Introduction to Immunology
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Questions and Answers

What is the primary focus of the Immunology session guided by Ms. Lazarou?

  • To conduct experiments on immune reactions
  • To develop self-directed learning on immunology (correct)
  • To prepare for practical applications in dental therapy
  • To memorize all terminology related to immunology

Which of the following is NOT a goal of the session on immunology?

  • Describe various immune system disorders (correct)
  • Define immunology and relevant terminology
  • Identify the components of innate and adaptive immunity
  • Differentiate between non-specific and adaptive immunity

Which method of note-taking is encouraged for building Immunology notes?

  • Linear notes only
  • Audio recordings only
  • Spider diagrams and memory maps (correct)
  • Only summarizing key points

Which type of immunity is characterized as non-specific?

<p>Innate immunity (B)</p> Signup and view all the answers

What is the timeline for completing the 'Introduction to Immunology' workbook?

<p>Prior to the next learning session (B)</p> Signup and view all the answers

What is one component that must be recognized in the immune system?

<p>Immune system organs and tissues (B)</p> Signup and view all the answers

Which of the following describes adaptive immunity?

<p>It is specific and develops over time. (A)</p> Signup and view all the answers

What type of assessment follows the completion of the immunology workbook?

<p>A summative e-assessment (B)</p> Signup and view all the answers

What are the primary types of immune systems described?

<p>Innate and adaptive (A)</p> Signup and view all the answers

Which of the following correctly describes a characteristic of the innate immune system?

<p>It responds immediately to infections. (B)</p> Signup and view all the answers

What role do oral cavity barriers play in the immune response?

<p>They prevent pathogens from entering the body. (B)</p> Signup and view all the answers

What is a consequence of chronic inflammation linked to oral health?

<p>Clogged arteries due to immune activation. (D)</p> Signup and view all the answers

Which of the following is a non-specific immune response mechanism?

<p>Phagocytosis by macrophages. (A)</p> Signup and view all the answers

Which condition is associated with increased systemic inflammation linked to oral diseases?

<p>Diabetes. (B)</p> Signup and view all the answers

What contributes to the pathogenesis of periodontal disease?

<p>Activation of immune cells by plaque bacteria. (D)</p> Signup and view all the answers

Which of the following describes a function of the adaptive immune system?

<p>Memory formation for future infections (B)</p> Signup and view all the answers

What is one of the primary roles of barriers in the innate immune system?

<p>Preventing pathogen entry (A)</p> Signup and view all the answers

Which condition is linked to chronic inflammatory responses associated with oral health?

<p>Heart disease (A)</p> Signup and view all the answers

What component is crucial in the collaboration between oral health and systemic inflammation?

<p>Plaque bacteria (B)</p> Signup and view all the answers

Which statement accurately describes a significant feature of the adaptive immune system?

<p>It creates a memory of specific pathogens. (A)</p> Signup and view all the answers

Which of the following is considered an oral cavity barrier in the immune response?

<p>Mucosal membranes (A)</p> Signup and view all the answers

What distinguishes adaptive immunity from innate immunity?

<p>Specificity to particular antigens (B)</p> Signup and view all the answers

Which of the following best explains the impact of hyperglycemia on inflammation?

<p>It increases cellular apoptosis. (D)</p> Signup and view all the answers

What is one example of an oral disease associated with immune response dysfunction?

<p>Gingivitis (A)</p> Signup and view all the answers

What is the ultimate aim of the subject discussed in this session?

<p>To develop knowledge in the study of immunology (A)</p> Signup and view all the answers

What is one of the intended learning outcomes for this session?

<p>Differentiate between innate and adaptive immunity (B)</p> Signup and view all the answers

Which task involves reviewing an article on antibody-mediated and cell-mediated immunity?

<p>Student Learning Task 1 (D)</p> Signup and view all the answers

Which of the following represents a component of the immune system that students need to identify?

<p>Lymph nodes (C)</p> Signup and view all the answers

In what way are students encouraged to make notes during the immunology session?

<p>By using pictures and tables in addition to written notes (A)</p> Signup and view all the answers

What is the purpose of the 'Introduction to Immunology' workbook?

<p>To provide a structured way to consolidate immunology knowledge (D)</p> Signup and view all the answers

Which statement best describes adaptive immunity?

