Introduction to Pharmacology Quiz
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Questions and Answers

What is the term used for the name assigned to drugs by the WHO?

  • Proprietary name
  • Brand name
  • Generic name (correct)
  • Trade name
  • Which of the following is NOT a characteristic of veterinary medicines?

  • Active ingredient used as the primary term of reference
  • Exclusively available under brand names (correct)
  • Description in terms of physical characteristics
  • Grouping into classes based on structure and properties
  • What is the role of excipients in the formulation of medications?

  • To replace the active ingredient
  • To enhance the active ingredient's potency
  • To provide necessary nutrients
  • To aid in the formulation process and stability (correct)
  • What factors influence the process of medicine development?

    <p>The drivers of drug discovery and associated costs</p> Signup and view all the answers

    Which of these terms is synonymous with 'brand name' in the context of medicines?

    <p>Proprietary name</p> Signup and view all the answers

    What is the primary term of reference when describing a veterinary medicine?

    <p>Active ingredient</p> Signup and view all the answers

    What does the International Non-proprietary Name (INN) signify?

    <p>It identifies the active pharmaceutical ingredient.</p> Signup and view all the answers

    Which of the following correctly describes the grouping of medicines?

    <p>Grouped into classes of similar physicochemical characteristics.</p> Signup and view all the answers

    What is the IUPAC ID for the compound represented by the chemical formula C21H23NO5?

    <p>(5α,6α)-7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate</p> Signup and view all the answers

    What is a characteristic common to pharmacologically related substances?

    <p>They often have a similar stem in their generic name.</p> Signup and view all the answers

    What is the website provided for the Product Information Database?

    <p><a href="http://www.vmd.defra.gov.uk/ProductInformationDatabase/">www.vmd.defra.gov.uk/ProductInformationDatabase/</a></p> Signup and view all the answers

    Which of the following is a method used to classify medicines?

    <p>Based on their physicochemical properties</p> Signup and view all the answers

    Which name is considered the proprietary name in veterinary medicine?

    <p>Metacam</p> Signup and view all the answers

    What benefit does understanding drug classes provide in prescribing?

    <p>It allows predicting the effects of all drugs within that class</p> Signup and view all the answers

    What is one of the main roles of the prescribing framework?

    <p>To assess the patient and identify treatment options.</p> Signup and view all the answers

    What grouping is NOT mentioned as a basis for classifying drugs?

    <p>Brand name popularity</p> Signup and view all the answers

    What organization selects and publishes the International Non-proprietary Names (INN)?

    <p>World Health Organization (WHO)</p> Signup and view all the answers

    Which of the following drugs is classified under β-lactam antibiotics?

    <p>Amoxicillin</p> Signup and view all the answers

    What is a common mechanism of action for NSAIDs?

    <p>Inhibition of cyclooxygenase</p> Signup and view all the answers

    Which of the following is NOT a characteristic of drug classification based on clinical outcomes?

    <p>The duration of action</p> Signup and view all the answers

    Which of the following is a benefit of classifying drugs based on their structure and properties?

    <p>It helps in memorizing drugs</p> Signup and view all the answers

    What role do excipients play in medication formulations?

    <p>They help make the medication suitable for administration.</p> Signup and view all the answers

    What is the typical cost to bring a new drug for human use to market?

    <p>$2 billion</p> Signup and view all the answers

    How long are companies protected from generic competition after developing a new drug?

    <p>20 years</p> Signup and view all the answers

    Which document describes the properties and uses of a medicinal product?

    <p>Summary of Product Characteristics</p> Signup and view all the answers

    What is the primary focus of the process during drug development?

    <p>To achieve effective and safe medications</p> Signup and view all the answers

    What is the main focus of pharmacology?

    <p>The mechanisms and actions of drugs</p> Signup and view all the answers

    What is the purpose of pre-reading before the lecture?

    <p>To refresh knowledge on key topics</p> Signup and view all the answers

    What distinguishes therapeutics from pharmacology?

    <p>Pharmacology examines drug mechanisms, while therapeutics focuses on the treatment of diseases.</p> Signup and view all the answers

    What is one expected outcome after attending a lecture?

    <p>Improved prescribing skills and drug knowledge</p> Signup and view all the answers

    How is a drug defined?

    <p>A substance that produces a biological effect for an intended purpose</p> Signup and view all the answers

    Which of the following is NOT a part of the pre-lecture preparation?

    <p>Choosing a group project topic</p> Signup and view all the answers

    What activity is specifically mentioned as part of the after-lecture process?

    <p>Participating in exercises to develop prescribing skills</p> Signup and view all the answers

    In which setting are lectures expected to be attended for maximum benefit?

    <p>In-person</p> Signup and view all the answers

    Which of the following anti-epileptic drugs is known for its effectiveness in treating seizures in dogs?

