Introduction to Immunology DTH23 PDF

Introduction to immunology Tutor: Ms P Lazarou Module: Biomedical Sciences 2 Student Learning guidelines The premise of this session is for you to complete the tasks in a self-directed way Work through each PowerPoint slide and follow the instructions There are links t...

Introduction to immunology Tutor: Ms P Lazarou Module: Biomedical Sciences 2 Student Learning guidelines The premise of this session is for you to complete the tasks in a self-directed way Work through each PowerPoint slide and follow the instructions There are links to documents and research articles which will enable you to gain knowledge of this subject and to complete the tasks as you proceed You are encouraged to use various methods of notetaking such as spider diagrams/pictures/tables to help you build up your Immunology notes It is important that you complete and have your notes in preparation for the next session in order that knowledge of the subject matter is consolidated. GDC Learning Outcomes The aim of this subject is to apply to the practice of dental therapy and dental hygiene principles that derive from the biomedical, behavioural and materials sciences. To develop knowledge in the study of immunology. GDC 1.1 Intended learning outcomes By the end of the session you will be able to: Define immunology and recognise the terminology associated with it Describe the natural defence systems of the body Identify the components and functions of the non-specific (innate) and adaptive (acquired) immune systems Differentiate between non-specific (innate) and adaptive (acquired) immunity Recognise and list the cells of the non-specific immune system and the adaptive immune system Assessment Formative Summative Complete ‘Introduction to Biomedical Sciences Immunology’ Workbook Eassessment Student Learning Task 1 Download the following article from Moodle and read up to (10 of 14) ‘Antibody-mediated vs. cell-mediated immunity’ An introduction to immunology and immunopathology Jean S. Marshall, Richard Warrington, Wade Watson and Harold L. Kim (2018) An introduction to immunology and immunopathology (biomedcentral.com) (15 minutes) Student Learning Task 2 Research and make own notes/spider diagram/memory map on the organs and tissues of the Immune System in the Immunology Workbook (suggested resources): What are the organs of the immune system? - InformedHealth.org - NCBI Bookshelf (nih.gov) https://www.immunology.org/public-information/bitesized-immunology https://www.healio.com/hematology-oncology/learn-immuno-oncology/the-immune-system/components-of-the- immune-system (15 minutes) Student Learning Task 3 Notate and review terminology associated with immunology* Complete Worksheet 1 in the Immunology Workbook (20 minutes) Continue to add to this when new terminology encountered * Student Learning Task 4 Review the cells of the non-specific and the adaptive immune system with a brief description of their functions. Worksheet 2 in Workbook: Fill in the blanks. (15 minutes) Student Learning Task 5 Outline the distinctions between the innate and the adaptive immune systems. Complete the table in the Workbook: drag and drop answers (10 minutes) Student Learning Task 6 Describe the barriers of the innate immune system. Give the mechanism for each example. Which barriers are associated with the oral cavity? Complete Worksheet 3 in the Workbook. (15 minutes) Immunity in the oral cavity Soft and hard tissues are constantly under stress from external forces/foreign matter Oral diseases/disorders: Dental caries Periodontitis Immunity in the oral cavity Why is it important? There are known to be links between chronic inflammatory conditions and oral diseases e.g. activation of immune cells by plaque bacteria may contribute to arteries becoming clogged with fatty substances, leading to heart disease Inflammation is a key feature of the pathogenesis of both periodontal disease and diabetes Diabetes (Type 1 and Type 2) is associated with elevated levels of systemic markers of inflammation contributing to microvascular and macrovascular complications. Hyperglycaemia can result in increased inflammation, oxidative stress and apoptosis (cell death) You will gain further knowledge in these subjects throughout your course. Immunity in the oral cavity Diseases secondary to systemic disease/autoimmune/acquired immunodeficiency: Oral candidiasis Sjögren’s syndrome Pemphigus vulgaris We will be looking further into these conditions in Immunology Session 3 References/resources  An introduction to immunology and immunopathology Richard Warrington1*, Wade Watson2 , Harold L Kim3,4, Francesca Romana Antonetti5 (2011) https://www.researchgate.net/publication/ 51875109_An_introduction_to_immunology_and_immunopathology  What are the organs of the immune system? - InformedHealth.org - NCBI Bookshelf (nih.gov)  Components of the Immune System (healio.com)  British Society for Immunology https://www.immunology.org/public-information/bitesized- immunology