • Discontinue cyclosporine immediately and switch to an alternative immunosuppressant.
  • Immediately refer the patient for surgical excision of the overgrown tissue.

A pediatric kidney disease patient exhibits delayed tooth eruption and enamel hypoplasia. Which underlying factor related to their condition is MOST likely responsible for these dental findings?

  • The impact of kidney disease on growth and development. (correct)
  • Increased susceptibility to viral infections like Herpes Simplex.
  • Diet leading to nutritional deficiencies.
  • Hypertension altering enamel formation.

A patient with kidney disease complains of persistent dry mouth and a metallic taste. Which of the following represents the MOST likely cause of these symptoms?

<p>Underlying disease and altered saliva composition. (B)</p> Signup and view all the answers

A kidney transplant recipient on immunosuppressants presents with a suspicious lesion on their lip. Which of the following malignancies should be of GREATEST concern?

<p>Squamous cell carcinoma (A)</p> Signup and view all the answers

A patient with chronic kidney disease reports experiencing itchy skin, what physiological process is most likely contributing to this symptom?

<p>Accumulation of urea and other waste products due to impaired kidney function. (C)</p> Signup and view all the answers

Which dietary modification is MOST important for managing edema (swollen ankles, feet, or hands) in a patient newly diagnosed with kidney disease?

<p>Limiting sodium intake to reduce water retention. (C)</p> Signup and view all the answers

A patient undergoing haemodialysis for end-stage renal disease asks about their long-term prognosis. What information is MOST accurate based on the information provided?

<p>Over 70% of patients on haemodialysis survive at least 5 years, but complications can still occur. (D)</p> Signup and view all the answers

A patient who has undergone a kidney transplant is prescribed corticosteroids, azathioprine, and cyclosporine. What is the primary reason for administering these medications?

<p>To prevent rejection of the transplanted kidney by suppressing the immune system. (C)</p> Signup and view all the answers

A kidney transplant recipient develops a fever and cough one month after surgery. Considering their medication regimen, what is the MOST likely concern?

<p>An infection due to immunosuppression. (D)</p> Signup and view all the answers

Flashcards

Kidney Disease: Appetite & Weight

Reduced appetite and unintentional weight loss.

Kidney Disease: Swelling

Fluid retention causing swelling, especially in ankles, feet, or hands.

Kidney Disease: Urination

Increased urge to urinate, especially at night.

Kidney Dialysis

A treatment that filters the blood when kidneys can't, but does not prevent all complications.

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Post-Transplant Immunosuppression

Suppresses the immune system to prevent rejection of the transplanted kidney.

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Kidney disease & infections

Increased susceptibility to infections like Candida, Herpes Simplex, Zoster, Cytomegalovirus, and Epstein-Barr.

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Bleeding tendencies

May occur due to immunosuppressive treatment and can affect dental treatment planning.

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Impaired drug excretion

Can lead to prolonged effects and increased risk of adverse reactions.

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Hypertension

Common in kidney disease and impacts dental management.

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Dry mouth (xerostomia)

Can occur due to kidney disease, corticosteroid use, and diet restrictions.

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Study Notes

  • Kidney disease signs and symptoms include the following:
  • Weight loss and poor apppetite
  • Shortness of breath (dyspnoea)
  • Swollen ankles, feet or hands, due to water retention
  • Increased need to urinate, especially at night
  • Insomnia
  • Itchy skin
  • Blood in urine (haematuria)

General Management

  • General management for kidney disease includes the following:
  • Low protein diet
  • Potassium restriction
  • Salt or water control
  • Dialysis/transplant
  • Prevention of further renal damage
  • Dialysis can give a normal life to up to 20% of patients, but does not prevent all complications.
  • Over 70% of patients on haemodialysis survive at least 5 years.
  • A renal transplant may become necessary.

Renal Transplantations

  • A survival graft can be up to 90% at one year for renal transplantations, which is now common.
  • Patients need to be immunosuppressed after the transplant.
  • Common medications involved in kidney transplants are:
  • Corticosteroid
  • Azathioprine
  • Cyclosporine
  • After transplant patients may still deal with problems associated with renal failure.
  • After transplant the patient are susceptible to infection from immunosuppression.
  • Patients also require steroid cover.

Dental Relevance

  • Consider these conditions when providing dental treatment to patients with kidney disease:
  • Bleeding tendencies
  • Underlying disease
  • Impaired drug treatment
  • Infections with hepatitis B and other viruses
  • Hypertension
  • Bone lesions of the jaw
  • Corticosteroid or other immunosuppressive treatment
  • Diet
  • Patients can expect the following symptoms:
  • Candida infection
  • Herpes Simplex or Zoster
  • Lymphomas and to a less degree
  • Skin, lip and cervical cancer
  • Cytomegalovirus
  • Epstein-Barr
  • Virus infections
  • Kaposi's Sarcoma
  • Cyclosporine may cause gingival overgrowth

Clinical Dental Relevance

  • Patients can also experience conditions which include:
  • Dry mouth
  • Halitosis
  • Metallic taste
  • Salivary gland swelling
  • Stunted Growth
  • Delayed tooth eruption
  • Enamel hypoplasia

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Description

Explore signs and symptoms of kidney disease, including weight loss, shortness of breath and blood in urine. Learn about general management which includes diet, dialysis, and transplant options. Understand renal transplantation, survival rates, and immunosuppressive medications.

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