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Renal/Transplant: Common Kidney Diseases and Injuries

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Renal/Transplant: Common Kidney Diseases and Injuries

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Questions and Answers

What is the main function of loop diuretics?

Inhibit H20 reabsorption in the descending limb of the loop of Henle (correct)

Promote Ca reabsorption in the proximal tubule

Reduce K+ reabsorption in the collecting duct

Increase Na and Cl reabsorption in the ascending limb of the loop of Henle

Which drugs work specifically at the distal convoluted tubule?

Aldosterone antagonists

ADH inhibitors

Thiazide diuretics (correct)

Loop diuretics

What is the primary function of aldosterone at the collecting duct?

Inhibit Na and Cl reabsorption

Increase Na and H20 reabsorption (correct)

Decrease K+ reabsorption

Promote Ca reabsorption

How is chronic kidney disease (CKD) measured?

By the degree of albuminuria and GFR Signup and view all the answers

What is a key risk factor for drug-induced kidney disease?

Concurrent use of multiple nephrotoxic medications Signup and view all the answers

What is the normal range of serum creatinine (SCr)?

0.6-1.3 mg/dL Signup and view all the answers

Under what conditions do we use ACE inhibitors (ACE-i) or angiotensin receptor blockers (ARBs) as first-line agents to prevent progression of chronic kidney disease (CKD)?

When albuminuria is present Signup and view all the answers

What is the general rule for drug dose adjustment when creatinine clearance (CrCl) is less than or equal to 30 mL/min?

Check for dose adjustments or consider the drug contraindicated Signup and view all the answers

Which of the following drugs is contraindicated when creatinine clearance (CrCl) falls below 50 mL/min?

Tenofovir disoproxil fumarate (TDF) containing products Signup and view all the answers

In patients with kidney disease, which complication may arise due to increased phosphate levels in the blood?

Hyperphosphatemia Signup and view all the answers