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Questions and Answers
What is the primary purpose of maceration in tincture preparation?
What is the primary purpose of maceration in tincture preparation?
Which of the following is an example of a tincture prepared by percolation?
Which of the following is an example of a tincture prepared by percolation?
What is the typical amount of Balledona leaf used to prepare 100 mL of Belladona tincture?
What is the typical amount of Balledona leaf used to prepare 100 mL of Belladona tincture?
What evaluation parameters are commonly used for tinctures?
What evaluation parameters are commonly used for tinctures?
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Which tincture is recognized for its anti-infective properties?
Which tincture is recognized for its anti-infective properties?
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What is the purpose of the alcohol in tinctures?
What is the purpose of the alcohol in tinctures?
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What is a common disadvantage of tinctures?
What is a common disadvantage of tinctures?
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What is the typical range of alcohol content in tinctures?
What is the typical range of alcohol content in tinctures?
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Which of the following is an example of a tincture used topically?
Which of the following is an example of a tincture used topically?
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What process is followed to ensure the proper preparation of tinctures?
What process is followed to ensure the proper preparation of tinctures?
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What additional solvent may be used in the preparation of tinctures aside from alcohol?
What additional solvent may be used in the preparation of tinctures aside from alcohol?
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Why are tinctures stored in light-resistant containers?
Why are tinctures stored in light-resistant containers?
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What is the primary reason a physician might prefer a single drug over a tincture?
What is the primary reason a physician might prefer a single drug over a tincture?
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Study Notes
Tincture Introduction
- Tinctures are alcoholic or hydroalcoholic solutions prepared from vegetable materials or chemical substances.
- Alcohol content ranges from 15% to 80% to prevent microbial growth and keep alcohol-soluble extractives in solution.
- Other solvents like glycerin can be used.
- Tinctures need to be tightly stoppered, protected from excessive temperatures and sunlight, and stored in light-resistant containers.
### Disadvantages of Tinctures
- Unpleasant taste.
- Physicians may prefer single drugs over plant-based preparations.
- High alcohol content.
### Topical Tincture Examples
-
Green Soap Tincture:
- Coconut and vegetable oil-based soap blend with 30% ethyl alcohol, glycerin, and 2% lavender oil.
- Used for skin cleaning after tattoos and piercings, cleaning surgical instruments.
- Soothes and softens skin, helps with moisture retention.
-
Compound Benzoin Tincture (CTB):
- Applied to skin before adhesive bandages to prevent allergy and extend adhesion time.
- Used in orthopedics to spray on skin before casting, protecting skin and reducing itching.
- Used as an oral mucosal protectant.
-
Iodine Tincture:
- An antiseptic, also known as weak iodine solution.
- Contains 2-7% elemental iodine, potassium iodide or sodium iodide, dissolved in a mixture of ethanol and water.
Tincture Variations
- Variations exist in methods of preparation, strengths of active constituents, alcohol content, and intended use.
Old Tincture Preparation Method
- Requires minimum 40% alcohol for extraction.
- Use a dark-colored bottle.
- Dried and powdered plant material is used.
- Standard ratio is 4 parts liquid to 1 part herb.
- Soak for 4 weeks in a cool, dark place.
- Filter the solution and transfer to a suitable container.
Tincture Preparation Methods
- Simple solution: Used for chemical substances like iodine, thimerosal, and nitromersol.
-
Extraction:
- Maceration: Simplest method, used for compound benzoin tinctures, sweet orange peel tincture, and tolu balsam tincture.
- Percolation: Used for belladonna tincture and vanilla tincture.
Tincture Strength
- No set strength for compound tinctures.
- Varies depending on the preparation.
- Generally, the amount of crude drugs per 100mL of tincture is:
- Potent drugs: Belladona leaf - 10g
- Non-potent drugs: Tolu balsam - 20g
- Undried fresh fruit peel: Sweet orange peel - 50g
Pharmaceutical Uses
- Flavoring: Vanilla, sweet orange peel, Tolu balsam.
- Medicinal: Iodine, Thimerosal, Nitromersol.
- Anti-infective: Compound Benzoin.
- Topical protectant: Green soap.
- Topical detergent: Belladona (anticholinergic).
Tincture Evaluation
Evaluated by:
- Relative density (or specific gravity)
- Total solid residue
- pH
- Moisture content
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Description
This quiz explores the foundational concepts of tinctures, including their composition, storage requirements, and common applications. It also discusses the disadvantages of tinctures and provides examples of topical tinctures, highlighting their uses and benefits. Test your knowledge of this essential topic in herbal preparations.