Questions and Answers
What is the main function of loop diuretics?
Inhibit H20 reabsorption in the descending limb of the loop of Henle
Which drugs work specifically at the distal convoluted tubule?
Thiazide diuretics
What is the primary function of aldosterone at the collecting duct?
Increase Na and H20 reabsorption
How is chronic kidney disease (CKD) measured?
Signup and view all the answers
What is a key risk factor for drug-induced kidney disease?
Signup and view all the answers
What is the normal range of serum creatinine (SCr)?
Signup and view all the answers
Under what conditions do we use ACE inhibitors (ACE-i) or angiotensin receptor blockers (ARBs) as first-line agents to prevent progression of chronic kidney disease (CKD)?
Signup and view all the answers
What is the general rule for drug dose adjustment when creatinine clearance (CrCl) is less than or equal to 30 mL/min?
Signup and view all the answers
Which of the following drugs is contraindicated when creatinine clearance (CrCl) falls below 50 mL/min?
Signup and view all the answers
In patients with kidney disease, which complication may arise due to increased phosphate levels in the blood?
Signup and view all the answers
