Introduction to Toxicology Importance
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Questions and Answers

What is the cornerstone in all aspects of chemical safety?

  • Chemistry
  • Physics
  • Biology
  • Toxicology (correct)
  • According to toxicology, what is the key theme related to the dose and the poison?

  • Acute toxicity
  • Chronic toxicity
  • Dose–response relationship (correct)
  • Synergistic effects
  • What are toxins and where do they originate from?

  • Naturally occurring beneficial substances from the environment
  • Harmful chemicals produced by humans
  • Poisons originating from plants, microbial organisms, and venoms released by animals (correct)
  • Synthetically produced pharmaceuticals
  • What term is used for the unintended effects of prescription drugs?

    <p>Side effects</p> Signup and view all the answers

    What drug was originally developed to reduce blood pressure but gained approval for treating erectile dysfunction?

    <p>Sildenafil</p> Signup and view all the answers

    Apart from therapeutic effects, what are all other responses to prescription drugs referred to as?

    <p>Side effects</p> Signup and view all the answers

    Which term is used to describe the toxic effects of a chemical that can develop rapidly after a single exposure, such as hydrogen cyanide or nerve gases?

    <p>Immediate toxicity</p> Signup and view all the answers

    What is the term used to describe the toxic effects of chemicals that may take months or years to be recognized?

    <p>Delayed toxicity</p> Signup and view all the answers

    Which type of toxic response is largely dependent on the ability of an injured tissue to adapt, repair, and regenerate?

    <p>Reversible toxic effect</p> Signup and view all the answers

    In toxicology, what term is used to characterize the proximity between the site of chemical exposure and the site(s) of molecular action?

    <p>Local toxicity</p> Signup and view all the answers

    What term is used to define an allergic reaction or sensitization reaction when a prior exposure to a chemical is required to produce its subsequent toxic effect?

    <p>Hypersensitivity</p> Signup and view all the answers

    What term is used to describe the toxic effects of chemicals that are reversible depending on the ability of an injured tissue to adapt, repair, and regenerate?

    <p>Reversible toxic effect</p> Signup and view all the answers

    In response to a previous exposure to a chemical or a structurally similar one, what kind of reaction can occur due to the immune system's adverse response?

    <p>Allergic reactions</p> Signup and view all the answers

    What can be observed for chemicals like hydrogen cyanide or nerve gases, leading to rapid effects on the cardiovascular, respiratory, and neurological systems culminating in death within minutes?

    <p>Immediate toxicity</p> Signup and view all the answers

    For tissues such as the liver and gastrointestinal tract that have a high ability to regenerate, many injuries are:

    <p>Reversible</p> Signup and view all the answers

    What type of damage is largely irreversible due to the CNS's limited ability to divide and replace damaged neurons?

    <p>Irreversible toxic effect</p> Signup and view all the answers

    What is the definition of drug addiction according to the text?

    <p>Loss of behavioral control over drug-seeking and drug-taking</p> Signup and view all the answers

    Which type of drug use is associated with causing widespread adaptive changes in the brain, as mentioned in the text?

    <p>Drug abuse or harmful use</p> Signup and view all the answers

    What is the primary goal of current neurobiological research on addiction, as mentioned in the text?

    <p>To understand the neuropharmacological and neuroadaptive mechanisms within specific neurocircuits</p> Signup and view all the answers

    According to the WHO, what is the definition of drug misuse?

    <p>Taking more than the recommended dose or mistakenly taking the wrong medication</p> Signup and view all the answers

    What is the state characterized by repeated, periodic, or continuous administration of a drug resulting in harm to the individual?

    <p>Drug dependence</p> Signup and view all the answers

    Which type of drug use is defined as occasional, controlled, or social use, based on the text?

    <p>Occasional, controlled or social use</p> Signup and view all the answers

    Which drug class primarily acts through activation of the sympathetic nervous system?

    <p>Stimulants</p> Signup and view all the answers

    What is one of the most frequent examples of natural stimulants mentioned in the text?

    <p>Khat</p> Signup and view all the answers

    Which drug is associated with symptoms such as altered mental status, life-threatening situations like coma, and seizures?

    <p>Opioids</p> Signup and view all the answers

    What is a serious medical complication arising from drug abuse that manifests during abstinence from the drug?

    <p>Withdrawal syndrome</p> Signup and view all the answers

    What are the cardiovascular manifestations of drug abuse mentioned in the text?

    <p>Arrhythmias and organ ischemia</p> Signup and view all the answers

    Which drug class may be correlated with the incidence of crime and is mentioned to accompany psychological dependence?

    <p>Stimulants</p> Signup and view all the answers

    What is a key element of drug addiction mentioned in the text?

    <p>Neurobiological bases for acute drug reward</p> Signup and view all the answers

    What type of symptoms can range from headaches and altered mental status to life-threatening situations like coma and seizures due to drug abuse?

    <p>Central nervous system symptoms</p> Signup and view all the answers

    What type of illness may accompany psychological dependence on certain drugs according to the text?

    <p>Physical illness</p> Signup and view all the answers

    What may occur due to misuse of drugs, such as alterations in body temperature, electrolytes, and acid–base disturbances?

    <p>Metabolic effects</p> Signup and view all the answers

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