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Introduction to Thermodynamics: Energy Metabolism

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FatihSultanMehmet
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23 Questions

What type of energy is used by biologic systems to power living processes?

Chemical energy

Which law of thermodynamics states that the total energy of a system, including its surroundings, remains constant?

First law of thermodynamics

What does a negative ∆H value indicate in a chemical reaction?

The reaction is exothermic

What happens if ΔG is negative in a reaction?

The reaction proceeds spontaneously with loss of free energy

What term describes the extent of disorder or randomness of a system?

Entropy

When does a reaction become irreversible according to the text?

When ΔG is negative

What type of bond is broken during the hydrolysis of ATP to ADP and Pi or ATP to AMP and PPi?

Acid anhydride (phospho anhydride) bond

Which of the following is NOT considered a 'high-energy compound' in biochemistry?

Glucose

Which of the following is the first product in urea and pyrimidine synthesis?

PPi

Which type of phosphorylation occurs in glycolysis?

Substrate level phosphorylation

What is the role of phosphagens in the body?

All of the above

Which of the following compounds can regenerate ATP from ADP and Pi or ATP from AMP and PPi?

Acid anhydride (phospho anhydride) bond

What happens if ΔG is positive?

The reaction proceeds only if free energy can be gained

In what kind of system is ΔG zero?

System at equilibrium

What term is used for the breakdown or oxidation of fuel molecules?

Catabolism

Which type of reactions build up substances?

Anabolic reactions

What is the constituting feature of both catabolic and anabolic processes?

Metabolism

What is ATP composed of?

Adenosine and three phosphate groups

What is the major energy source in 100m runners?

Creatine phosphate

How long does it take for the stores of creatine phosphate to become depleted in runners?

30-50 seconds

What is the role of Adenylyl Kinase (Myokinase) in cells?

Maintains energy homeostasis by enabling the synthesis of ATP

What is the significance of AMP increasing in concentration when ATP becomes depleted?

To enhance the rate of catabolic reactions for ATP generation

Which enzyme catalyzes the group transfer potential in ADP for ATP synthesis?

Adenylyl Kinase (Myokinase)

Learn about energy metabolism in living organisms and how it relates to thermodynamics. Understand how biologic systems use chemical energy to power processes and adhere to the laws of thermodynamics. Contact Asst. Prof. Betül Özbek at [email protected] for more information on the course in 2023-2024.

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