Insulin Lispro Overview

Study Notes

Insulin Lispro Overview

Brand name: Humalog
Generic name: Insulin Lispro

Indications

Used for treating type 1 diabetes mellitus and type 2 diabetes mellitus when diet, exercise, and weight reduction alone are insufficient.

Dosing

Individualized dosage is crucial for effective treatment.
Offers a more rapid onset and shorter duration compared to human regular insulin.

Medication Strengths and Forms

Humalog available at a concentration of 100 units/mL.
Humalog Mix 75/25: 25% insulin lispro solution mixed with 75% insulin lispro protamine suspension.
Humalog Mix 50/50: 50% insulin lispro solution combined with 50% insulin lispro protamine suspension.

Pharmacological Class

Belongs to the antidiabetic medication class; specifically an insulin formulation.

Pharmacology (Mechanism of Action)

Insulin facilitates glucose utilization in metabolic processes.
Promotes transport of monosaccharides across cell membranes.
Aids in converting amino acids into proteins.
Synthetic insulin with a terminal half-life of approximately 1 hour.

Drug Interactions

No listed interactions classified as Risk D or X.
Hypoglycemic drugs may enhance insulin's hypoglycemic effects.
Hyperglycemic drugs may reduce insulin effectiveness.

Side Effects/Adverse Effects

Possibility of hypoglycemia.
Hypersensitivity reactions can occur, noted by redness, swelling, and itching at the injection site.
Potential for lipodystrophy at the injection site.
The frequency of side effects is unspecified.

Contraindications

Dosage adjustments may be necessary with even minimal changes.
Risk of hypoglycemic reactions during fasting, diarrhea, vomiting, or medication overuse.

Patient Counseling Recommendations

Adhere strictly to prescribed dietary guidelines.
Administer insulin 15 minutes prior to meals.
Avoid changing syringe brands or dosages without consulting a physician.
Seek medical advice during illnesses.
Follow the prescribed order for mixing insulins.
Regular monitoring of blood or urine glucose is advised.
Carry diabetic identification for emergencies.
Store insulin in the refrigerator, avoiding the freezer.
Be aware of hypoglycemia signs: sweating, tremors, blurred vision, weakness, hunger, and confusion; treat with oral glucose or consult a doctor if symptoms appear.

Description

This quiz covers essential information about Insulin Lispro, including its indications for type 1 and type 2 diabetes. Key points include dosing guidelines, medication strengths available, and the pharmacological class of this insulin formulation. Test your knowledge on this important antidiabetic medication!