<p>It involves a specific response developed after exposure to an antigen. (B)</p> Signup and view all the answers

What type of knowledge will students likely NOT encounter in this session?

<p>Psychological effects of immune system responses (B)</p> Signup and view all the answers

Flashcards

Immunology Definition

The study of the immune system and its workings.

Natural Defence Systems

The body's inbuilt ways to defend against pathogens.

Non-specific (Innate) Immunity

The body's general, quick response to any invader.

Adaptive (Acquired) Immunity

The body's specialized response to specific pathogens.

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Immune System Organs

Structures where immune cells develop, mature, and function.

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Antibody-mediated Immunity

Part of adaptive immunity that uses antibodies to fight pathogens.

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Cell-mediated Immunity

Part of adaptive immunity that uses specialized cells to destroy pathogens.

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Immune System Cells

Diverse cells involved in both innate and adaptive immunity.

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Oral Cavity Stress

The mouth's soft and hard tissues constantly experience pressure from external forces and foreign substances.

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Dental Caries

A common oral disease caused by bacterial decay of tooth enamel.

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Periodontitis

An inflammatory disease affecting the gums and supporting bone structure of teeth.

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Inflammation and Oral Diseases

Chronic inflammatory conditions can be linked to oral diseases, impacting overall health.

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Plaque Bacteria and Heart Disease

Plaque bacteria can trigger immune responses contributing to clogged arteries and heart disease.

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Diabetes and Periodontal Disease

Diabetes and periodontal disease are linked by shared inflammatory processes.

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Hyperglycaemia and Immune System

High blood sugar (hyperglycaemia) can worsen inflammation, oxidative stress, and cell death.

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Oral Cavity Immunity Importance

Understanding the immune system in the mouth is crucial for preventing and treating oral diseases and their systemic health implications.

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Immunology

The study of the body's defense mechanisms against diseases caused by pathogens (like bacteria, viruses, and fungi).

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Organs of the Immune System

Structures where immune cells are produced, mature, and function, like the bone marrow, spleen, and lymph nodes.

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Cells of the Immune System

Different types of cells like lymphocytes (B cells and T cells), macrophages, neutrophils, and mast cells that work together to fight infections.

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What are the two main types of immunity?

The two main types of immunity are innate (nonspecific) immunity and adaptive (specific) immunity. Innate immunity is the body's first line of defense against pathogens, and it's always active. Adaptive immunity is more specific and develops over time as you're exposed to new pathogens.

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What are examples of innate immune barriers?

Innate immune barriers are the body's first line of defense against pathogens and include physical barriers like skin and mucous membranes, chemical barriers like stomach acid and saliva, and cellular defenses like phagocytes.

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What are the key components of the adaptive immune system?

The adaptive immune system has two main arms: cell-mediated immunity and antibody-mediated immunity. Cell-mediated immunity involves T cells directly attacking infected cells, while antibody-mediated immunity relies on antibodies produced by B cells to neutralize pathogens.

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What is the role of oral cavity immunity?

The oral cavity's immune system protects against pathogens that can cause dental caries, periodontitis, and other infections. It's also linked to systemic health because inflammation in the mouth can contribute to other conditions like heart disease and diabetes.

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Why is plaque bacteria a concern?

Plaque bacteria can trigger inflammation in the gums and contribute to the development of periodontal disease. They can also release substances that trigger inflammation in blood vessels, increasing the risk of heart disease.

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How does diabetes impact the immune system?

High blood sugar (hyperglycemia) in diabetes can worsen inflammation and oxidative stress, making individuals more susceptible to infections and potentially contributing to complications.

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Explain the connection between oral diseases and other chronic conditions.

Chronic inflammation is often linked to both oral diseases and other chronic conditions like heart disease and diabetes. Inflammation in the mouth can release substances that travel through the body, contributing to inflammation and worsening these conditions.

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What are the main types of oral diseases?

The main types of oral diseases include dental caries (tooth decay) and periodontitis (gum disease). Both are caused by bacterial infections and can lead to significant oral health problems.

