Questions and Answers
What is the therapeutic class of Insulin Lispro?
What is the pharmaceutical class of Insulin Lispro?
Pancreatics
What are the indications for using Insulin Lispro?
Control of hyperglycemia in patients with type 1 and type 2 diabetes mellitus.
How does Insulin Lispro lower blood glucose?
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The onset of Insulin Lispro is ______, peak is ______, and duration is ______.
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Insulin Lispro is contraindicated in patients with hypoglycemia.
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Insulin Lispro should be used alone in patients with type 1 diabetes.
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Study Notes
Therapeutic Class
- Insulin lispro belongs to the antidiabetics therapeutic class, used for managing diabetes.
- Functions as a hormone, helping regulate blood sugar levels.
Pharmaceutical Class
- Classified under pancreatic agents, integral for glucose metabolism.
Indications
- Prescribed for controlling hyperglycemia in patients diagnosed with type 1 and type 2 diabetes mellitus.
Action
- Lowers blood glucose by stimulating glucose uptake in skeletal muscle and adipose tissue while inhibiting hepatic glucose production.
- Additional insulin actions include:
- Inhibition of lipolysis and proteolysis.
- Enhancement of protein synthesis.
- As a rapid-acting insulin, has quicker onset and shorter duration compared to human regular insulin.
- Often used in conjunction with intermediate- or long-acting insulin for better glycemic control.
Onset/Peak/Duration
- Onset of action: approximately 15 minutes.
- Peak effect occurs around 1 hour after administration.
- Total duration of action is about 3 hours.
Contraindications/Precautions
- Contraindicated for individuals with hypoglycemia or known allergy/hypersensitivity to insulin lispro.
- Use caution in patients experiencing stress or infection, as these conditions may increase insulin requirements temporarily.
- Renal or hepatic impairment can lead to decreased insulin requirements.
- Essential to pair with longer-acting insulin for type 1 diabetes management.
- Should be used cautiously with pioglitazone or rosiglitazone due to increased risk of fluid retention and potential heart failure exacerbation.
- During pregnancy, insulin requirements may rise temporarily.
- Use in pediatric populations requires careful consideration.
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Test your knowledge on Insulin Lispro with these flashcards. Explore key concepts including therapeutic and pharmaceutical classes, indications, and the action of this important antidiabetic medication. Perfect for students and healthcare professionals.