    <p>Phenobarbital</p> Signup and view all the answers

    What is a primary characteristic of a suspension in veterinary medicine?

    <p>Contains suspended particles in a liquid</p> Signup and view all the answers

    Which excipient is specifically used as an antioxidant in formulations?

    <p>Butylhydroxytoluene</p> Signup and view all the answers

    What role does stearic acid play in medication formulations?

    <p>Emulsifying agent</p> Signup and view all the answers

    Which physical form of medication is typically used for delivering drugs directly into the bloodstream?

    <p>IV infusions</p> Signup and view all the answers

    What is one key driver in the discovery and development of new medicines?

    <p>Public demand for alternative treatments</p> Signup and view all the answers

    What is a characteristic of a tablet medication?

    <p>Is a solid dosage form</p> Signup and view all the answers

    Which excipient serves primarily as a flavouring agent in veterinary medicine?

    <p>Poultry liver powder</p> Signup and view all the answers

    Study Notes

    Introduction to Pharmacology

    • The subject is challenging for students.
    • Pre-reading is important; read a maximum of 4 pages before each lecture.
    • In-person lectures are crucial for optimal learning of the subject material.
    • Lectures are recorded.
    • Exercises in class will help develop prescribing skills and drug knowledge.
    • Short quizzes are used to assess student understanding of learning objectives.

    Resources

    • Students should use Rang & Dale's Pharmacology (10th ed.) and Pharmacology (5th ed.) textbooks.
    • Veterinary Pharmacology and Therapeutics (10th ed.) is another recommended text.

    Pharmacology vs Therapeutics

    • Pharmacology is the study of drug mechanisms and actions.
    • Therapeutics is the application of drugs to treat diseases.

    What is a Drug?

    • A drug is a substance that, when introduced into the body, produces a biological effect for an intended purpose.

    Learning Objectives (Page 6)

    • Understand various ways to name medications.
    • Identify and use the active ingredient as the primary reference term.
    • Understand groupings of medications based on structure and properties.
    • Describe veterinary medicines based on physical characteristics.
    • Understand the role of excipients in medication formulations.
    • Understand the principles of medication development, including drivers, costs, and timescales.

    Learning Objective 1 (Names of Medications)

    • Drugs are known by their International Non-proprietary Name (INN) or generic name.
    • These names are assigned by the World Health Organization (WHO).
    • Drug companies may also use proprietary or brand names for a product.

    Learning Objective 2 (Active Ingredients)

    • The active ingredient in a medication is its generic name.
    • This reference name should always be used in veterinary medicine exams.

    Learning Objective 3 (Drug Classification)

    • Medications can be categorized based on: physicochemical properties, target binding (pharmacological action), or clinical outcomes (pharmacotherapeutic action).
    • Classifying drugs helps in predicting their effects.
    • Example: β-lactam antibiotics, cyclooxygenase inhibitors, and anti-epileptic drugs.

    Learning Objective 4 (Physical Characteristics)

    • Physical characteristics are crucial in describing veterinary medicines, such as tablets, capsules, injections, spot-ons, suspensions, IV infusions, eye drops, drenches, and creams/ointments.

    Learning Objective 5 (Excipients)

    • Excipients are essential components of drug formulations to aid delivery.
    • Excipients may include fillers, binders, disintegrants, lubricants, colorants, flavourings, and preservatives.

    Learning Objective 6 (Drug Development)

    • Drug development is high-risk and expensive.
    • A new human drug can cost $2 billion and take 10-15 years to reach the market.
    • Companies benefit from patent protection for around 20 years.

    Prescribing Framework

    • This cyclical process outlines the prescribing framework
    • Steps include:
      • Assess the patient
      • Identify effective treatment options
      • Present options to the client
      • Provide supporting information
      • Prescribe the correct medicine

    Prescribing Skills

    • Deciding on the correct drug, dose, route, frequency of medication
    • Identifying components that could be unsuitable
    • Deciding on the most appropriate treatment
    • Providing crucial information to the client
    • Calculating and verifying accurate doses
    • Identifying possible adverse drug reactions
    • Monitoring and interpreting results of investigations

    Prescribing Information (Veterinary Medicines Directorate)

    • This database contains summaries of product characteristics for veterinary medicines.

    Additional Key Points

    • Summary of Product Characteristics (UK and EU)
    • Prescribing Information (USA)
    • These documents feature detailed information about drugs; including how to use them and precautions to take.

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    Quiz Team

    Description

    This quiz assesses your understanding of basic pharmacology concepts, including drug mechanisms, therapeutic applications, and medication naming. It is designed to complement the readings from 'Rang & Dale's Pharmacology' and other key texts. Prepare for both lectures and practical applications in this essential field of study.

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