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Study Notes

Introduction to Immunology

  • Tutor: Ms P Lazarou
  • Module: Biomedical Sciences
  • Course: Dental Therapy/Dental hygiene
  • Learning Aims: To apply biomedical principles, behavioural and materials sciences to dental therapy and hygiene
  • Learning Outcomes
    • Define immunology and associated terminology
    • Describe natural body defense systems
    • Identify components & functions of innate & adaptive immune systems
    • Differentiate between innate & adaptive immunity
    • List immune system cells (innate and adaptive)

Student Learning Guidelines

  • Self-directed learning: Sessions are designed for independent completion of tasks
  • PowerPoint slides: Each slide should be carefully reviewed, and instructions followed
  • Supplemental resources: Links to documents and research articles are provided to enhance learning
  • Note-taking methods: Encourage the use of various note-taking methods (spider diagrams, images, tables) to create personal Immunology notes.
  • Preparation for next session: Complete and review notes before the following session to consolidate knowledge.

GDC Learning Outcomes

  • Subject aims to apply biomedical, behavioral, and material sciences fundamentals to dental therapy and hygiene practices
  • Development of immunology knowledge is a core component

Intended Learning Outcomes (Session)

  • Defining immunology: Understanding the field and appropriate terminology
  • Natural defense systems: Describing the body's natural defenses
  • Immune System (components & functions): Non-specific (Innate) and Specific(Adaptive or Acquired)
  • Differentiating immune types: Distinguishing between innate and adaptive immunity
  • Immune cells: Identifying innate and adaptive immune cell types.

Assessment

  • Formative: Complete an "Introduction to Immunology Workbook".
  • Summative: Biomedical Sciences Assessment

Student Learning Task 1

  • Article: Read an article titled "An introduction to immunology and immunopathology" (10 of 14 sections)
  • Source: From Moodle, by Jean S. Marshall, Richard Warrington, Wade Watson, and Harold L. Kim (2018) on biomedcentral.com
  • Time allocation: 15 minutes

Student Learning Task 2

  • Task: Research and create notes/diagrams/maps on organs and tissues of the immune system
  • Resources: Online articles such as "What are the organs of the immune system?", "Components of the Immune System", and "Bitesize Immunology"
  • Time allocation: 15 minutes

Student Learning Task 3

  • Task: Notate and review immunology terminology to complete Worksheet 1
  • Material: Complete Worksheet 1 of the Immunology Workbook.
  • Time allocation: 20 minutes
  • Repeat: Continue adding terms

Student Learning Task 4

  • Task: Review and describe cell functions in the innate and adaptive immune systems
  • Material: Complete Worksheet 2 in the Immunology Workbook.
  • Time allocation: 15 minutes

Student Learning Task 5

  • Task: Outline the differences between innate and adaptive immune systems
  • Note-taking: Fill in a table in the workbook for these differences
  • Method: Drag and drop answers
  • Time allocation: 10 minutes

Student Learning Task 6

  • Task: Describe the barriers of the innate immune system, give mechanisms for example
  • Focus: Mechanisms in the oral cavity
  • Material: Complete Worksheet 3 of the Immunology Workbook
  • Time allocation: 15 minutes

Immunity in the Oral Cavity

  • Tissue stress: Soft and hard oral tissues subjected to constant stress from foreign matter and external forces
  • Oral diseases:
    • Dental caries
    • Periodontitis
  • Significance: links between chronic inflammation and oral diseases, such as the activation of immune cells by plaque bacteria also affecting arteries, and contributing to both periodontal disease and diabetes.

Why Immunity in the Oral Cavity Matters

  • Chronic inflammation relation: Immune system responses linked to both periodontal disease and diabetes.
  • Systemic markers of inflammation: Elevated systemic inflammation markers in diabetes (Type 1 and 2), affecting microvascular and macrovascular areas
  • Hyperglycaemia: This can increase inflammation, oxidative stress, and cell death

Immunity and Diseases

  • Systemic disease links: Diseases like Oral candidiasis, Sjögren's syndrome, and Pemphigus vulgaris, related to systemic diseases, that affect the oral cavity.
  • Immunological Assessment: These topics will be further assessed in Session 3

References/Resources

  • Article: "An introduction to immunology and immunopathology" by Richard Warrington et. al. (2011)
  • Other resources: Various websites including: ResearchGate, InformedHealth.org (NCBI Bookshelf), Healio.com, British Society for Immunology, and immunology.org.

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Description

Explore the fundamentals of immunology in this quiz designed for Biomedical Sciences within Dental Therapy. You will learn to define key terminology, describe the body's natural defense systems, and distinguish between innate and adaptive immunity. Assess your understanding of immune system components and their functions.

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